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    Annals

    Special Issue: Data Science, Learning, and Applications to Biomedical and Health Sciences

    Edited by Nabil R. Adams (Rutgers University)

    Big Data can provide insights and drive discovery that will accelerate biomedical advances, improve patient outcomes, and reduce costs.

    Annals

    Special Issue: Human Health in the Face of Climate Change

    Edited by Xavier Rodó (Catalan Institute for Climate Sciences)

    This Annals issue discusses the latest research on the effects of climate and environmental changes on human health, including on the transmission of infectious diseases and the epidemiology of noncommunicable diseases.

    Volume 1382

    eBriefing

    Mobile Health: The Power of Wearables, Sensors, and Apps to Transform Clinical Trials

    Organizers: Glen de Vries (Medidata Solutions), John J. Mastrototaro (Medtronic), Bernard Munos (FasterCures), Fiorenzo Omenetto (Tufts University), Leonard Sacks (U.S. Food and Drug Administration), Melanie Brickman Stynes (The New York Academy of Sciences), Brooke Grindlinger (The New York Academy of Sciences), and Daniel Radiloff (The New York Academy of Sciences)

    This eBriefing considers the use of data from wearable sensors and mobile devices in medical care and clinical trials and looks at security and regulatory issues for health data.

    Annals

    Annals Reports: (1) Evolutionary Dynamics and Information Hierarchies in Biological Systems: Aspen Center for Physics Workshop and (2) Cracking the Neural Code: Third Annual Aspen Brain Forum

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents a collection of papers stemming from two conferences: (1) Evolutionary Dynamics and Information Hierarchies in Biological Systems: Aspen Center for Physics workshop; and (2) Cracking the Neural Code: Third Annual Aspen Brain Forum.

    Volume 1305

    eBriefing

    Health 2.0: Digital Technology in Clinical Care

    Organizers: Johanne Morne (New York State Department of Health AIDS Institute), Sonja Noring (New York State Department of Health AIDS Institute), Cheryl Smith (New York State Department of Health AIDS Institute), AIDS Institute Social Media Workgroup (New York State Department of Health AIDS Institute), Brooke Grindlinger (The New York Academy of Sciences), and Kerstin Hofmeyer (The New York Academy of Sciences)

    This eBriefing looks at the impact of digital technologies on clinical care, especially for HIV and other sexually transmitted infections, exploring eHealth strategies for patient-centered care and clinical decision support.

    eBriefing

    Finding the Needle in the Data Haystack: The Implications of a Data-driven Built Environment

    Speakers: Chris Garvin (Terrapin Bright Green), Cliff Majersik (Institute for Market Transformation), and Chris Pyke (U.S. Green Building Council)

    There is an increasing focus on policy, standards, and interoperability of building data. Without the proper tools, the virtual tsunami of building data can overwhelm potential users. This eBriefing focuses on refining the data stream to drive green building innovation.

    eBriefing

    Single-Cell Level Systems Biology

    Speakers: Grégoire Altan-Bonnet (Memorial Sloan-Kettering Cancer Center), Narendra Maheshri (Massachusetts Institute of Technology), Johan Paulsson (Harvard Medical School), and Chris Wiggins (Columbia University)
    Organizers: Andrea Califano (Columbia University), Manuel Duval (Network Therapeutics Inc.), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)

    Fluorescence microscopy advances have opened new avenues in the study of molecular dynamics in single cells. This eBriefing features systems biologists working on the elucidation of the effects of noise in mathematical and experimental methods analyzing single cells.

    eBriefing

    The Reactivity of the Cellular Transcriptome to Xenobiotic Compound Perturbation

    Speakers: Duane C. Hassane (Weill Cornell Medical College), Rui-Ru Ji (Bristol-Myers Squibb), and Aravind Subramanian (Broad Institute of MIT and Harvard University)
    Organizers: Andrea Califano (Columbia University), Manuel Duval (Network Therapeutics Inc.), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)

    The transcriptome of the cell is dynamic, and varies according to chemical perturbations. This eBriefing explores connectivity maps, dose-dependent transcriptome responses, the characterization of drug activity, and chemical genomics in cancer.

    eBriefing

    Building a Knowledge-based Economy in Qatar: Qatar Foundation Annual Research Forum 2011

    This eBriefing highlights research and policy work discussed at the Qatar Foundation Annual Research Forum. Topics include cultures of entrepreneurship, scientific publishing, innovation in the Arab world, knowledge-based economies, structures of R&D enterprises, regional and global partnerships, and much more.

    eBriefing

    The Systems Biology of Aging and Neurodegenerative Diseases

    Organizers: Andrea Califano (Columbia University), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Domenico Accili (Columbia University), David T. Burke (University of Michigan), and David Galas (Institute for Systems Biology, Seattle)

    In this eBriefing systems and computational biologists examine aging and neurodegenerative diseases, covering genetics and the development and application of new technologies, to increase our understanding of these complex biological networks.