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  • Clinical Medicine

  • Events 

    Tuesday, March 24, 2015 | 11:45 AM - 4:00 PM

    Positive Allosteric Modulators for Challenging GPCRs: Identification and Optimization

    Speakers: P. Jeffrey Conn (Vanderbilt University), Ron Dror (Stanford University), Christopher Fotsch (Amgen), Corey Hopkins (Vanderbilt University), Whitney Nolte (Pfizer)

    In this symposium, academic and industry scientists will describe the identification, characterization, and development of PAMs for challenging GPCRs.

    Tuesday, April 7, 2015 | 8:30 AM - 4:30 PM

    Cytokine-Based Immunotherapies

    Keynote Speaker: James W. Mier (Beth Israel Deaconess Medical Center/ Harvard Medical School, Boston, MA)
    Speakers: Stephen D. Gillies (Provenance Biopharmaceuticals, Carlisle, MA), Jerome Ritz (Harvard Medical School), Gilles Uzé (Université Montpellier II, Montpellier, France), K. Dane Wittrup (Massachusetts Institute of Technology, Cambridge, MA)

    Systemic toxicity currently prevents exploiting the potential of many cytokines to treat cancer, viral infections, inflammatory and autoimmune conditions. Targeted delivery of immune-stimulatory or immune-regulatory cytokines offers much promise.

    Thursday, April 16, 2015 | 8:00 AM - 7:00 PM

    Nutrition and the Science of Disease Prevention: A Systems Approach to Support Metabolic Health

    Speakers: Brian Bennett (University of North Carolina), Kevin Hall (National Institute of Health), Frank Hu (Harvard School of Public Health), Rudolph Leibel (Columbia University), Anne McCartney (University of Reading), Christina A. Roberto (Harvard T.H. Chan School of Public Health)

    This one-day conference will highlight the connection between nutrition and the complex science of preventing disease. Speakers will focus on promotion of optimal metabolic health, building on input from several complementary disciplines.

    Monday, April 27, 2015 | 8:30 AM - 4:15 PM

    Non-Motor Symptoms: Unraveling the "Invisible" Face of Parkinson’s Disease

    Speakers: Erwan Bezard (University of Bordeaux), Patrick Brundin (Van Andel Institute), K. Ray Chaudhuri (NPF Parkinson's International Centre of Excellence, Kings College London), Marie-Francoise Chesselet (David Geffen School of Medicine at UCLA), Maurizio Facheris (Michael J. Fox Foundation for Parkinson's Research), Horacio Kaufmann (NYU Langone Medical Center), Olivier Rascol (Toulouse University Hospital), Daniel Weintraub (University of Pennsylvania)

    This symposium will review clinical tools for the diagnosis and treatment of non-motor symptoms of Parkinson's disease, discuss the disease mechanisms, and address preclinical models for the development of new therapeutics.

    May 14 - 15, 2015 | Spain

    Human Health in the Face of Climate Change: Science, Medicine, and Adaptation

    Speakers and Session Chairs: Matthew Baylis (University of Liverpool), Jose A. Centeno (The Joint Pathology Center, US Department of Defense), Peter Diggle (Lancaster University), Kristie L. Ebi (University of Washington), Carlos Pérez García-Pando (International Research Institute for Climate and Society, Columbia University), Lisa Goddard (International Research Institute for Climate and Society, Columbia University), Elisabet Lindgren (Stockholm Resilience Centre), Jane Olwoch (University of Pretoria), Mercedes Pascual (University of Michigan), Richard Paul (Institut Pasteur), Town Peterson (The University of Kansas), Jan Semenza (European Centre for Disease Prevention and Control (ECDC)), Jeffrey Shaman (Columbia University)

    Discover the latest research on climate change and its effects on human health, including vulnerability due to extreme weather events, land-use change and agricultural production, variable epidemiology of parasites and infectious diseases, and climate-altering pollutants.

  • Past Events

    Tuesday, February 24, 2015 | 8:30 AM - 4:30 PM

    Harnessing the Potential of Genome Editing for Drug Discovery: Translational Frontiers of in vitro and in vivo Applications

    Speakers: Chad Cowan (Harvard University), James Inglese (National Center for Advancing Translational Sciences, NIH), J. Keith Joung (Massachusetts General Hospital), Randall Platt (Massachusetts Institute of Technology), Yi Yang (Novartis Institutes for Biomedical Research), Lei (Stanley) Qi (University of California San Francisco)

    The emergence of genome editing technologies such as TALEN and CRISPR/Cas9 are revolutionizing our ability to rapidly engineer mammalian systems. This symposium explores the frontiers of genome editing and potential to aid therapeutic development.

    Tuesday, December 9, 2014 | 8:00 AM - 5:00 PM

    Diabetic Kidney Disease: Drug Discovery and Clinical Development Challenges

    Speakers: Matthew D. Breyer (Eli Lilly and Company), Frank C. Brosius (University of Michigan Medical School), Benjamin D. Humphreys (Brigham and Women's Hospital), Matthias Meier (F. Hoffmann-La Roche Ltd), Shahnaz Shahinfar (S. Shahinfar Consulting, Inc. and The Children's Hospital of Philadelphia), Katalin Susztak (University of Pennsylvania), Aliza Thompson (Food and Drug Administration)

    Identifying and prosecuting drug targets is challenging due to a poor understanding of pathogenesis and few biomarkers. This symposium identifies targets for preventive or therapeutic interventions and discusses challenges in clinical development.

    November 11 - 13, 2014

    Shaping the Developing Brain: Prenatal through Early Childhood
    Fifth Annual Aspen Brain Forum

    Keynote Speaker:Thomas R. Insel (National Institute of Mental Health)
    Speakers: Tracy L. Bale (University of Pennsylvania), Jay Belsky (University of California, Davis), Maureen Black (University of Maryland), Pia Britto (UNICEF), Serena Counsell (King's College London), Martha Farah (University of Pennsylvania), Edward Frongillo (University of South Carolina), Michael Georgieff (University of Minnesota), Takao Hensch (Harvard University), Sharon Lynn Kagan (Columbia University), Patricia Kuhl (Washington University), Ed Lein (Allen Institute for Brain Science), Betsy Lozoff (University of Michigan), Linda Mayes (Yale School of Medicine), Andrew N. Meltzoff (Washington University), Charles A. Nelson (Harvard University and Boston Children's Hospital), Joseph Piven (UNC School of Medicine, CIDD), Dana Suskind (University of Chicago), Nim Tottenham (UCLA)

    Discover the latest cognitive neuroscience research on infant and early childhood development; social, family, and nutritional factors that cause lasting changes to the brain; and intervention, education, and policy to help at-risk children.

    Monday, November 3, 2014 | 8:00 AM - 4:30 PM

    Gene Network Changes in Alzheimer's Disease: Potential Points for Therapeutic Intervention

    Speakers: Kwame O. Affram (Uniformed Services University), Erik H.W.G.M. Boddeke (University Medical Center Groningen), Oleg Butovsky (Brigham and Women's Hospital and Harvard Medical School), Philip L. De Jager (Harvard University and Brigham and Women's Hospital), Joseph El Khoury (Massachusetts General Hospital and Harvard Medical School), Miriam Merad (Icahn School of Medicine at Mount Sinai), Michael C. Oldham (University of California, San Francisco), Vishal Sahni (Eisai Inc), Bin Zhang (Icahn School of Medicine at Mount Sinai)

    Next generation sequencing of Alzheimer’s disease (AD) progression reveals gene networks within microglial pathways. This symposium focuses on microglia biology, molecular signatures specific to microglial phenotypes, and phenotype modulation.

  • Publications 

    eBriefing

    Shaping the Developing Brain: Fifth Annual Aspen Brain Forum

    Keynote Speaker: Thomas R. Insel (National Institute of Mental Health, NIH)

    This eBriefing explores cognitive neuroscience research on early development, environmental factors that cause lasting changes in the brain, and initiatives to help at-risk children.

    Annals

    MARROW

    Edited by Mone Zaidi (Mount Sinai School of Medicine, New York, New York)

    A new series in Annals, MARROW presents cutting-edge manuscripts on basic, translational, and clinical bone and bone marrow biology and medicine.

    Annals

    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents two meeting reports: (1) Influencing circadian and sleep–wake regulation for prevention and intervention in mood and anxiety disorders: what makes a good homeostat?; and (2) One Medicine One Science: a framework for exploring challenges at the intersection of animals, humans, and the environment.

    Volume 1334

    Annals

    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents three meeting reports: (1) Head and neck cancer: from research to therapy and cure; (2) Sequencing the head and neck cancer genome: implications for therapy; and (3) New functions and signaling mechanisms for the class of adhesion G protein–coupled receptors.

    Volume 1333

  • Podcasts

    Podcast
    July 30, 2010

    Oxidative Stress

    Foods high in antioxidants are believed to fight oxidative stress. But what is oxidative stress? Two scientists from a recent NYAS conference break it down and discuss whether antioxidants have superpowers.

    Download (12 MB, 00:18:37)
    Podcast
    April 2, 2010

    More than a Yogurt Cup

    Delve into the world of prebiotic and probiotic science. We talk to three people in the field and learn why keeping the good microbes in our bodies happy means a lot for health.

    Download (14 MB, 00:21:21)
    Podcast
    January 29, 2010

    ADHD and the Brain

    Neuropsychologist Jeffrey Halperin is using behavioral therapy on preschoolers with attention deficit hyperactivity disorder (ADHD). He hopes to train their brains to develop in new ways and if effective, his therapies could offer permanent, drug-free treatment for the disorder.

    Download (11 MB, 00:17:30)
    Podcast
    January 15, 2010

    Feeling the Light

    Researchers at Harvard have discovered why the headaches of some migraine sufferers worsen when the person is exposed to light. Rami Burstein, the study's senior author, explains what's happening in the brain, and how they made the breakthrough.

    Download (15 MB, 00:22:48)
  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.