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  • Developmental Biology

  • Events 

    November 6 - 7, 2013

    Alzheimer's Disease Summit: The Path to 2025

    NIA Technical Advisor: Neil Buckholtz (National Institute on Aging)
    Organizers: Alan Cross (AstraZeneca), Sonya Dougal (formerly at The New York Academy of Sciences), Howard Feldman (University of British Columbia), Surya Kolluri (Bank of America), Ian Kremer (Leaders Engaged on Alzheimer's Disease), Tetsuyuki Maruyama (Takeda), Richard C. Mohs (Eli Lilly and Company), Jeffrey S. Nye (Janssen R&D), Ronald C. Petersen (Mayo Clinic), Gregory A. Petsko (Weill Cornell Medical College), Andrea Pfeifer (AC Immune), Thomas Rooney (Sanofi), Darryle D. Schoepp (Merck and Company, Inc.), Diane Stephenson (Critical Path Institute), Rudolph E. Tanzi (Harvard Medical School), John Q. Trojanowski (University of Pennsylvania), Diana L. van de Hoef (The New York Academy of Sciences), George Vradenburg (The Global CEO Initiative on Alzheimer's Disease), Michael Weiner (University of California, San Francisco)

    This conference will convene leading industry, academic, and government stakeholders to discuss how to prevent and effectively treat Alzheimer's by 2025, by coordinating with governmental efforts to build research resources, reengineer our current drug development and evaluation systems, and identify innovative technologies and financing models. The outcome of this meeting will comprise a research agenda that will delineate the pathways needed to effectively treat and prevent Alzheimer's disease by 2025.

  • Past Events

    Monday, June 3, 2013 | 1:00 PM - 4:00 PM

    Genome Integrity Discussion Group Meeting

    Organizers: John Petrini (Memorial Sloan-Kettering Cancer Center), Rodney Rothstein (Columbia University Medical Center), Lorraine Symington (Columbia University Medical Center)
    Keynote Speaker: Stephen West (London Research Institute, Cancer Research UK)
    Speakers: Francisca Lottersberger (de Lange lab, Rockefeller University), Gerard Mazón (Symington lab, Columbia University Medical Center), Jiyong Wang (Jia lab, Columbia University), Christian Zierhut, PhD (Funabiki lab, Rockefeller University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Monday, May 6, 2013 | 8:15 AM - 4:00 PM

    Translating Natural Products into Drugs for Alzheimer's and Neurodegenerative Disease

    Speakers: Kurt R. Brunden (University of Pennsylvania), Grant J. Carr (AMRI), Gabriela Chiosis (Memorial Sloan-Kettering Cancer Center), Jerold Chun (The Scripps Research Institute), Bonnie M. Davis (Synaptec), Chad Dickey (University of South Florida), Frank E. Koehn (Pfizer Global R&D), David J. Newman (National Cancer Institute, NIH), Salvatore Oddo (University of Texas Health Science Center, San Antonio), Giulio Maria Pasinetti (Mount Sinai School of Medicine)

    Alzheimer's disease may benefit from the novel chemistries found in natural products. This conference explores drug discovery from natural products, including novel approaches and technologies, and promising Alzheimer's drug discovery programs.

    Monday, April 1, 2013 | 1:00 PM - 4:00 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Craig Bassing (University of Pennsylvania), Dirk Remus (Memorial Sloan-Kettering Cancer Center), Yossi Shiloh (Tel Aviv University), Mikel Zaratiegui (Rutgers, the State University of New Jersey)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Wednesday, March 20, 2013 | 12:00 PM - 4:00 PM

    Autism Spectrum Disorder: From Genes to Circuits to Behavior

    Speakers: Ben Philpot (University of North Carolina, Chapel Hill), Tim Roberts (The Children's Hospital of Philadelphia), Stephan Sanders (Yale University School of Medicine), Laurence Tecott (University of California, San Francisco), Paul Wang (Seaside Therapeutics)

    Explore recent breakthroughs in early detection of autism and promising therapeutic interventions. This symposium features presents updates on the genetic landscape, the use of mouse models to explore behavior and potential therapeutic biomarkers.

  • Publications 

    eBriefing

    Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

    Organizer: Steven Gross (Weill Cornell Medical College)
    Keynote Speaker: Lewis C. Cantley (Weill Cornell Medical College)
    Speakers: Shuibing Chen (Weill Cornell Medical College), Ubaldo Martinez-Outschoorn (Thomas Jefferson University), and Andre Terzic (Center for Regenerative Medicine, Mayo Clinic)

    Does stem cell fate dictate metabolic activity or do metabolic switches trigger a commitment to cell fate? This eBriefing presents the latest research on stem cell metabolism, lineage commitment, and future therapies.

    eBriefing

    Targeting Metals in Alzheimer's and Other Neurodegenerative Diseases

    Organizers: Rudolph Tanzi (Massachusetts General Hospital and Harvard Medical School), George Zavoico (MLV), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Robert A. Cherny (The Florey Institute of Neuroscience and Mental Health, Australia), Steven M. Hersch (Massachusetts General Hospital and Harvard Medical School), Rudolph Tanzi (Massachusetts General Hospital and Harvard Medical School), and Daniel Tardiff (Whitehead Institute for Biomedical Research)

    Transition metals including Fe, Zn, and Cu affect neurotransmission and are implicated in Parkinson's, Huntington's, and Alzheimer's diseases. This eBriefing reviews mechanisms for restoring the physiological balance of these metals in the brain.

    eBriefing

    The MicroRNA Revolution: The 2012 Dr. Paul Janssen Award Symposium

    Speakers: Eric Lai (Memorial Sloan-Kettering Cancer Center), Allison Abbott (Marquette University), Victor Ambros (University of Massachusetts Medical School), Gregory J. Hannon (Cold Spring Harbor Laboratories, Howard Hughes Medical Institute), Oliver Hobert (Columbia University Medical Center), and Gary Ruvkun (Massachusetts General Hospital and Harvard Medical School)

    This eBriefing features Victor Ambros and Gary Ruvkun, recipients of the 2012 Dr. Paul Janssen Award for Biomedical Research for their role in the discovery of microRNA. Recent research on microRNA is also described.

    eBriefing

    Cracking the Neural Code: Third Annual Aspen Brain Forum

    Keynote Speakers: George Church (Harvard Medical School), Sean Hill (École Polytechnique Fédérale de Lausanne), Allan Jones (Allen Institute for Brain Science), Christof Koch (Allen Institute for Brain Science), and David Van Essen (Washington University in St. Louis)

    One of the greatest challenges in neuroscience today is deciphering how the activity of neurons and circuits gives rise to higher order cognition and behavior. Researchers working at the forefront of systems and computational neuroscience discussed work to crack the neural code, describing advances in tools, technologies, imaging, informatics, and computational models for mapping neural networks.

  • Podcasts

    Podcast
    February 5, 2010

    Advances in Autism

    We talk to two scientists at Hunter College who research different aspects of Autism Spectrum Disorder(ASD). Jason Dictenberg studies synapses in our brain, and Michael Siller looks at play-based therapies for autistic children. Both are on the cutting edge of new research in the field of autism.

    Download (14 MB, 00:21:30)
  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.