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  • Life Sciences & Biomedical Research

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    Annals

    Special Issue: The Potential of Pulses to Meet Today's Health Challenges

    Edited by Annals of the New York Academy of Sciences editorial staff.

    The United Nations declared 2016 as the International Year of Pulses (IYP) to highlight the importance of increasing pulse production and consumption

    eBriefing

    Microbial Influences in Cardio–Metabolic Diseases

    Featuring: Henrik Bjørn Nielsen (Clinical-Microbiomics A/S), Martin J. Blaser (New York University Langone Medical Center), Patrice D. Cani (Universite Catholique de Louvain, LDRI), Rachel Carmody (Harvard University), Stanley L. Hazen (Cleveland Clinic), Gerald I. Shulman (Yale University School of Medicine), Marion Soto (Joslin Diabetes Center, Harvard Medical School), and Dan Winer (University of Toronto)

    The microbiome is emerging as an important regulator of health and disease well beyond the digestive tract. This eBriefing surveys highlights from recent research innovations and therapeutic applications from the microbiome with a focus on metabolic disease.

    Annals

    Special Issue: The Year in Diabetes and Obesity

    Edited by Rexford Ahima (Johns Hopkins University School of Medicine)

    Scholarly reviews of current topics in diabetes and obesity

    eBriefing

    Understanding Autophagy to Enhance Clinical Discovery: The 2016 Dr. Paul Janssen Award Symposium

    Featuring: Yoshinori Ohsumi (Tokyo Institute of Technology)

    In 2016, Yoshinori Ohsumi won the Nobel Prize for his ground-breaking research on autophagy, which demonstrated the crucial process it serves in maintaining cellular homeostasis, as well as established its role in human health. This eBriefing covers Ohsumi's presentation, in which he reflected on his initial work on the key players in autophagy and shared his vision for future advancements in the field. Following his award lecture, fellow prominent scientists at the forefront of autophagy research discussed emerging concepts and technologies, which are included as well.

    Annals

    Special Issue: Staple Crops Biofortified with Vitamins and Minerals - Considerations for a Public Health Strategy

    Edited by Juan Pablo Peña-Rosas (World Health Organization), Maria Nieves Garcia-Casal (Venezuelan Institute for Scientific Research)

    Papers from a World Health Organization and Academy workshop on biofortification

    Volume 1390

    Free online access provided by the World Health Organization

    eBriefing

    Equivalence of Complex Drug Products: Scientific and Regulatory Challenges

    Organizers: Melanie Brickman Borchard (The New York Academy of Sciences), Alison Carley (The New York Academy of Sciences), Daan J.A. Crommelin (Utrecht University), Wenlei Jiang (US Food and Drug Administration), Scott McNeil (Nanotechnology Characterization Laboratory), Vinod Shah (Non Biological Complex Drugs Working Group), and Jon de Vlieger (Lygature)

    This eBriefing looks at approaches for complex drug development and regulation, outstanding challenges in the assessment of complex drug equivalence, consequences for product interchangeability, and comparisons of biological and non-biological complex drug families.

    Annals

    Special Issue: The Year in Evolutionary Biology

    Edited by Charles W. Fox (University of Kentucky) and Timothy A. Mousseau (University of South Carolina)

    Eleven scholarly review articles discuss topics in evolutionary biology and genetics

    eBriefing

    Advances in the Neurobiology of Mental Illness

    Speakers: Tyrone D. Cannon (Yale University), K. Ranga Rama Krishnan (Rush Medical College), Husseini Manji (Janssen Research & Development, LLC), Vaibhav Narayan (Janssen Research & Development, LLC), Daniel Pine (National Institute of Mental Health, US National Institutes of Mental Health), and B. Timothy Walsh (New York State Psychiatric Institute, Columbia University)

    At this symposium, scientists, physicians, clinicians, other allied healthcare providers, policy makers, and patients explored new scientific understanding of the neurobiology of a range of mental illnesses.

    Annals

    Special Issue: Antimicrobial Therapeutics Reviews

    Edited by Gerald D. Wright (McMaster University)

    Nine scholarly review articles discussing aspects of antibiotic resistance

    eBriefing

    Aging and Nutrition: Novel Approaches and Techniques

    Speakers: Jan van Deursen (The Mayo Clinic), Vadim Gladyshev (Harvard University), Matt Kaeberlein (University of Washington), Vera Gorbunova (University of Rochester), Nicholas Stroustrup (Harvard University), and Arlan Richardson (University of Oklahoma)

    This eBriefing documents how prominent researchers in the field came together to explore the interplay between aging, nutrition, and metabolism, as well as the important role that novel technologies will play in current and future studies.