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  • Drug Development

  • Events 

    Monday, February 22, 2016 | 9:00 AM - 5:00 PM

    Regenerative Medicine: Transitioning Therapeutics from Cells to the Clinic

    Speakers: John F. DiPersio (Washington University School of Medicine), Jonathan D. Glass (Emory University School of Medicine), Edward O. Lanphier (Sangamo BioSciences, Inc.), Jane S. Lebkowski (Asterias Biotherapeutics), Racheli Ofir (Pluristem LTD), Mahendra Rao (Wake Forest University School of Medicine), Thomas Schulz (ViaCyte, Inc.), John D. Sinden (ReNeuron Limited), Katherine Tsokas (Janssen Research & Development)

    Advances in gene editing have driven an explosion of pre-clinical cell-based therapies. This event addresses the need to rethink clinical, regulatory, & manufacturing approaches to accelerate the transition of drugs through the clinic.

    Monday, February 29, 2016 | 9:00 AM - 5:00 PM

    Emerging Approaches to Cancer Immunotherapy

    Keynote Speakers: Renier Brentjens (Memorial Sloan Kettering Cancer Center), Jedd Wolchok (Memorial Sloan Kettering Cancer Center)
    Speakers: Jane Gross (Emergent Biosolutions, Inc), John Hunter (Compugen Ltd), Jane S. Lebkowski (Asterias Biotherapeutics), Jens-Peter Marschner (Affimed AG), Charles Nicolette (Argos Therapeutics, Inc), Charles L. Sentman (Dartmouth Geisel School of Medicine), David M Spencer (Bellicum Pharmaceuticals), Roland Walter (Fred Hutchinson Cancer Research Center)

    Emerging strategies for Cancer Immunotherapy are changing the face of cancer treatment. This symposium will bring together experts in immunotherapy and immunology to discuss emerging approaches, challenges, and opportunities in this evolving field

    March 30 - April 1, 2016

    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Center, University of Cambridge), Craig B. Thompson (Memorial Sloan Kettering Cancer Center)
    Speakers: Scott Armstrong (Memorial Sloan Kettering Cancer Center), Eric Bouffet (The Hospital for Sick Children, Toronto), Stefan Burdach (Technical University of Munich, Germany), Michael Dyer (St. Jude Children's Research Hospital, Howard Hughes Medical Institute), Nancy Goodman (Kids V Cancer), Lee J. Helman (National Cancer Institute, National Institutes of Health), Nada Jabado (McGill University), Katherine A. Janeway (Dana-Farber Cancer Center, Harvard Medical School), Michael Jensen (Seattle Children's Hospital), Javed Khan (National Cancer Institute, National Institutes of Health), Andrew Kung (Columbia University Medical Center), A. Thomas Look (Dana-Farber Cancer Center, Harvard University), David C. Lyden (Weill Cornell Medical College), Elizabeth Maher (University of Texas Southwestern Medical Center), David Malkin (The Hospital for Sick Children), John Maris (The Children's Hospital of Philadelphia and the University of Pennsylvania), Yael Mossé (The Children’s Hospital of Philadelphia), Kathy Pritchard-Jones (Great Ormond Street Hospital for Children NHS Foundation Trust and University College London), Charles W.M. Roberts (St. Jude Children's Research Hospital), Michel Sadelain (Memorial Sloan Kettering Cancer Center), Paul M. Sondel (University of Wisconsin School of Medicine and Public Health), Poul H. Sorensen (University of British Columbia), Kimberly Stegmaier (Dana-Farber Cancer Institute), Michael D. Taylor (The Hospital for Sick Children, University of Toronto), Matthew Vander Heiden (The Koch Institute, Massachusetts Institute of Technology), Robert Wechsler-Reya (Sanford Burnham Prebys Institute of Medical Discovery)

    Discover the latest on pediatric cancers from leading experts, including etiological differences between pediatric and adult cancers, epigenetics, mechanisms of metastasis and disease recurrence, risk factors, diagnostics, and novel treatment approaches.

    April 13 - 14, 2016

    Disease Drivers of Aging: 2016 Advances in Geroscience Summit

    Speakers: Domenico Accili (Columbia University), Timothy Ahles (Memorial Sloan Kettering Cancer Center), Kathryn Anastos (Albert Einstein College of Medicine), Nir Barzilai (Albert Einstein College of Medicine), James Becker (University of Pittsburgh), Caroline Blaum (New York University), Judith Campisi (Buck Institute for Research on Aging), Harvey J. Cohen (Duke University), Steven Deeks (AIDS Research Institute; University of California, San Francisco), Wendy Demark-Wahnefried (University of Alabama at Birmingham), Elissa Epel (University of California, San Francisco), Kristine Erlandson (University of Colorado), Claudia Gravekamp (Albert Einstein College of Medicine), Jeffrey Halter (University of Michigan), Kevin High (Wake Forest University), Peter Hunt (University of California, San Francisco), Arti Hurria (City of Hope National Medical Center), Beth Jamieson (University of California, Los Angeles), C. Ronald Kahn (Joslin Diabetes Center), Balakuntalam Kasinath (Barshop Institute for Longevity and Aging Studies; University of Texas Health Science Center), Gretchen Neigh (Emory University), Rosario Scalia (Temple University), Jan van Deursen (Mayo Clinic)

    Explore how chronic diseases — specifically HIV/AIDS, diabetes, and cancer — can affect the seven mechanistic pillars of aging.

    Tuesday, April 26, 2016 | 9:00 AM - 5:00 PM

    Solute Carrier Proteins: Unlocking the Gene-Family for Effective Therapies

    Speakers: Dax Fu (John Hopkins School of Medicine), Kathleen M. Giacomini (University of California, San Francisco), Matthias A. Hediger (University of Bern), Avner Schlessinger (Icahn School of Medicine at Mount Sinai), Giulio Superti-Furga (Austrian Academy of Sciences), Ming Zhou (Baylor College of Medicine)

    Solute Carrier Proteins are an untapped resource for drug discovery. This event will discuss breakthroughs in structural biology, cell engineering and metabolomics that hold the promise of "unlocking" this gene family.

  • Past Events

    Tuesday, December 8, 2015 | 8:30 AM - 4:45 PM

    GLP-1 Treatment for Diabetes and Beyond

    Speakers: David D'Alessio (Duke University), Richard DiMarchi (Indiana University), Jean-Philippe Fortin (Pfizer Global), Keld Fosgerau (Zealand Pharma A/S), Matthew R. Hayes (Perelman School of Medicine, University of Pennsylvania), George G. Holz (State University of New York), Beat Jucker (GlaxoSmithKline), Dong Seok Kim (National Institute on Aging / Peptron Inc), Lotte Bjerre Knudsen (Novo Nordisk), Patrick M. Sexton (Monash University), Konrad Talbot (Cedars-Sinai Medical Center)

    GLP-1 receptor agonists have improved treatment options in type 2 diabetes, although realizing their promise in other areas remains challenging. This symposium highlights preclinical and clinical breakthroughs and opportunities for drug development.

    October 28 - 29, 2015

    Pre-Approval Access: Can Compassion, Business, and Medicine Coexist?

    This 2-day colloquium will explore challenges surrounding pre-approval access to investigational medicines in a series of debates featuring prominent representatives of governments, pharmaceutical companies, patient groups, NGOs, and foundations.

    Tuesday, October 27, 2015 | 8:00 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras J. Bauer (Boehringer Ingelheim USA), Myles Fennell (Memorial Sloan-Kettering Cancer Center), Michael R. Jackson (Sanford Burnham Prebys Medical Discovery Institute), Jonathan A. Lee (Eli Lilly), Martin Main (AstraZeneca), Friedrich Metzger (F. Hoffmann-La Roche Ltd), Bruce A. Posner (University of Texas, Southwestern Medical Center), Yao Shen (Columbia University), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Susanne Swalley (Novartis Institutes for Biomedical Research), Jitao David Zhang (F. Hoffmann-La Roche Ltd.)

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

    Thursday, October 15, 2015 | 8:00 AM - 5:00 PM

    Advances in Human Microbiome Science

    Speakers: Jonathan Braun (University of CaliforniaLos Angeles), Rodolphe Clerval (Enterome), Stanislav Dusko Ehrlich (King's College London), Michael A. Fischbach (University of California, San Francisco), Andy Goodman (Yale School of Medicine), Matthew R. Hepworth (Weill Cornell Medical College), Mingzhi Lin (New York University), Randy Longman (Weill Cornell Medical College), Sarkis Mazmanian (California Institute of Technology), Paul O'Toole (University College Cork), Noah W. Palm (Yale University School of Medicine), Tamar Ringel-Kulka (The University of North Carolina at Chapel Hill), R. Balfour Sartor (University of North Carolina School of Medicine)

    In the human colon, the microbiome forms one of the densest bacterial ecosystems known in nature. This symposium will highlight recent research innovations and therapeutic applications from the microbiome with a focus on gut health.

  • Publications 

    eBriefing

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Organizers: Robert Martone (St. Jude Children's Research Hospital) and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing explores tau-related mechanisms of neurodegeneration and emerging therapeutic strategies focused on tau.

    eBriefing

    Pre-Approval Access: Can Compassion, Business, and Medicine Coexist?

    Organizers: Alison Bateman-House (NYU School of Medicine), Melanie Brickman Stynes (The New York Academy of Sciences), Arthur Caplan (NYU School of Medicine), Brooke Grindlinger (The New York Academy of Sciences), and Erick Tatro (The New York Academy of Sciences)

    This eBriefing explores pre-approval access to investigational medicines, the prospective benefits of which may outweigh the potential risks for critically ill patients.

    eBriefing

    Phenotypic and Biomarker-based Drug Discovery

    Organizers: Michael Foley (Tri-Institutional Therapeutics Discovery Institute), Ralph Garippa (Memorial Sloan-Kettering Cancer Center), David Mark (F. Hoffmann-La Roche), Lorenz Mayr (Astra Zeneca), John Moffat (Genentech), Marco Prunotto (F. Hoffmann-La Roche), and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing considers the merits of phenotypic drug discovery, which is experiencing a renaissance of interest. The method aims to find therapeutically useful compounds by screening thousands of substances for functional cellular outputs.

    eBriefing

    Advances in Human Microbiome Science: Intestinal Diseases

    Organizers: Mercedes Beyna (Pfizer), John Hambor (Boehringer Ingelheim), Nilufer Seth (Pfizer), Erick Young (Boehringer Ingelheim), and Sonya Dougal (The New York Academy of Sciences)
    Keynote Speaker: Stanislav Dusko Ehrlich (French National Institute for Agricultural Research; King's College London)

    This eBriefing focuses on the causal relationships between gut microbiota and intestinal health and disease.