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  • Drug Development

  • Events 

    Friday, April 25, 2014 | 8:00 AM - 5:30 PM

    Malaria 2014: Advances in Pathophysiology, Biology and Drug Development

    Keynote Speakers: Jane M. Carlton (New York University), Rick M. Fairhurst (National Institute of Allergy and Infectious Disease, NIH), Terrie E. Taylor (Michigan State University)
    Speakers: Myles Akabas (Albert Einstein College of Medicine), Purnima Bhanot (UMDNJ - New Jersey Medical School), Liwang Cui (Pennsylvania State University), Mahalia S. Desruisseaux (Albert Einstein College of Medicine), Miriam K. Laufer (University of Maryland School of Medicine), Laura Kirkman (Weill Cornell Medical College), Marcus Lee (Columbia University), Alexander Ploss (Princeton University), Photini Sinnis (Johns Hopkins University)

    Despite a 25% reduction in global malaria mortality since 2000, around half the world's population is at risk. Join us on World Malaria Day to examine breakthroughs in pathophysiology, pre-erythrocytic and liver stage biology, and drug development.

    Friday, May 9, 2014 | 8:00 AM - 4:00 PM

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Speakers: Carmela R. Abraham (Boston University School of Medicine), Eric H. Baehrecke (University of Massachusetts Medical School), Nir Barzilai (Albert Einstein College of Medicine), Jerry R. Colca (Metabolic Solutions Development Company), Brendan D. Manning (Harvard School of Public Health), Beth Stevens (Harvard Medical School), D. Martin Watterson (Northwestern University Feinberg School of Medicine), Haung Yu (Columbia University), Jeffrey W. Kelly (The Scripps Research Institute), Richard I. Morimoto (Northwestern University)

    Age is the major risk factor for Alzheimer's disease, and key pathways in aging biology offer targets for novel drugs. Explore recent advances in the science of aging and innovative drug discovery for Alzheimer's and other neurodegenerative diseases.

    Tuesday, May 20, 2014 | 8:00 AM - 5:00 PM

    Hot Technologies for Developing Next-Gen Biologics

    Speakers: Timothy Charlebois (Pfizer), David King (AnaptysBio Inc.), William M. Pardridge (Brain Research Institute, UCLA), Steven J. Projan (MedImmune), Sachdev Siddhu (University of Toronto), E. Sally Ward (UT Southwestern), Patrick C. Wilson (The University of Chicago), K. Dane Wittrup (Massachusetts Institute of Technology)

    New technologies are pivotal in developing next-generation biologics. This symposium highlights novel technologies in the discovery of new biologics, elucidating in vivo mechanisms of therapeutic proteins, and manufacturing and delivery processes.

    Thursday, June 26, 2014 | 7:45 AM - 5:45 PM

    Demyelination and Remyelination: From Mechanism to Therapy

    Speakers: Douglas Arnold (McGill University), Diego Cadavid (Biogen Idec), Patrizia Casaccia (Mount Sinai School of Medicine), Jonah Chan (University of California, San Francisco), Andrew Eisen (Acorda Therapeutics), Charles ffrench-Constant (MRC Centre for Regenerative Medicine, University of Edinburgh), Vittorio Gallo (Children's National Medical Center and George Washington University), Steven Goldman (University of Rochester Medical Center), Catherine Lubetzki (Pierre and Marie Curie University), Wendy B. Macklin (University of Colorado School of Medicine), David Rowitch (University of California, San Francisco), Bruno Stankoff (Pierre and Marie Curie University)

    This translational conference will highlight biological and clinical findings in myelin development, new techniques for brain imaging and for screening molecular targets, and novel therapeutics that promote remyelination.

    Tuesday, September 30, 2014 | 8:00 AM - 5:00 PM

    Elucidating GPCR Functional Selectivity: Novel Opportunities for Drug Development

    Keynote Speaker: Nobel Laureate Robert J. Lefkowitz (Duke University Medical Center)
    Speakers: Bryan Roth (University of North Carolina at Chapel Hill School of Medicine), Terry Kenakin (University of North Carolina at Chapel Hill School of Medicine), Marc G. Caron (Duke University Medical Center), Laura Bohn (The Scripps Research Institute), Michael Ehlers (Pfizer), JoAnn Trejo (University of California-San Diego), Jonathan Violin (Trevena, Inc.)

    Hear academic, industry, basic and translational researchers, including Nobel Laureate Robert Lefkowitz (Duke University Medical Center) and discuss the development of functionally selective GPCR-biased ligands for CV and CNS disease drug discovery.

  • Past Events

    Thursday, April 10, 2014 | 8:30 AM - 4:30 PM

    Mitochondria, Metabolism and Disease

    Speakers: Robert Balaban (National Heart, Lung, and Blood Institute, NIH), Robert Bao (Massachusetts General Hospital), Salvatore DiMauro (Columbia University Medical Center), Steven Gross (Weill Cornell Medical College), Costas A. Lyssiotis (Weill Cornell Medical College), Jared Rutter (University of Utah School of Medicine), Hazel H. Szeto (Weill Cornell Medical College), Benjamin P. Tu (UT Southwestern Medical Center)

    Damage to mitochondria, which are critical in metabolism, underlies a wide range of human diseases, making them an important therapeutic target. Researchers aim to characterize and cure diseases arising from aberrant mitochondrial metabolism.

    Tuesday, April 8, 2014 | 8:30 AM - 4:30 PM

    Translational Neuroscience in Psychiatry: Light at the End of the Tunnel

    Speakers: Dan V. Iosifescu (Icahn School of Medicine at Mount Sinai), Daniel C. Javitt (Columbia University and Nathan Kline Institute), John H. Krystal (Yale University), Andrew F. Leuchter (University of California, Los Angeles), Gregory Light (University of California, San Diego), Siva Digavalli (Bristol-Myers Squibb), Eva Redei (Northwestern University), Steven J. Siegel (University of Pennsylvania)

    Recent breakthrough insights from clinical studies are illuminating the neurobiology of psychiatric disorders. This symposium explores differences in sensory processing, imaging, and other biomarkers that may translate findings to animal models.

    Tuesday, March 25, 2014 | 12:00 PM - 4:00 PM

    Lung Cancer: Advances in Current Treatment Modalities and Patient Classification

    Speakers: Rolf Brekken (UT Southwestern), Jessica S. Donington (NYU Langone Medical Center), Balazs Halmos (Columbia University Medical Center), Roy S. Herbst (Yale School of Medicine), Suresh S. Ramalingam (Emory University)

    Recent treatment advances may improve lung cancer patient survival rates, as understanding genetic heterogeneity can improve trial patient selection. Hear updates on common mutations, intraoperative chemotherapy, and insights from clinical trials.

    Monday, March 24, 2014 | 8:00 AM - 5:00 PM

    World TB Day Symposium: Countdown to 2015

    Speakers: David Alland (Rutgers New Jersey Medical School), Stephanie Boisson-Dupuis (The Rockefeller University), Andrea M. Cooper (Trudeau Institute), Jerrold J. Ellner (Boston Medical Center), Daniel E. Everitt (TB Alliance), Michael S. Glickman (Memorial Sloan-Kettering Cancer Center), Kathleen A. McDonough (Wadsworth Center ), Steven A. Porcelli (Albert Einstein College of Medicine), Kyu Rhee (Weill Cornell Medical College), G. Marcela Rodriguez (Rutgers New Jersey Medical School), Padmini Salgame (Rutgers New Jersey Medical School), Marie Samanovic (NYU Langone Medical Center), Jessica C. Seeliger (Stony Brook University)

    TB is a curable infection that should be a disease of the past, yet a third of the world's population remains affected. Join us on World TB Day to explore scientific insights towards novel diagnostics, therapeutics and vaccine-related tools.

  • Publications 

    eBriefing

    Nanomedicines: Addressing the Scientific and Regulatory Gap

    Organizers: Raj Bawa (Bawa Biotech LLC; Rensselaer Polytechnic Institute), Scott E. McNeil (Nanotechnology Characterization Laboratory – Frederick National Laboratory for Cancer Research), Stefan Mühlebach (Vifor Pharma Ltd.; University of Basel, Switzerland), Melanie Brickman Stynes (The New York Academy of Sciences), and Melinda Miller (The New York Academy of Sciences)
    Keynote Speaker: Sally Tinkle (Science and Technology Policy Institute, IDA)

    This eBriefing explores regulatory challenges in the nascent field of nanomedicines.

    eBriefing

    Alzheimer's Disease Summit: The Path to 2025

    Keynote Speakers: Yuko Harayama (Council for Science and Technology Policy, Cabinet Office, Japan), Richard J. Hodes (National Institute on Aging, NIH), Jan M. Lundberg (Eli Lilly and Company), and Bengt Winblad (Karolinska Institute, Sweden)

    This eBriefing outlines a research agenda crafted by leading industry, academic, and government stakeholders to advance the goals of the U.S. National Alzheimer's Plan.

    Annals

    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents four scholarly reports: (1) Effects of Genetic, Processing, or Product Formulation Changes on Efficacy and Safety of Probiotics; (2) Probiotics and Prebiotics: Prospects for Public Health and Nutritional Recommendations; (3)Targeting Epigenetic Regulators for Cancer Therapy; and (4) Précis of Nutrition of Children and Women in Haiti: Analyses of Data from 1995 to 2012.

    Volume 1309

    eBriefing

    Dendritic Cell Therapies for Cancer: Biotech's Bumpy Road to the Market

    Organizers: John E. Hambor (Boehringer-Ingelheim Pharmaceuticals) and Jennifer Henry (The New York Academy of Sciences)

    Dendritic cells offer promise in the development of cancer vaccines.

  • Podcasts

    Podcast
    April 2, 2010

    More than a Yogurt Cup

    Delve into the world of prebiotic and probiotic science. We talk to three people in the field and learn why keeping the good microbes in our bodies happy means a lot for health.

    Download (14 MB, 00:21:21)
    Podcast
    January 15, 2010

    Feeling the Light

    Researchers at Harvard have discovered why the headaches of some migraine sufferers worsen when the person is exposed to light. Rami Burstein, the study's senior author, explains what's happening in the brain, and how they made the breakthrough.

    Download (15 MB, 00:22:48)
    Podcast
    December 18, 2009

    No Small Matter

    We sit down with science photographer Felice Frankel and nanotechnology pioneer and Harvard chemist George Whitesides to hear about their new book on nanoscience, No Small Matter.

    Download (11 MB, 00:18:04)
    Podcast
    October 16, 2009

    Looking for the Key in P53

    Visit the lab of Hunter College's Jill Bargonetti, a biologist researching cancer. Her team studies P53, a natural tumor-suppressor protein found in our bodies with a Dr. Jekyll and Mr. Hyde personality.

    Download (11 MB, 00:17:20)
  • Webinar Archives

    Webinar Archive
    February 23, 2010

    Metabotropic Glutamate Receptors: Translation from Discovery to Clinical Trials

    Researchers met to discuss advances in basic and translational research on metabotropic glutamate receptors, which are promising targets in drug discovery for CNS diseases and other illnesses.

    Webinar Archive
    October 27, 2009

    Is Alzheimer's Disease Type 3 Diabetes?

    What is the connection between dysregulated neuronal insulin signaling and Alzheimer's disease? In a recent Academy webinar, some researchers argued that the neurodegenerative disease should be considered a type of diabetes.

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.