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  • Academy eBriefings

  • eBriefing

    Career Building in Nontraditional Postdoc Tracks

    Speakers: Susan D. Croll (Regeneron), Uzi de Haan (Cornell Tech), and Karen Hanson Widbin (Pfizer)

    This eBriefing looks at nontraditional postdoctoral tracks in drug discovery and applied research.

    In this eBriefing

    • Understanding the differences between academic and industry postdoc positions
    • Planning for nontraditional career tracks in business and technology
    • Navigating opportunities and challenges in industry
  • Recent eBriefings 

    March 24, 2015

    Career Building in Nontraditional Postdoc Tracks

    Speakers: Susan D. Croll (Regeneron), Uzi de Haan (Cornell Tech), and Karen Hanson Widbin (Pfizer)

    This eBriefing looks at nontraditional postdoctoral tracks in drug discovery and applied research, considering the structure of postdoc programs in industry and opportunities for innovation and creativity.

    March 5, 2015

    Diabetic Kidney Disease: Drug Discovery and Clinical Development Challenges

    Organizers: Magdalena Alonso-Galicia (MAG Pharma Consulting LLC), Ken Jones (Allergan), Scott MacDonnell (Boehringer Ingelheim Pharmaceuticals), and Jennifer Henry (formerly at The New York Academy of Sciences)

    With a poor understanding of its pathogenesis and few biomarkers, identifying and prosecuting drug targets for diabetic kidney disease is challenging. This eBriefing reviews targets for preventive or therapeutic interventions and discusses clinical development.

    March 3, 2015

    Innovative Funding Models for Alzheimer's Disease and Dementia

    Organizers: Cynthia Duggan (The New York Academy of Sciences), Maike Stenull (Johnson & Johnson), and George Vradenburg (Global CEO Initiative on Alzheimer's Disease)
    Keynote Speaker: Dennis Gillings (World Dementia Council)

    This eBriefing explores new public and private funding mechanisms to meet the challenges of financing AD research and care. It considers several investment models and policy initiatives and looks at how best to apply government funds.

    February 6, 2015

    Food Safety Considerations for Nutrition Science

    Keynote Speakers: Robert E. Brackett (Illinois Institute of Technology) and Frank Yiannas (Wal-Mart Stores Inc.)

    This eBriefing considers issues of food security, economics, policy, and communication related to food safety.

    January 30, 2015

    Shaping the Developing Brain: Spotlight on Nutrition and Brain Development

    Speakers: Maureen M. Black (University of Maryland School of Medicine), Edward A. Frongillo (University of South Carolina), Michael K. Georgieff (University of Minnesota), and Betsy Lozoff (University of Michigan)

    This eBriefing highlights research on nutrition and brain development presented at the Fifth Annual Aspen Brain Forum.

    January 30, 2015

    Shaping the Developing Brain: Fifth Annual Aspen Brain Forum

    Keynote Speaker: Thomas R. Insel (National Institute of Mental Health, NIH)

    In early life, massive changes take place in the connectivity and plasticity of the brain that determine the future success of a child. This eBriefing explores cognitive neuroscience research on early development; social, family, and nutritional factors that cause lasting changes in the brain; and intervention, education, and policy initiatives to help at-risk children.

    December 19, 2014

    New Frontiers in the Neurobiology of Mental Illness

    Keynote Speaker: The Honorable Patrick J. Kennedy (Former U.S. Representative, Rhode Island; One Mind for Research; Kennedy Forum)

    This eBriefing explores the translation of neuroscience breakthroughs into therapies for mental illness. A keynote lecture looks at strategies to dispel stigma surrounding mental illness so that new treatments are accessible to all.

    December 16, 2014

    Early-life Influences on Obesity: Pre-conception to Adolescence

    Organizers: John G. Kral (SUNY Downstate Medical Center), Michael Gibney (University College Dublin), Blandine Laferrère (Columbia University), Andrew G. Swick (Metagenics), Karen Teff (National Institutes of Health), Mandana Arabi (The Sackler Institute for Nutrition Science), and Amy Beaudreault (The Sackler Institute for Nutrition Science)

    This eBriefing examines obesity risks that occur in early life and considers how to intervene to prevent and treat diabesity and related diseases. Topics include maternal nutrition, genetics, the microbiome, metabolic disorders, fetal development, generational effects, and early diet.

    December 9, 2014

    Grantsmanship for Graduate Students and Postdocs

    Speaker: Jaime S. Rubin (Columbia University)

    This eBriefing reviews grant writing at the graduate and postdoctoral levels, focusing on how to apply for research grants in the sciences, where to find resources, and how to avoid common mistakes.

    November 21, 2014

    Click Chemistry in Biology and Medicine

    Organizers: Peng Wu (Albert Einstein College of Medicine) and Jennifer Henry (formerly at The New York Academy of Sciences)
    Keynote Speakers: Jim Paulson (Scripps Research Institute) and K. Barry Sharpless (Scripps Research Institute)

    Click chemistry mimics the simplicity of reactions found in nature for synthesizing large complex molecules, proceeding via the stepwise addition of small building blocks with minimal toxic byproducts. This eBriefing explores recent developments in the search for click reactions with applications in disease diagnosis and therapy.

    November 12, 2014

    Elucidating GPCR Functional Selectivity for Drug Development

    Organizers: John A. Allen (Pfizer), Mercedes Beyna (Pfizer), Bryan L. Roth (University of North Carolina School of Medicine), and Jennifer Henry (formerly at The New York Academy of Sciences)

    This eBriefing looks at how to exploit biased ligand signaling at GPCRs to improve therapeutics for cardiovascular and CNS disorders. GPCRs signal via canonical pathways involving G proteins and via other signaling proteins, including β-arrestins. Discovering ligands with the desired signaling bias enables beneficial efficacy while reducing side effects.

    November 5, 2014

    From Bacterial Immunity to Genome Editing: The 2014 Dr. Paul Janssen Award Symposium

    Featured Speakers: Emmanuelle Charpentier (Helmholtz Centre for Infection Research, Hannover Medical School, Germany; Umeå University, Sweden) and Jennifer Doudna (University of California, Berkeley; Howard Hughes Medical Institute)

    This eBriefing features Emmanuelle Charpentier and Jennifer Doudna, recipients of the 2014 Dr. Paul Janssen Award for Biomedical Research for their role in understanding and adapting the CRISPR/Cas system for genome editing. Applications of the technique in human disease research and therapy are also described.

    October 14, 2014

    Fifty Years of the Genetic Code: Honoring the Legacy of Marshall Nirenberg

    Organizers: C. Thomas Caskey (Baylor College of Medicine), Brian Clark (University of Aarhus, Denmark), Gregory A. Petsko (Weill Cornell Medical College), and Jennifer Henry (formerly at The New York Academy of Sciences)

    The identification of the genetic code has offered many opportunities for further scientific discovery. This eBriefing documents a symposium that honored the legacy of Nobel laureate Marshall Nirenberg and showcased research in a range of therapeutic areas.

    September 5, 2014

    Demyelination and Remyelination: From Mechanism to Therapy

    Keynote Speaker: Robin Franklin (Wellcome Trust – MRC Cambridge Stem Cell Institute, University of Cambridge)

    This eBriefing highlights biological and clinical findings in remyelination and repair in genetic, inflammatory, infectious, cerebrovascular, and neurodegenerative conditions and injuries. It also features new techniques for imaging myelin changes in the brain and for screening molecular targets, as well as emerging therapeutics that promote remyelination.

    August 12, 2014

    Advances in Immunomodulation: The 2014 Ross Prize in Molecular Medicine

    Speakers: James P. Allison (University of Texas MD Anderson Cancer Center), Charles A. Dinarello (University of Colorado–Denver), and John J. O'Shea (National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH)

    This eBriefing features John J. O'Shea, recipient of the 2014 Ross Prize in Molecular Medicine for his discoveries in immunology and cytokine biology. Recent research on therapies targeting cytokine signaling in autoimmune and inflammatory diseases and checkpoint modulators in cancer is also described.

    July 17, 2014

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation), Kevin J. Lee (Lawrence Ellison Foundation), and Jennifer Henry (The New York Academy of Sciences)

    Age is the major risk factor for Alzheimer's disease, and key pathways in aging biology offer targets for novel drugs. This eBriefing explores advances in the science of aging and in drug discovery for Alzheimer's and other neurodegenerative diseases.

    July 15, 2014

    HIV 2014: Science, Community, and Policy for Key Vulnerable Populations

    Organizers: Chris Beyrer (Johns Hopkins Bloomberg School of Public Health), Peter Godfrey-Faussett (UNAIDS), Ani Shakarishvili (UNAIDS), Yegor Voronin (Global HIV Vaccine Enterprise), and Jennifer Henry (The New York Academy of Sciences)

    The UNAIDS vision of zero new HIV infections, zero AIDS-related deaths, and zero discrimination calls for a global approach to HIV research and policy. This eBriefing focuses on improving outcomes for HIV in key vulnerable populations.

    July 3, 2014

    Malaria 2014: Advances in Pathophysiology, Biology, and Drug Development

    Organizers: Johanna P. Daily (Albert Einstein College of Medicine), David A. Fidock (Columbia University Medical Center), and Jennifer Henry (The New York Academy of Sciences)
    Keynote Speakers: Jane M. Carlton (New York University), Rick M. Fairhurst (National Institute of Allergy and Infectious Diseases, NIH), and Terrie E. Taylor (Michigan State University)

    Despite a 25% reduction in global malaria mortality since 2000, around half the world's population lives in areas where malaria is endemic. This eBriefing highlights a symposium held on World Malaria Day to examine breakthroughs in pathophysiology, drug development, and pre-erythrocytic and liver-stage biology.

    June 20, 2014

    Affective Disorders: Qatar Clinical Neuroscience Conference

    Chairs: Matthew E. Fink (Weill Cornell Medical College), Javaid I. Sheikh (Weill Cornell Medical College in Qatar), Melanie Brickman Stynes (The New York Academy of Sciences), and Brooke Grindlinger (The New York Academy of Sciences)

    This eBriefing highlights research on affective disorders, debilitating mood-related psychiatric illnesses such as depression and bipolar disorder that result from an intrinsic or chronic dysfunction of the brain, either within the cells or in their connectivity. Topics include animal models, translational medicine, advances in neuropsychiatry, and clinical approaches based on new understanding of disease heterogeneity.

    June 20, 2014

    Stroke and Traumatic Brain Injury: Qatar Clinical Neuroscience Conference

    Chairs: Matthew E. Fink (Weill Cornell Medical College), Javaid I. Sheikh (Weill Cornell Medical College in Qatar), Melanie Brickman Stynes (The New York Academy of Sciences), and Brooke Grindlinger (The New York Academy of Sciences)

    This eBriefing highlights research on brain disorders caused by external conditions such as cerebrovascular disease, stroke, and TBI, which result in the damage or death of healthy, functioning cells and brain tissue. Topics include pathophysiology, therapeutic insights, and clinical care to treat dysfunction and damage.