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    eBriefing

    Health 2.0: Digital Technology in Clinical Care

    Organizers: Johanne Morne (New York State Department of Health AIDS Institute), Sonja Noring (New York State Department of Health AIDS Institute), Cheryl Smith (New York State Department of Health AIDS Institute), AIDS Institute Social Media Workgroup (New York State Department of Health AIDS Institute), Brooke Grindlinger (The New York Academy of Sciences), and Kerstin Hofmeyer (The New York Academy of Sciences)

    This eBriefing looks at the impact of digital technologies on clinical care, especially for HIV and other sexually transmitted infections, exploring eHealth strategies for patient-centered care and clinical decision support.

    eBriefing

    Finding the Needle in the Data Haystack: The Implications of a Data-driven Built Environment

    Speakers: Chris Garvin (Terrapin Bright Green), Cliff Majersik (Institute for Market Transformation), and Chris Pyke (U.S. Green Building Council)

    There is an increasing focus on policy, standards, and interoperability of building data. Without the proper tools, the virtual tsunami of building data can overwhelm potential users. This eBriefing focuses on refining the data stream to drive green building innovation.

    eBriefing

    Single-Cell Level Systems Biology

    Speakers: Grégoire Altan-Bonnet (Memorial Sloan-Kettering Cancer Center), Narendra Maheshri (Massachusetts Institute of Technology), Johan Paulsson (Harvard Medical School), and Chris Wiggins (Columbia University)
    Organizers: Andrea Califano (Columbia University), Manuel Duval (Network Therapeutics Inc.), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)

    Fluorescence microscopy advances have opened new avenues in the study of molecular dynamics in single cells. This eBriefing features systems biologists working on the elucidation of the effects of noise in mathematical and experimental methods analyzing single cells.

    eBriefing

    The Reactivity of the Cellular Transcriptome to Xenobiotic Compound Perturbation

    Speakers: Duane C. Hassane (Weill Cornell Medical College), Rui-Ru Ji (Bristol-Myers Squibb), and Aravind Subramanian (Broad Institute of MIT and Harvard University)
    Organizers: Andrea Califano (Columbia University), Manuel Duval (Network Therapeutics Inc.), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)

    The transcriptome of the cell is dynamic, and varies according to chemical perturbations. This eBriefing explores connectivity maps, dose-dependent transcriptome responses, the characterization of drug activity, and chemical genomics in cancer.

    eBriefing

    Building a Knowledge-based Economy in Qatar: Qatar Foundation Annual Research Forum 2011

    This eBriefing highlights research and policy work discussed at the Qatar Foundation Annual Research Forum. Topics include cultures of entrepreneurship, scientific publishing, innovation in the Arab world, knowledge-based economies, structures of R&D enterprises, regional and global partnerships, and much more.

    eBriefing

    The Systems Biology of Aging and Neurodegenerative Diseases

    Organizers: Andrea Califano (Columbia University), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Domenico Accili (Columbia University), David T. Burke (University of Michigan), and David Galas (Institute for Systems Biology, Seattle)

    In this eBriefing systems and computational biologists examine aging and neurodegenerative diseases, covering genetics and the development and application of new technologies, to increase our understanding of these complex biological networks.

    eBriefing

    Toward an in silico Cell

    Organizers: Tom S. Leyh (Albert Einstein College of Medicine) and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Adrian H. Elcock (University of Iowa), Ruben L. Gonzalez, Jr. (Columbia University), Zaida Luthey-Schulten (University of Illinois at Urbana–Champaign), Julio Ortiz (Max Planck Institute of Biochemistry, Germany), and Klaus Schulten (University of Illinois at Urbana–Champaign)

    Accurately modeling molecular behavior of cells remains a Holy Grail of the biomodeling community. In this eBriefing, hear leading experts in computational and experimental analysis of large biosystems discuss this field.

    eBriefing

    RECOMB Regulatory Genomics / Systems Biology / DREAM Conference 2010

    Organizers: Ziv Bar-Joseph (Carnegie Mellon University), Andrea Califano (Columbia University), Manolis Kellis (MIT), and Gustavo Stolovitzky (IBM Research)

    This meeting brought together computational and experimental scientists in regulatory genomics and systems biology to discuss latest findings and establish new collaborations towards a systems-level understanding of regulatory networks and gene expression.

    eBriefing

    The Systems Biology of Bugs

    Speakers: Richard Bonneau (New York University), Saeed Tavazoie (Princeton University), and Yuhai Tu (IBM T.J. Watson Research Center)
    Organizers: Andrea Califano (Columbia University), Aris Economides (Regeneron Pharmaceuticals), Gustavo Stolovitzky (IBM Research), and Jennifer Henry (New York Academy of Sciences)

    Systems biologists and computational biologists discussed their combined methods for examining bacterial genomes and elucidating basic signal transduction mechanisms and the genetic basis of phenotypes in biologically, environmentally and clinically important bacteria.

    eBriefing

    Green Building Solutions: What's Working?

    A four-part series looking at the state of the art in green building technology and design.

    Part 3 of the Green Building eBriefing series looks at post-occupancy evaluation of energy efficient buildings.