The metabolic needs of cells are determined by function and fate. Pluripotent cells must make the choice to either self-renew, or commit to alternative cell fates. What are the changes in metabolic programs and cell bioenergetics associated with this stem cell choice? Do cell fate decisions determine metabolic activity, or do metabolic switches trigger the commitment to alternative cell fates? How do rapidly proliferating cells signal their comprehensive needs for more ATP, reducing equivalents, and biosynthetic intermediates that provide for growth and division? Can small molecules be used to divert stem cells toward expansion of desired lineages for cell-based therapies? Speakers at this symposium will present their latest metabolomic findings on stem cell metabolism vs. lineage commitment — and how this knowledge may be applied for future therapies.
*Reception to follow.
This event will also be broadcast as a webinar; registration is required.
*Please note: Transmission of presentations via the webinar is subject to individual consent by the speakers. The Introduction (Dr. Gross) and first Keynote Presentation (Dr. Peter Carmeliet) will not be included in the webinar transmission for this symposium, and the anticipated webinar start time is 10:30 AM Eastern Time. To access all speakers' presentations in full, we invite you to attend the live event in New York City.
|Nonmember (Student / Postdoc / Resident / Fellow)