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  • Biochemistry, Biophysics & Structural Biology

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    eBriefing

    Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

    Organizer: Steven Gross (Weill Cornell Medical College)
    Keynote Speaker: Lewis C. Cantley (Weill Cornell Medical College)
    Speakers: Shuibing Chen (Weill Cornell Medical College), Ubaldo Martinez-Outschoorn (Thomas Jefferson University), and Andre Terzic (Center for Regenerative Medicine, Mayo Clinic)

    Does stem cell fate dictate metabolic activity or do metabolic switches trigger a commitment to cell fate? This eBriefing presents the latest research on stem cell metabolism, lineage commitment, and future therapies.

    Annals

    Annals Meeting Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents the following three meeting reports (1) Biomarkers in nutrition: new frontiers in research and application; (2) The new revolution in toxicology: The good, the bad, and the ugly; and (3) Neuroprotection after cerebral ischemia.

    Volume 1278

    Free online access provide by the Sackler Institute for Nutrition Science

    eBriefing

    The 8th Gotham-Metro Condensed Matter Meeting: Tapping NYC's Science and Engineering Talent

    Keynote Speakers: KC Huang (Stanford University) and Amir Yacoby (Harvard University)
    Panel Moderator: Seth Pinsky (NYC Economic Development Corporation)

    This eBriefing documents the 8th condensed matter physics conference featuring keynote talks in hard matter and soft matter as well as a special panel discussion, "Generation Tech: Tapping NYC's Science & Engineering Talent," featuring representatives of the new engineering and applied science institutions that are being created in the city.

    eBriefing

    The Paradox of Overnutrition in Aging and Cognition

    Organizers: Deborah R. Gustafson (SUNY Downstate Medical Center; University of Gothenburg, Sweden), John G. Kral (SUNY Downstate Medical Center), and Mandana Arabi (The Sackler Institute for Nutrition Science)

    Alzheimer's disease is expected to triple in the U.S. by 2050 and obesity is already epidemic. This eBriefing presents research on the link between overnutrition and cognition which suggests that obesity may play a role in and age-related diseases.

    eBriefing

    Targeting Metals in Alzheimer's and Other Neurodegenerative Diseases

    Organizers: Rudolph Tanzi (Massachusetts General Hospital and Harvard Medical School), George Zavoico (MLV), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Robert A. Cherny (The Florey Institute of Neuroscience and Mental Health, Australia), Steven M. Hersch (Massachusetts General Hospital and Harvard Medical School), Rudolph Tanzi (Massachusetts General Hospital and Harvard Medical School), and Daniel Tardiff (Whitehead Institute for Biomedical Research)

    Transition metals including Fe, Zn, and Cu affect neurotransmission and are implicated in Parkinson's, Huntington's, and Alzheimer's diseases. This eBriefing reviews mechanisms for restoring the physiological balance of these metals in the brain.

    eBriefing

    The MicroRNA Revolution: The 2012 Dr. Paul Janssen Award Symposium

    Speakers: Eric Lai (Memorial Sloan-Kettering Cancer Center), Allison Abbott (Marquette University), Victor Ambros (University of Massachusetts Medical School), Gregory J. Hannon (Cold Spring Harbor Laboratories, Howard Hughes Medical Institute), Oliver Hobert (Columbia University Medical Center), and Gary Ruvkun (Massachusetts General Hospital and Harvard Medical School)

    This eBriefing features Victor Ambros and Gary Ruvkun, recipients of the 2012 Dr. Paul Janssen Award for Biomedical Research for their role in the discovery of microRNA. Recent research on microRNA is also described.

    eBriefing

    Cracking the Neural Code: Third Annual Aspen Brain Forum

    Keynote Speakers: George Church (Harvard Medical School), Sean Hill (École Polytechnique Fédérale de Lausanne), Allan Jones (Allen Institute for Brain Science), Christof Koch (Allen Institute for Brain Science), and David Van Essen (Washington University in St. Louis)

    One of the greatest challenges in neuroscience today is deciphering how the activity of neurons and circuits gives rise to higher order cognition and behavior. Researchers working at the forefront of systems and computational neuroscience discussed work to crack the neural code, describing advances in tools, technologies, imaging, informatics, and computational models for mapping neural networks.

    eBriefing

    Phosphatidylserine Asymmetry: Therapeutic Applications in Cancer and Infectious Disease

    Speakers: Alan Schroit (UT Southwestern Medical Center), David Ucker (University of Illinois at Chicago), Ari Helenius (ETH Hönggerberg, Switzerland), Chris Reutelingsperger (Maastricht University, The Netherlands), and Philip E. Thorpe (UT Southwestern Medical Center)

    This eBriefing highlights recent developments in the understanding of PS exposure, its biological consequences, and its exploitation to create novel agents for the detection and treatment of cancer and viral diseases.

    eBriefing

    From Colloidal Systems to Frustrated Magnets: 7th Gotham-Metro Condensed Matter Meeting 2012

    Keynote Speakers: Leon Balents (University of California, Santa Barbara) and Mohammad F. Islam (Carnegie Mellon University)

    At the seventh biannual Gotham-Metro Condensed Matter conference faculty, postdocs, and students shared ideas and research on condensed matter with fellow physicists, covering the spectrum from graphene-based transistors and novel chemical sensors to the fundamentals of colloids, metamaterials, and quantum spin liquids.

    eBriefing

    New Thoughts about Causes, Prevention, and Treatment of Childhood Obesity

    Keynote Speaker: David B. Allison (University of Alabama at Birmingham)

    Perhaps the most disturbing facet of the rise in obesity worldwide is the rise in childhood obesity. This eBriefing features researchers, physicians, teachers, and other professionals at the front lines of the childhood obesity epidemic who met in Bimghamton, NY to discuss this alarming public health problem.