• Drug Development

  • Featured Event

    Green Buildings and Health: From the Lab to the Real World

    Wednesday, December 14, 2016 | 6:00 PM - 8:30 PM
    The New York Academy of Sciences

    Researchers at Harvard T.H. Chan School of Public Health and SUNY Upstate Medical University present the results of a new study showing that employees in high-performing, green-certified buildings had higher cognitive function test scores than those in similarly high-performing buildings that were not green certified, even after controlling for other potential explanatory factors.

  • Events 

    Thursday, November 3, 2016 | 9:00 AM - 5:00 PM

    Microbial Influences in Cardio–Metabolic Diseases

    Speakers: Henrik Bjørn Nielsen (Clinical-Microbiomics A/S), Martin J. Blaser (New York University Langone Medical Center), Patrice D. Cani (Universite Catholique de Louvain, LDRI), Rachel Carmody (Harvard University), Stanley L. Hazen (Cleveland Clinic), Gerald I. Shulman (Yale University School of Medicine), Marion Soto (Joslin Diabetes Center, Harvard Medical School), and Dan Winer (University of Toronto)

    The microbiome is emerging as an important regulator of health, and disease well beyond the digestive tract. This symposium will highlight recent research innovations and therapeutic applications from the microbiome with a focus on metabolic disease.

    Wednesday, November 9, 2016 | 8:30 AM - 5:15 PM

    Equivalence of Complex Drug Products: Scientific and Regulatory Challenges

    Keynote Speaker: Lawrence D. Mayer (Jazz Pharmaceuticals)

    Explore approaches for complex drug development and regulation, outstanding challenges in the assessment of complex drug equivalence, consequences for product interchangeability, and compare biological and non-biological complex drug families.

    Thursday, November 10, 2016 | 8:00 AM - 6:00 PM

    Epigenetics in Cancer: Translational Medicine Approaches

    Speakers: Ioannis Aifantis (NYU School of Medicine), Emily Bernstein (Icahn School of Medicine at Mount Sinai), Ryan Kruger (GlaxoSmithKline), Ross L. Levine (Memorial Sloan Kettering Cancer Center), Sheng Li (Jackson Laboratory for Genome Medicine), Christopher E. Mason (Weill Cornell Medicine), Kornelia Polyak (Dana Farber Cancer Institute, Harvard Medical School), Tim Somervaille (The University of Manchester), and Jorge DiMartino (Celgene)

    This conference will explore novel target and validation strategies, translational approaches to assess predictive and response biomarkers, resistance mechanisms, and combination strategies for targeting epigenetic susceptibilities in cancer.

    Tuesday, November 15, 2016 | 9:00 AM - 5:00 PM

    Mucosal Healing of the Intestinal Epithelial Barrier

    Speakers: Thaddeus Stappenbeck (Washington University School of Medicine), Declan F. McCole (University of California Riverside), Jerrold R. Turner (Brigham and Women's Hospital), Linda G. Griffith (MIT), Tim Denning (Georgia State University), and Alan Hanash (Memorial Sloan Kettering Cancer Center)

    This symposium will evaluate emerging research investigating the benefits of achieving mucosal healing in the treatment of intestinal disorders.

    Tuesday, December 6, 2016 | 9:00 AM - 5:00 PM

    Alzheimer's Disease as a Neurovascular Inflammatory Disorder

    Speakers: Katerina Akassoglou (University of California San Francisco), Robert Dempsey (University of Wisconsin), Paula Grammas (University of Rhode Island), Steven Greenberg (Harvard Medical School), Jaime Grutzendler (Yale University), Costantino Iadecola (Weill Cornell Medical College), Jeffrey Iliff (Oregon Health & Science University), Berislav V. Zlokovic (University of Southern California), Heather Snyder (Alzheimer's Association), Zorina Galis (NIH)

    This symposium will highlight basic research and clinical science elucidating the mechanisms underlying the contribution of inflammatory pathways to vascular cognitive impairment and dementia (VCID).

  • Past Events

    Tuesday, October 25, 2016 | 9:00 AM - 5:00 PM

    Emerging Paradigms in Drug Discovery & Chemical Biology

    Speakers: Marcus Bantscheff (Cellzome/GSK), Benjamin F Cravatt (The Scripps Research Institute), Craig Crews (Yale University), Howard Hang (The Rockefeller University), Ruth Nussinov (National Cancer Institute), Brian Raymer (Pfizer), Bryan Roth (University of North Carolina), Eranthie Weerapana (Boston College)

    Chemical Biology is changing the face of drug discovery. This symposium will highlight recent developments in the field, featuring examples from neurobiology and cancer, the ubiquitin proteasome system, GPCRs, and protein lipidation.

    Friday, October 7, 2016 | 9:00 AM - 5:00 PM

    Advances in the Neurobiology of Mental Illness

    Mental illness causes debilitating consequences on quality of life for individuals, families, and society. This symposium explores avenues for translating these discoveries about the neurobiology of a spectrum of mental illnesses into new treatments.

    Thursday, September 8, 2016 | 9:00 AM - 5:00 PM

    Targeting Inflammation and Podocytopathy in Chronic Kidney Disease

    Speakers: Hans-Joachim Anders (University of Munich), John Cijiang He (Icahn School of Medicine at Mount Sinai), Matthias Kretzler (University of Michigan), Kevin V. Lemley (University of Southern California), Jochen Reiser (Rush University Medical Center), Myung K. Shin (Merck & Co. Inc.), Katalin Susztak (University of Pennsylvania), and Roger C. Wiggins (University of Michigan)

    Accumulating evidence supports a role for renal inflammation and podocytopathy in pathogenesis and progression of chronic kidney disease. This symposium will delve into the mechanisms underlying this pathology.

    Wednesday, July 13, 2016 | 9:00 AM - 5:00 PM

    MicroRNAs: A Gene Silencing Mechanism with Therapeutic Implications

    Keynote Speaker: David Bartel (Whitehead/MIT/HHMI)
    Speakers: Paul Grint (Regulus Therapeutics), David S Hong (The University of Texas MD Anderson Cancer Center ), Daniel J Siegwart (University of Texas Southwestern Medical Center), Frank Slack (BIDMC Cancer Center/Harvard Medical School), James W Welsh (The University of Texas MD Anderson Cancer Center)

    miRNAs play critical roles in regulating gene expression. This symposium will present up-to-date basic, translational, and clinical research addressing the biology of miRNA and their promise as a therapeutic target.

  • Publications 


    Special Issue: Countermeasures Against Chemical Threats II

    Edited by Jeffrey D. Laskin (Rutgers University School of Public Health)

    Discussions of various countermeasures to chemical threats.


    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Centre, University of Cambridge, UK) and Craig B. Thompson (Memorial Sloan Kettering Cancer Center)

    This eBriefing covers the latest research on pediatric cancers.


    Epigenetics: Cancer and Beyond

    Organizers: Donald McCaffery (Resverlogix Corp.), Norman Wong (Resverlogix Corp.), Sarah Zapotichny (Resverlogix Corp.), George Zavoico (Jones Trading Institutional Services), Sonya Dougal (The New York Academy of Sciences), and Caitlin McOmish (The New York Academy of Sciences)
    Keynote Speaker: Craig B. Thompson (Memorial Sloan Kettering Cancer Center)

    Epigenetic abnormalities contribute to tumorigenesis and various diseases beyond cancer. This eBriefing describes recent progress in validating the therapeutic potential of small molecule inhibitors targeting epigenetic marks.


    Disease Drivers of Aging: The 2016 Advances in Geroscience Summit

    Keynote Speakers: Richard Hodes (National Institute on Aging, NIH), Felipe Sierra (National Institute on Aging, NIH), Steven Austad (University of Alabama at Birmingham), and Elissa Epel (University of California, San Francisco)

    This eBriefing looks at how chronic diseases—specifically HIV/AIDS, diabetes, and cancer—affect aging, with a focus on the seven mechanistic pillars of aging.