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  • Academy Events

  • MicroRNAs: A Gene Silencing Mechanism with Therapeutic Implications

    Wednesday, July 13, 2016 | 9:00 AM - 5:00 PM
    The New York Academy of Sciences

    Presented by the Biochemical Pharmacology Discussion Group

    Related Content

    MicroRNAs (miRNAs) are single-stranded RNAs about 22 nucleotides in length that repress the expression of specific proteins by annealing to complementary sequences in the 3′ untranslated regions (UTRs) of target mRNAs. Apart from their posttranscriptional expression, or silencing, miRNAs may also direct mRNA destabilization and cleavage. Moreover, rather than targeting a single disease-associated protein target as many small molecule drugs and antibodies do, each miRNA may serve to repress the expression of numerous proteins involved in the pathogenesis and progression of various diseases and could therefore potentially interfere with multiple disease-promoting signal transduction pathways. Because aberrant expression of miRNAs has been implicated in numerous disease states, miRNA-based therapies have sparked much interest for the treatment of a variety of diseases. The objective of this symposium is to bring together investigators who have led the field in describing what miRNAs do and their potential in treating diseases, as well as those who are translating these findings into promising drug candidates, some of which have already advanced into early stage clinical trials.

    * Reception to follow.

    Registration Pricing

    Member $60
    Member (Student / Postdoc / Resident / Fellow) $25
    Nonmember (Academia) $105
    Nonmember (Corporate) $160
    Nonmember (Non-profit) $105
    Nonmember (Student / Postdoc / Resident / Fellow) $70

    Webinar Pricing

    This event will also be broadcast as a webinar; registration is required.

    Please note: Transmission of presentations via the webinar is subject to individual consent by the speakers. Therefore, we cannot guarantee that every speaker's presentation will be broadcast in full via the webinar. To access all speakers' presentations in full, we invite you to attend the live event in New York City where possible.

    Member $0
    Member (Student / Postdoc / Resident / Fellow) $0
    Nonmember (Academia) $20
    Nonmember (Corporate) $35
    Nonmember (Non-profit) $20
    Nonmember (Student / Postdoc / Resident / Fellow) $10


    The Biochemical Pharmacology Discussion Group is proudly supported by:

    • Boehringer Ingelheim
    • Regeneron

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