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  • Academy eBriefings

  • eBriefing

    Cytokine Therapies

    Novel Approaches for Clinical Indications

    Organizers: Raymond Donnelly and Amy Rosenberg (U.S. Food and Drug Administration), Howard Young (National Cancer Institute)

    Cytokine-based therapeutics promise new treatments for cancer, autoimmune disorders, and infectious diseases. Can researchers find more effective ways to turn these intercellular messengers into life-saving medicines?

    In this eBriefing

     

    Cytokine therapies show potential against hepatitis C.

    A cytokine treatment for cancer has led to complete remission in some patients.

    Bioengineering and nanotechnology approaches improve bioactivity and delivery of cytokine therapies.

  • Recent eBriefings 

    July 2, 2009

    Cytokine Therapies: Novel Approaches for Clinical Indications

    Organizers: Raymond Donnelly and Amy Rosenberg (U.S. Food and Drug Administration), Howard Young (National Cancer Institute)

    Cytokine-based therapeutics promise new treatments for cancer, autoimmune disorders, and infectious diseases. Can researchers find more effective ways to turn these intercellular messengers into life-saving medicines?

    June 30, 2009

    The Market's Hidden Cards: Algorithmic Trading Strategies

    Speakers: Ian Domowitz (Investment Technology Group) and Lee Maclin (Courant Institute of Mathematical Sciences)

    Algorithmic trading has transformed the finance industry, affecting the way shares are sold in "dark pools" and how portfolio managers and traders interact.

    June 17, 2009

    Careers for Scientists in Pharma: Basic Research, Clinical, and Regulatory Roles

    Speaker: Susi Lee (Merck & Co.)

    Researchers often want to make the jump from an academic lab to a pharmaceutical company. A scientist who made the transition explains the different roles of scientists in industry and what type of person thrives there.

    June 11, 2009

    Zero Net Energy Buildings: Reality or Fiction?

    A four-part series featuring engineers and architects in the field of green building design

    Green architects and engineers are working to balance energy consumption and generation at the level of individual buildings. But how do we define "zero" energy, and how can we reach this goal?

    June 8, 2009

    Clean Technology in New York: A Survey of the State's Strengths and Prospects

    Speakers: Paul DeCotis (New York State Deputy Secretary for Energy), Francis Murray, (NYSERDA), and Edward Reinfurt (NYSTAR); René Bastón, Karin Pavese, and Christopher Cooke (New York Academy of Sciences)

    A report produced by the Academy has identified a number of cleantech fields in which the state has particular R&D strengths. Stakeholders gathered to discuss how to translate these assets into economic development.

    June 3, 2009

    Human Swine Flu (H1N1) and Novel Influenza Pandemics

    Keynote Speaker: Edwin Kilbourne (New York Medical College)

    Vaccine experts and public health officials met at the Academy to discuss the latest about the outbreak. Slides, audio, and video are now available, and a complete meeting report is coming soon.

    May 29, 2009

    Innovate New York: Envisioning an Inventive City

    Moderator: Garrick Utley (Levin Institute)

    How will New York adapt and thrive in turbulent times? Two recent events looked at how to leverage the city's international talent and its status as the hub of the U.S. media industry.

    May 18, 2009

    Profiles in Pluripotence: Systems Biology of Stem Cells

    Speakers: Jeanne Loring (The Scripps Research Institute), Raju Chaganti (Memorial Sloan-Kettering Cancer Center), Ihor Lemischka (Mount Sinai School of Medicine)

    Researchers are using high-throughput techniques to determine how gene expression and epigenetic states affect pluripotency. As this new eBriefing reports, this profiling has identified some key features of stem cells.

    May 12, 2009

    Transforming Principles: MicroRNAs in Muscle and Cardiac Development

    Speakers: Thomas Thum (Julius-Maximilians University), Maha Abdellatif (UMDNJ), Nicholas Sokol (Indiana University), and Rusty Montgomery (miRagen Therapeutics)

    Muscle remodeling occurs as a normal developmental process and in response to damage. MicroRNAs play newly discovered roles in both cases.

    May 4, 2009

    Social Science: How to Shine at Scientific Meetings

    Speakers: Michael Zigmond (University of Pittsburgh) and Colin Purrington (Swarthmore College)

    Two experts in science communication shared their insights on mastering professional conferences, from networking to poster design.

    April 29, 2009

    HPV and Cancer: Future Prospects for Vaccination and Screening

    Speakers: Maura Gillison (Ohio State University Medical Center), Philip Castle (National Cancer Institute), Laura A. Koutsky (University of Washington), Eduardo L. Franco (McGill University), and Douglas Lowy (National Cancer Institute)

    A vaccine and new screening approaches can reduce rates of HPV-related cervical and oral cancers. Why is adoption lagging, and how can it be improved?

    April 22, 2009

    In Good Form: Navigating the U.S. Visa and Immigration Process

    Speakers: Suzanne Seltzer and Kate Kalmykov (Klasko, Rulon, Stock & Seltzer, LLP)

    U.S. science thrives on an international workforce, but gaining permission to work in the country can be difficult. Two immigration lawyers explain what foreign national students and postdocs need to know.

    April 14, 2009

    Molecular Diversity: New Compounds for Research and Drug Discovery

    Speakers: John Porco (Boston University), R. Kip Guy (St. Jude Children's Research Hospital), and Daniel A. Erlanson (Carmot Therapeutics, Inc.)

    The search for chemicals that will serve as drugs and research tools is unrelenting. Three scientists discuss innovative approaches to meeting this need.

    April 6, 2009

    Glass Buildings: The Energy Challenge

    Speakers: Nancy E. Anderson (Sallan Foundation), Chris Benedict (Architecture and Energy Limited), Scott Frank (Jaros Baum & Bolles), Adrian Tuluca (Viridian Energy & Environmental LLC), and Michael Bobker (CUNY)

    Glass buildings are appealing for their views and daylight exposure. But even with sophisticated modifications to regulate energy transmission, they may not be sustainable.

    April 2, 2009

    Betting on Biotech: Careers in Equity Research

    Speaker: Eric Staeva-Vieira (Majestic Research)

    Expertise in the sciences, combined with financial smarts, can be a ticket to Wall Street, where equity analysts advise investors on the best bets in their field.

    March 30, 2009

    Translational Cancer Research: Bench, Bedside, and Community

    Keynote speakers: Robert Weinberg (MIT and Whitehead Institute), Olufunmilayo Olopade (University of Chicago Medical Center)

    Speakers at this Hunter College Gene Center symposium looked at mechanisms of cancer progression, and how social and racial differences affect cancer outcomes.

    March 24, 2009

    Biomarkers in Brain Disease: Biological and Regulatory Challenges

    Keynote speaker: William Potter (Merck Research Laboratories)

    Neurological and psychiatric conditions need good biomarkers. And if new candidates are identified, better standards and protocols for validating them will be necessary. NYAS organized a conference in Oxford to help push the field forward.

    March 20, 2009

    Neural Architecture: Systems Approaches to Brain Structure and Function

    Speakers: Dmitri B. Chklovskii (Howard Hughes Medical Institute), Jonathan D. Victor (Weill Cornell Medical College), and Roger D. Traub (IBM T.J. Watson Research Center)


    The brain is a complex system with many layers and myriad interconnections. Computational strategies have helped reveal its underlying organization and how neural signaling works.

    March 9, 2009

    Shine a Light: High-Resolution Microscopy and Imaging in Biology

    Speakers: Jennifer Lippincott-Schwartz (NIH), Maribel Vazquez (City College, CUNY), and Charles Humphrey (U.S. Centers for Disease Control and Prevention)


    The black box of the cell is becoming increasingly transparent as scientists use fluorescent tags, microfluidic systems, and electron microscopy to reveal its structures and functions.

    March 3, 2009

    Power Couple: Plug-in Hybrid Electric Vehicles and a Smart Grid

    Speakers: Mark Duvall (Electric Power Research Institute), Arthur Kressner (Con Edison), Richard Drake (NYSERDA)


    Electric cars are commanding serious attention. But mass-market success requires, among other factors, better and cheaper batteries and a smart grid. New York State is pursuing both aggressively.