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eBriefing
Keynote speakers: Alan Cohen (Children's Hospital of Philadelphia),
Chaim Hershko (Shaare Zedek Medical Center), and Sir David Weatherall (University of Oxford)
As this eBriefing reports, new treatments and a potential cure using gene therapy are bringing new hope and health to individuals who suffer from this heritable blood disorder.
In this eBriefing
- New advances toward the goal of reactivating a patient's fetal hemoglobin
- Information about new chelation protocols for removing iron from the liver and heart
- Why supplementing chelation with antioxidants could be more effective at reducing iron overload
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Recent eBriefings
December 22, 2009
Keynote speakers: Alan Cohen (Children's Hospital of Philadelphia),
Chaim Hershko (Shaare Zedek Medical Center), and Sir David Weatherall (University of Oxford)
New treatments and a potential cure using gene therapy are bringing new hope and health to individuals who suffer from this heritable blood disorder.
December 15, 2009
Moderator: Garrick Utley (Levin Institute)
Looking at sectors as diverse as biotechnology, the media, and entrepreneurship, this ongoing series is exploring how New York City could be more competitive in the global economy.
November 11, 2009
A four-part series looking at the state of the art in green building technology and design.
As sensors become more ubiquitous and information technology becomes less expensive, increasingly sophisticated computational tools are being developed to monitor and optimize energy performance.
November 4, 2009
Organizer: Mary Ann Banerji, MD (SUNY Downstate Medical Center)
Minority populations in the United States bear a disproportionate burden of diabetes and related conditions. Causes include genetics, social factors, and a need for more culturally sensitive approaches from the healthcare industry.
October 16, 2009
Speakers: John Koh (University of Delaware), Akira Kawamura (Hunter College, City University of New York), and Tom Kodadek (The Scripps Research Institute)
From traditional Asian herbs to high-tech computational approaches, chemical biologists are using everything in their arsenal to identify promising new drug candidates.
October 13, 2009
Speakers: Frank Slack (Yale University), Ramanjulu Sunkar (Oklahoma State University), Evgeny Nudler (New York University), Anthony Leung (Massachusetts Institute of Technology), Irina Groisman (André Lwoff Institute), Germano Cecere (Columbia University)
Researchers are identifying microRNAs and siRNAs that play roles in the molecular programs regulating the stress response and senescence.
October 2, 2009
Keynote Speaker: Adrian Whitty (Boston University)
Graduate students and postdocs from chemical biology labs around the New York area describe efforts to find and synthesize molecules that bind to proteins or DNA in useful ways.
September 28, 2009
Speakers: Andrea Califano (Columbia University), Galit Lahav (Harvard Medical School), Chris Sander (Memorial Sloan-Kettering Cancer Center), and Arnold Levine (Simons Center for Systems Biology)
Computational and experimental tools for modeling cancer biology are helping to identify common patterns underlying pathogenicity at the cellular and genome levels.
September 21, 2009
Speakers: Senthil Muthuswamy (Cold Spring Harbor Laboratory), Enrique Rodriguez-Boulan (Weill Cornell Medical College), John Condeelis (Albert Einstein College of Medicine), and Ian Macara (University of Virginia School of Medicine)
A change in cell polarity is one of the hallmarks of carcinogenesis, and understanding—and stopping—that transition is now one of the hottest topics in cancer research.
September 18, 2009
Organizers: Anthony Atala (Wake Forest University), Stacie Bloom (New York Academy of Sciences), Yilin Cao (Shanghai Jiao Tong University), Anita Chong (The University of Chicago), Stefanie Dimmeler (University of Frankfurt), Michael P. Sheetz (Columbia University), Qiming Zhan (Chinese Academy of Medical Sciences), Alex Zhang (Sanofi Aventis), Chunhua Zhao (Chinese Academy of Medical Sciences)
Repairing damaged or diseased body parts has long been a goal of medical researchers. This international conference focused on the recent explosion of research progress and the challenges that remain.
September 11, 2009
Speakers: Cynthia Rosenzweig (NASA Goddard Institute for Space Studies), Dickson Despommier (Columbia University Mailman School of Public Health), Ted Caplow (BrightFarm Systems)
Climate change impacts, population growth, rapid urbanization, food safety concerns, and the destructive nature of conventional agriculture together argue for pursuing sustainable agriculture in cities.
August 24, 2009
Keynote Speaker: Russell J. Reiter (The University of Texas Health Science Center)
Our bodies use light cues to regulate fundamental cellular processes. Has overexposure to light and shift work in industrialized societies caused cell growth and proliferation to go awry?
August 20, 2009
A four-part series on sustainable building design.
Green architects and engineers are working to balance energy consumption and generation at the level of individual buildings. But how do we define "zero" energy, and how can we reach this goal?
August 12, 2009
Speakers: Susan Taylor (University of California, San Diego), Vincent Stoll (Abbott Laboratories), Harren Jhoti (Astex Therapeutics), and Stephen Burley (SGX Pharmaceuticals)
Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.
August 11, 2009
Organizer: Albert Ko (Weill-Cornell Medical College)
Regions of Southeast Asia, Africa, and Latin America bear the greatest burden from infectious diseases, in part because life-saving vaccines have not been broadly implemented. How can they be delivered to those who need them most?
August 5, 2009
Keynote Speaker: William W. Li (The Angiogenesis Foundation)
Judah Folkman pioneered the concept of treating cancer by attacking the tumor's supply lines—the capillary blood vessels that feed the tumor. A year after his death, researchers met to discuss new findings and persistent challenges.
August 4, 2009
Speakers: Eric Dufresne (Yale University) and Steven P. Bitler (Landec Corporation)
Researchers are developing "intelligent" materials that respond to changes in their environment in ways that solve engineering challenges. Products like "smart" food packaging have even begun entering the market.
July 24, 2009
Keynote Speakers: E.O. Wilson (Harvard University), John Edward Porter (Research!America), and Dean Kamen (DEKA Research)
Fifty years ago, C.P. Snow identified a lack of understanding between scientists and literary scholars. Panelists at an Academy symposium, summarized in a new eBriefing, say the divide today is between scientists and the general public, with troubling consequences.
July 23, 2009
Organizer: Howard Fillit (Alzheimer's Drug Discovery Foundation)
There's no consensus about what cognitive aging is, but mental decline clearly affects most of us as we grow older. This eBriefing explores how cognitive aging relates to other neurodegenerative disorders and how it may be managed.
July 16, 2009
Speakers: Marina V. Rodnina (Max Planck Institute for Biophysical Chemistry), Hani Zaher (Johns Hopkins School of Medicine), and Ruben L. Gonzalez, Jr. (Columbia University)
Imaging techniques and site-directed mutagenesis are revealing the details of translational fidelity and kinetics at the ribosome. Conformational changes in the ribosome appear to play a key role in these processes.
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