Comments*

 
  • Academy eBriefings

  • eBriefing

    Surgery and Cognition

    Delirium, Cognitive Decline, and Opportunities to Protect the Brain

    Featuring: Sharon Inouye (Harvard Medical School)

    Surgery helps millions of Americans overcome illness to live longer, healthier lives. Yet surgery can lead to delirium, cognitive decline, and perhaps even a higher long-term risk of dementia for many patients, a risk that is poorly understood and often under-recognized in the clinic. With numerous factors—including age—contributing to each patient's level of risk, what are the challenges and opportunities to create biomarkers and therapeutics for those who are most vulnerable?

    In this eBriefing

    • Establishing links between postoperative delirium and later dementia.
    • Mapping the role of anesthesia in cognitive function and brain activity after surgery in the elderly.
    • Identifying changes in Alzheimer's disease biomarkers after anesthesia and surgery.
  • Recent eBriefings 

    November 21, 2016

    Surgery and Cognition: Delirium, Cognitive Decline, and Opportunities to Protect the Brain

    Featuring: Sharon Inouye (Harvard Medical School)

    Surgery helps millions of Americans overcome illness to live longer, healthier lives. Yet surgery can lead to delirium, cognitive decline, and perhaps even a higher long-term risk of dementia for many patients, a risk that is poorly understood and often under-recognized in the clinic. With numerous factors—including age—contributing to each patient's level of risk, what are the challenges and opportunities to create biomarkers and therapeutics for those who are most vulnerable?

    October 18, 2016

    HIV 2016: HIV and Non-Communicable Diseases

    Featured Speaker: Peter Godfrey-Faussett (UNAIDS)

    Participants gathered at the New York Academy of Sciences to discuss one of the next frontiers in the HIV field: how NCDs and HIV interact, how they should be treated, and how policy needs to adapt to facilitate effective treatment for people living with NCDs.

    September 22, 2016

    The Physics of Everything

    Is there a limit to human knowledge? Where do philosophy and physics intersect? Are we alone in the universe? Answering these and other questions, this six-part series united some of our most vibrant public intellectuals and communicators for explorations that reflect on the current state of modern physical sciences, its greatest mysteries and future endeavors, and its philosophical significance for our understanding of reality and the spiritual dimension of human existence.

    August 10, 2016

    Food–Microbiome Interaction: Implications for Health and Disease

    Keynote Speakers: John Bienenstock (McMaster University, Canada) and Jeffrey Gordon (Washington University in St. Louis)

    This eBriefing discusses the links between gut microbiota, diet, and health. It covers topics including the microbiome in development; microbiome interactions outside the gut; and the therapeutic potential of targeting the microbiome.

    July 8, 2016

    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Centre, University of Cambridge, UK) and Craig B. Thompson (Memorial Sloan Kettering Cancer Center)

    This eBriefing covers the latest research on pediatric cancers, including topics such as etiological differences between pediatric and adult cancers, epigenetics, mechanisms of metastasis and disease recurrence, risk factors, diagnostics, and novel treatment approaches.

    July 7, 2016

    Epigenetics: Cancer and Beyond

    Organizers: Donald McCaffery (Resverlogix Corp.), Norman Wong (Resverlogix Corp.), Sarah Zapotichny (Resverlogix Corp.), George Zavoico (Jones Trading Institutional Services), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)
    Keynote Speaker: Craig B. Thompson (Memorial Sloan Kettering Cancer Center)

    Epigenetic abnormalities contribute to tumorigenesis and various diseases beyond cancer. This eBriefing describes recent progress in validating the therapeutic potential of small molecule inhibitors targeting epigenetic marks.

    July 6, 2016

    Disease Drivers of Aging: The 2016 Advances in Geroscience Summit

    Keynote Speakers: Richard Hodes (National Institute on Aging, NIH), Felipe Sierra (National Institute on Aging, NIH), Steven Austad (University of Alabama at Birmingham), and Elissa Epel (University of California, San Francisco)

    This eBriefing looks at how chronic diseases—specifically HIV/AIDS, diabetes, and cancer—affect aging, with a focus on the seven mechanistic pillars of aging.

    June 2, 2016

    Neuronal Connectivity in Brain Function and Disease

    Organizers: Thomas F. Franke (NYU School of Medicine), Eric Nestler (Icahn School of Medicine at Mount Sinai), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)

    Detailed understanding of neuronal connectivity promises unprecedented insights into the brain and its disorders and new options for diagnosis and therapy. This eBriefing explores work to map the brain and define its circuitry.

    May 26, 2016

    Advances in Human Microbiome Science: Gut–Brain Interaction

    Organizers: John Hambor (Boehringer Ingelheim), Sarkis Mazmanian (California Institute of Technology), Nilufer Seth (Pfizer), Erick Young (Boehringer Ingelheim), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)

    There is growing interest in the connection between gut microbiota and the central nervous system. This eBriefing discusses gut–brain interactions and the possibility of targeting the microbiome with a focus on CNS health.

    May 17, 2016

    Emerging Approaches to Cancer Immunotherapy

    Organizers: Renier Brentjens (Memorial Sloan Kettering Cancer Center), George Zavoico (Jones Trading Institutional Services), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)

    Cancer immunotherapy, which engages the immune system to detect and destroy cancer cells, has gained popularity and success in recent years. This eBriefing features investigational approaches to better engineer or train the immune system to improve its responses, combat treatment resistance, and avoid adverse effects.

    May 13, 2016

    Editor's Guide to Writing and Publishing Your Paper

    Speaker: Brooke Grindlinger, Chief Scientific Officer, Scientific Programs & Blavatnik Awards (The New York Academy of Sciences)

    Publishing is critical to the scientific profession yet few opportunities exist for science PhDs to gain formal training in this area. A former editor for the Journal of Clinical Investigation provided an inside look into the editorial review process and how to present scientific results.

    April 26, 2016

    Regenerative Medicine: Transitioning Therapeutics from Cells to the Clinic

    Organizers: Jane S. Lebkowski (Asterias Biotherapeutics), George Zavoico (JonesTrading Institutional Services), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)

    The field of regenerative medicine is burgeoning with cell-based therapies designed to enhance or correct cell function. This eBriefing considers efforts to rethink clinical, regulatory, and manufacturing approaches to accelerate the transition of these therapies to the clinic.

    April 19, 2016

    Developing Scientists through Outreach

    Keynote Speakers: Emily Rice (College of Staten Island, CUNY), Mark Stewart (SUNY Downstate Medical Center), and Robert Tai (University of Virginia)

    Placing STEM students and postdocs in K–12 learning environments to mentor and teach is a well-known strategy to repair the leaky STEM pipeline. This eBriefing reviews STEM mentoring programs and other outreach strategies for scientists.

    March 16, 2016

    Microbes in the City: Mapping the Urban Genome

    Keynote Speakers: Jo Handelsman (White House Office of Science and Technology Policy), W. Ian Lipkin (Columbia University), Curtis Huttenhower (Harvard T.H. Chan School of Public Health), and Coby Schal (North Carolina State University)

    Metagenomics uses high-throughput DNA sequencing to study the huge populations of unculturable microbes in the urban environment. This eBriefing reviews work to map the urban metagenome to probe the microbial communities in the buildings and subways, soil and sewers in our cities.

    March 3, 2016

    Clinical and Nutrition Interventions to Manage Disease-related Loss of Lean Body Mass

    Organizers: David Evans (Ohio State University), Refaat Hegazi (Abbott Nutrition Health Institute), Gerard Mullin (Johns Hopkins Medicine), Dennis H. Sullivan (University of Arkansas for the Medical Sciences), Kathy West (Abbott Nutrition Health Institute), Amy R. Beaudreault (The Sackler Institute for Nutrition Science), and Julie Shlisky (The Sackler Institute for Nutrition Science)

    Hospitalized patients frequently experience loss of muscle mass and function, with negative outcomes for recovery, quality of life, and mortality. This eBriefing reviews interventions, including investigational strategies, for disease-related muscle mass loss.

    February 12, 2016

    Little Beans, Big Opportunities: Using Pulses to Meet Today's Global Health Challenges

    Keynote Speaker: Sonny Ramaswamy (USDA National Institute of Food and Agriculture)

    The United Nations declared 2016 the International Year of Pulses, highlighting the potential of dry peas, beans, lentils, and chickpeas to improve human health and agricultural sustainability. This eBriefing considers how pulse consumption contributes to health and how food systems could be improved to promote pulse production.

    February 2, 2016

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Organizers: Robert Martone (St. Jude Children's Research Hospital) and Sonya Dougal (The New York Academy of Sciences)

    Tau pathology is a hallmark of many devastating neurological disorders, including frontotemporal dementia, TBI, Down syndrome, focal cortical dysplasia, and Alzheimer's disease. This eBriefing explores tau-related mechanisms of neurodegeneration and emerging therapeutic strategies focused on tau.

    January 28, 2016

    Toward Evidence-based Nutrition Policy: Methods, Implementation, and Political Reality

    Keynote Speakers: Sonia Angell (NYC Department of Health and Mental Hygiene) and Rogan Kersh (Wake Forest University)

    Public policy for nutrition aims to assist people in making healthier food choices. This eBriefing looks at current evidence in nutrition policy making, including assessments of recent public policy interventions intended to improve nutrition and reduce obesity.

    January 25, 2016

    Pre-Approval Access: Can Compassion, Business, and Medicine Coexist?

    Organizers: Alison Bateman-House (NYU School of Medicine), Melanie Brickman Stynes (The New York Academy of Sciences), Arthur Caplan (NYU School of Medicine), Brooke Grindlinger (The New York Academy of Sciences), and Erick Tatro (The New York Academy of Sciences)

    This eBriefing explores pre-approval access to investigational medicines, the prospective benefits of which may outweigh the potential risks for critically ill patients. In a series of debates, representatives of governments, pharmaceutical companies, patient groups, NGOs, and foundations discussed ethical and safety challenges for pre-approval access and compassionate use programs.

    January 22, 2016

    Current Evidence on Noncaloric Sweeteners and their Health Implications

    Speakers: Gary D. Foster (Weight Watchers International Inc.), John Glendinning (Barnard College), and Rick Mattes (Purdue University)

    This eBriefing examines the current research on noncaloric sweeteners approved by the Food and Drug Administration for use in foods and beverages in the United States, particularly studies assessing how the compounds affect weight management and health.