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Translational Medicine Initiative
The Translational Medicine Initiative represents a three-year partnership between The New York Academy of Sciences and the Josiah Macy, Jr. Foundation.
This Initiative has enabled the formation of the Translational Medicine Discussion Group. This interdisciplinary Group provides a unique, recurring forum that unites physicians with basic researchers, industry and academic scientists, public health experts, and others to spark an interdisciplinary and scholarly discussion of recent breakthroughs and remaining challenges in translating basic science into clinical applications. Discussions will catalyze innovation regarding how to better integrate the teaching of basic, cutting-edge science in medical education, in addition to examining diseases and pathologies present in urban environments in a unique and interdisciplinary manner.
To learn about the latest advances in the translation of basic research into clinical application, join us at an upcoming meeting or see our unique library of Publications and Multimedia below.
Translational Medicine Initiative: Career Development
An ongoing mission of the Academy's Science Alliance program is to build a consortium of universities, teaching hospitals, and independent research facilities committed to advancing the careers of students and postdocs across multiple institutions and disciplines.
The Josiah Macy, Jr. Foundation also provided funds to sponsor a limited number of free, one-year student memberships to the New York Academy of Sciences. All of the slots under this membership offer have now been filled and we can no longer accept new members. If you are interested in Academy membership, please visit the Member Center to learn more about membership and to join. Presented by
The Josiah Macy, Jr. Foundation is a privately endowed philanthropy dedicated to supporting programs designed to broaden and improve the education of and collaboration among medical and health care professionals.
Silver Sponsor
Upcoming Initiative Events
Friday, February 24, 2012 | 8:15 AM - 7:30 PM
Organizers: Erica Friedman, David Muller and Karen Zier (Mount Sinai School of Medicine)
Opening Remarks: George Thibault (The Josiah Macy Jr. Foundation)
This conference will discuss benefits, such as improved analytic, creative, and critical-thinking skills and practical issues of implementing mandatory research training for all medical students.
Past Initiative Events
December 1 - 3, 2011
Organizers: Gregory J. del Zoppo (University of Washington School of Medicine), Andrei V. Alexandrov (University of Alabama at Birmingham)
Presented as part of the Translational Medicine Initiative, this 2.5-day conference will explore the state-of-the-art and future directions of research and clinical practice leading to enhanced medical care in the acute treatment of ischemic stroke.
Tuesday, March 29, 2011 | 1:00 PM - 5:00 PM
Organizers: Lorrence H. Green (Westbury Diagnostics) and Jennifer Henry (The New York Academy of Sciences)
Routine blood screening protocols test for several common pathogens, but miss others such as XMRV. This symposium will discuss recent advances in the testing and screening of the blood supply as well as suggestions for future directions. Presented as part of the Translational Medicine Initiative.
March 9 - 11, 2011
Organizers: Stephen Marder (University of California, Los Angeles School of Medicine), Bita Moghaddam (University of Pittsburgh) and Bryan Roth (University of North Carolina School of Medicine)
This conference will facilitate the translation of discoveries in basic neuroscience into the development of innovative pharmacological agents for the treatment of schizophrenia by convening and encouraging dialogue among clinical, translational and basic neuroscientists. Presented as part of the Translational Medicine Initiative.
Thursday, February 10, 2011 | 1:00 PM - 5:00 PM
Speakers: Michael B. Sporn (Dartmouth Medical School), Elizabeth A. Grimm (MD Anderson Cancer Center), Dmitry Gabrilovich (H. Lee Moffitt Cancer Center), Colin Meyer (Reata Pharmaceuticals, Inc.) and Stephen T. Sonis (Harvard/Farber Cancer Center)
Reactive oxygen and nitrogen species (RONS) are implicated in cancer and inflammation pathogenesis. This symposium covers the mechanisms that regulate their generation and metabolism, their role in disease, and the development of novel therapeutics. Presented as part of the Translational Medicine Initiative.
Tuesday, January 25, 2011 | 1:00 PM - 5:00 PM
Speakers: Per Gjorstrup (Resolvyx Pharmaceuticals), Karsten Gronert (University of California, Berkeley), Mauro Perretti (Queen Mary University of London), Charles N. Serhan (Harvard University, Brigham & Women's Hospital), Ira Tabas (Columbia University), and Edward Thorp (Columbia University)
Chronic inflammation contributes to the progression of many common diseases. This symposium reviews advances in treating chronic inflammatory diseases by promoting active resolution of inflammation instead of only blocking proinflammatory mediators. Presented as part of the Translational Medicine Initiative.
Tuesday, November 16, 2010 | 1:00 PM - 5:00 PM
Speakers: Greg Hannon (Cold Spring Harbor Laboratory), Pier Paolo Pandolfi (Harvard Medical School), John Rinn (Harvard Medical School), Ramin Shiekhattar (The Wistar Institute), David Spector (Cold Spring Harbor Laboratory)
Non- coding RNAs are emerging as important regulators of development and function in many physiological processes. Their role in controlling pathogenesis and their potential as targets for therapeutic intervention are becoming increasingly apparent. Presented as part of the Translational Medicine Initiative.
Tuesday, September 28, 2010 | 1:00 PM - 5:00 PM
Speakers: Fadi G. Akar (Mount Sinai School of Medicine), Roger J. Hajjar (Mount Sinai School of Medicine), Walter J. Koch (Thomas Jefferson University), and Evangelia Kranias (University of Cincinnati College of Medicine)
Development of therapies to treat heart failure is hampered by a lack of understanding of underlying mechanisms. This symposium reviews current and potential therapeutic approaches, and research to identify useful molecular targets. Presented as part of the Translational Medicine Initiative.
Wednesday, June 23, 2010 | 8:15 AM - 5:30 PM
Despite vast advances in biomedical research and technology, the medical school curriculum has remained mostly static for the past half century. This goal of this conference is to highlight innovative new models for physician training motivated by advances in science and technology, and to consider how to more closely link basic science and clinical training. Presented as part of the Translational Medicine Initiative.
Monday, May 24, 2010 | 1:00 PM - 5:30 PM
Organizers: Doris Bucher (New York Medical College), Jennifer Henry (The New York Academy of Sciences)
Influenza viruses such as H1N1 continue to pose a major global public health problem, so understanding their pathogenicity and transmission is crucial. This symposium will revisit the 2009 outbreak and examine strategies against future outbreaks. Presented as part of the Translational Medicine Initiative.
Initiative Publications
Multimedia eBriefings
Access expert online multimedia reports of Academy events with Academy eBriefings.
February 3, 2011
Organizers: Senthil K. Muthuswamy (Cold Spring Harbor Laboratory and Ontario Cancer Institute), Pier Paolo Pandolfi (Harvard Medical School), and Jennifer Henry (The New York Academy of Sciences).
Small RNAs do not code for proteins, but they nonetheless have an important role to play in the regulation of the development and execution of many cellular processes crucial to overall physiological well-being. Scientists are increasingly aware of these molecules' part in controlling disease pathogenesis and of their potential as targets for therapeutic intervention. At a November 16, 2010 symposium called Non-coding RNAs in Oncogenesis researchers gathered at The New York Academy of Sciences to explore the role of non-coding RNAs in oncogenesis, focusing on how they affect methylation patterns or interact with messenger RNAs to regulate gene expression, the role they play in cellular differentiation, and how they bind proteins to modulate protein function.
November 1, 2010
Organizers: Charles A. Lunn (Merck Research Laboratories), Martin A. Schwarz (Mount Sinai School of Medicine), and Jennifer Henry (New York Academy of Sciences)
Development of therapies to treat heart failure is hampered by a lack of understanding of underlying mechanisms. This symposium reviews current and potential therapeutic approaches, and research to identify useful molecular targets.
September 14, 2010
Despite vast advances in biomedical research and technology, the medical school curriculum has remained mostly static for the past half century. The goal of this conference was to highlight innovative new models for physician training motivated by advances in science and technology, and to consider how to more closely link basic science and clinical training.
July 23, 2010
Organizers: Doris Bucher (New York Medical College) and Jennifer Henry (The New York Academy of Sciences)
Influenza viruses such as H1N1 continue to pose a major global public health problem, so understanding their pathogenicity and transmission is crucial. This symposium revisited the 2009 outbreak and examined strategies against future outbreaks.
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Volume 1205 S1, September 2010
Volume 1205 S1, September 2010
This collection of meeting reports includes scholarly summaries of two discussion groups that took place at the New York Academy of Sciences, "HIV/AIDS: Vaccines and Alternative Strategies for Treatment and Prevention" and "H1N1 Swine Flu: The 2010 Perspective"
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Podcasts
September 2, 2011
Heart disease is the leading death for Americans today. In this special edition of the Science & the City podcast, hear what Dr. Valentin Fuster, director of the Wiener Cardiovascular Institute at the Mount Sinai School of Medicine, and scientific organizer of the Academy's upcoming conference on cardiovascular health in Barcelona, Spain, has to say about heart healthy behavior in children, youth, and adults.
April 14, 2011
Good oral hygiene helps prevent tooth decay and gum disease, but the health of your mouth may have a big impact on the rest of your body too—especially if you have diabetes.
September 24, 2010
Three experts who spoke at a recent Academy conference discuss what personalized medicine is, the technology behind it, and how it will change the patient's experience.
Other Related Events in Translational Research and Medicine
Friday, February 24, 2012 | 8:15 AM - 7:30 PM
Organizers: Erica Friedman, David Muller and Karen Zier (Mount Sinai School of Medicine)
Opening Remarks: George Thibault (The Josiah Macy Jr. Foundation)
This conference will discuss benefits, such as improved analytic, creative, and critical-thinking skills and practical issues of implementing mandatory research training for all medical students.
Tuesday, February 28, 2012 | 1:00 PM - 5:00 PM
Organizers: Andrew Alt (Bristol-Myers Squibb), Jennifer Henry (The New York Academy of Sciences)
Speakers: P. Jeffrey Conn (Vanderbilt University), Christian Felder (Eli Lilly and Company), Adam Hendricson (Bristol-Myers Squibb), Celine Valant (Monash University, Victoria, Australia)
Allosteric modulation of GPCRs as a therapeutic strategy offers improved selectivity and safety. This symposium discusses emerging screening strategies for allosteric modulators and in vitro assessment of allosteric modulator activity.
Tuesday, March 27, 2012 | 1:00 PM - 5:00 PM
Organizers: Seongeun (Julia) Cho (US Food and Drug Administration), Jennifer Henry (The New York Academy of Sciences)
Speakers: Darrell R. Abernethy (US Food and Drug Administration), Angela Birnbaum (University of Minnesota), Jenny Y. Chien (Eli Lilly), Jeremy D. Walston (Johns Hopkins University School of Medicine), Molly E. Zimmerman (Albert Einstein College of Medicine)
Older individuals are the major users of many medications, yet clinical data to support evidence-based therapy are often lacking. This symposium presents clinical, regulatory and industry considerations in investigating drugs for older patients.
Wednesday, April 4, 2012 | 5:30 PM - 7:30 PM
Organizers: S. Marvin Friedman (Hunter College, CUNY), Jennifer S. Henry (The New York Academy of Sciences)
Speakers: Bonnie Bassler (Howard Hughes Medical Institute and Princeton University), Arturo Casadevall (Albert Einstein College of Medicine)
Research into obscure organisms can aid drug development from unexpected angles. Speakers discuss the use of quorum sensing to develop anti-microbial agents, and a potential therapy for human melanoma discovered in the study of fungal melanin.
Monday, April 16, 2012 | 9:00 AM - 5:00 PM
Organizers: Steven Gross (Weill Cornell Medical College), Irwin Kurland (Albert Einstein College of Medicine), Jennifer Henry (The New York Academy of Sciences)
Speaker: Christopher B. Newgard (Duke University Medical Center)
The explosive rise in obesity and diabetes (diabesity) threatens the health of many in Western and developing Asian countries. This symposium focuses on the discovery potential of metabolomics and other 'omics to elucidate the causes and effects.
Tuesday, April 17, 2012 | 8:30 AM - 5:00 PM
Organizers: Johanna P. Daily (Albert Einstein College of Medicine), David A. Fidock (Columbia University Medical Center), Takushi Kaneko (TB Alliance), and Jennifer Henry (The New York Academy of Sciences)
Speakers: Johanna P. Daily (Albert Einstein College of Medicine), Kirk W. Deitsch (Weill Cornell Medical College), David A. Fidock (Columbia University Medical Center), Manuel Llinás (Princeton University), Victor Nussenzweig (NYU Langone Medical Center), Chris Plowe (University of Maryland), Ana Rodriguez (NYU Langone Medical Center), Vern L. Schramm (Albert Einstein College of Medicine), Tim Wells (MMV), and Elizabeth Winzeler (Scripps Research Institute)
Malaria control options show promise, with effective vaccines in clinical trials, and candidate drugs to address resistance under development. This symposium examines parasite pathogenesis and intervention, and the development of novel therapies.
Tuesday, April 24, 2012 | 9:00 AM - 5:00 PM
Organizers: Mercedes Beyna (Pfizer), Cheng Chang (Pfizer), Anis Khan (Merck), Tristan Maurer (Pfizer), Jennifer Henry (The New York Academy of Sciences)
Speakers: Cheng Chang (Pfizer), James M. Gallo (Mount Sinai School of Medicine), Donald E. Mager (State University of New York at Buffalo), Tristan Maurer (Pfizer), Matthew Onsum (Merrimack Pharmaceuticals), Eric Stefanich (Genentech, Inc.), Dane Wittrup (MIT), Jing Yu (Novartis)
Modeling and simulation are critical in systematically integrating diverse preclinical information to predict clinical response. In this symposium, guiding principles and specific applications in quantitative translational research will be reviewed.
May 21 - 23, 2012
Organizers: Emma Ciafaloni (University of Rochester), Matthew N. Meriggioli (University of Illinois College of Medicine), Robert L. Ruff (Louis Stokes Cleveland Department of Veterans Affairs Medical Center and Case Western Reserve University), and Gil I. Wolfe (University at Buffalo School of Medicine and Biomedical Sciences)
Review the most recent advances in basic, translational, and clinical research on the rare, acquired disorder, Myasthenia Gravis, with implications for a range of additional autoimmune and neuromuscular diseases.
Other Publications in Translational Research and Medicine
Webcasts
November 17, 2010
Speakers: Barbara M. Alving (NIH), ShaAvhree Buckman (FDA Center for Drug Evaluation and Research), Garret A. FitzGerald (University of Pennsylvania), Ruth E. March (AstraZeneca), Laura K. Richman (R&D Translational Science) and Orla Smith (Science Translational Medicine)
This November, MedImmune and the New York Academy of Sciences are co-hosting a press forum to explore the critical role of Translational Science to future therapeutic breakthroughs and to the personalization of medicine (with a focus in oncology, but also including other disciplines such as inflammatory or cardiovascular disease).
View Archived Webcast
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Multimedia eBriefings
Access expert online multimedia reports of Academy events with Academy eBriefings.
November 1, 2010
Organizers: Charles A. Lunn (Merck Research Laboratories), Martin A. Schwarz (Mount Sinai School of Medicine), and Jennifer Henry (New York Academy of Sciences)
Development of therapies to treat heart failure is hampered by a lack of understanding of underlying mechanisms. This symposium reviews current and potential therapeutic approaches, and research to identify useful molecular targets.
September 14, 2010
Despite vast advances in biomedical research and technology, the medical school curriculum has remained mostly static for the past half century. The goal of this conference was to highlight innovative new models for physician training motivated by advances in science and technology, and to consider how to more closely link basic science and clinical training.
July 23, 2010
Organizers: Doris Bucher (New York Medical College) and Jennifer Henry (The New York Academy of Sciences)
Influenza viruses such as H1N1 continue to pose a major global public health problem, so understanding their pathogenicity and transmission is crucial. This symposium revisited the 2009 outbreak and examined strategies against future outbreaks.
April 5, 2010
Organizer: Vincent P. Tomaselli (Center for Advanced Information Management, Columbia University)
The switch to electronic health records promises to save money, improve patient care, and facilitate information sharing. But implementation is expensive and privacy concerns remain. A recent Academy conference addressed all these issues.
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Volume 1189, issue S1, March 2010
This Annals online meeting report presents an summary of the "Fourth Annual Translational Stem Cell Research Conference: Breaking Ground", sponsored by the New York Stem Cell Foundation.
Edited by Raymond P. Donnelly (Center for Drug Evaluation & Research (CDER), Food and Drug Administration, Rockville, Maryland) Volume 1182, December 2009
This volume includes presentations by experts from academia, industry and government on the scientific and clinical basis for the successes and failures of recombinant cytokines and cytokine antagonists as therapeutic agents.
Edited by Ralph Steinman (The Rockefeller University, New York, New York), Jacques Banchereau (Baylor Institute for Immunology Research, Dallas, Texas), and Olivera J. Finn (School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania) Volume 1174, September 2009
From world-renowned researchers and clinicians, manuscripts in this volume shed light on recent steps forward in immunotherapeutic and preventive approaches for future cancer vaccines.
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