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  • Drug Development

  • Featured Event

    Green Buildings and Health: From the Lab to the Real World

    Wednesday, December 14, 2016 | 6:00 PM - 8:30 PM
    The New York Academy of Sciences

    Researchers at Harvard T.H. Chan School of Public Health and SUNY Upstate Medical University present the results of a new study showing that employees in high-performing, green-certified buildings had higher cognitive function test scores than those in similarly high-performing buildings that were not green certified, even after controlling for other potential explanatory factors.

  • Events 

    Tuesday, December 6, 2016 | 9:00 AM - 5:00 PM

    Alzheimer's Disease as a Neurovascular Inflammatory Disorder

    Speakers: Katerina Akassoglou (University of California, San Francisco), Robert Dempsey (University of Wisconsin), Paula Grammas (University of Rhode Island), Steven Greenberg (Massachusetts General Hospital and Harvard Medical School), Jaime Grutzendler (Yale University), Costantino Iadecola (Weill Cornell Medicine), Jeffrey Iliff (Oregon Health & Science University), Berislav Zlokovic (Keck School of Medicine of USC), Heather Snyder (Alzheimer's Association), Zorina Galis (NIH)

    This symposium will highlight basic research and clinical science elucidating the mechanisms underlying the contribution of inflammatory pathways to vascular cognitive impairment and dementia (VCID).

    Wednesday, March 1, 2017 | 9:00 AM - 5:00 PM

    Quantitative Approaches in Immuno-Oncology

    Keynote Speaker: Harlan Robins (Fred Hutchinson Cancer Research Center)

    This symposium will explore the emerging field of quantitative immuno-oncology, covering the breadth of scientific topics and methods needed to quantify interactions between tumors and the immune system.

    Monday, March 13, 2017 | 8:30 AM - 6:00 PM

    Targeting Tau in Alzheimer's Disease and Related Disorders

    Speakers: Michael G. Agadjanyan (The Institute for Molecular Medicine), Bernardino Ghetti, (Indiana University), Andreas Muhs (AC Immune SA), Michal Novák (AXON Neuroscience SE), Einar M. Sigurdsson (NYU School of Medicine), Henrik Zetterberg (University of Gothenburg, Sweden), and Khalid Iqbal (New York State Institute for Basic Research)

    This event will cover the translational potential of immunotherapy for tauopathies, reviewing the pre-clinical and clinical development of several tau immunotherapy programs that exemplify this emerging therapeutic approach.

    March 15 - 16, 2017

    The Need to Accelerate Therapeutic Development — Must Randomized Controlled Trials Give Way?

    Experience a public-facing dialogue exploring the nuanced ethical and scientific rationale behind randomized controlled clinical trials, accelerated alternatives, and the implications of these discussions on drug approval and patient interests.

    Tuesday, March 21, 2017 | 12:00 PM - 5:00 PM

    Exosomes in the CNS

    Speakers: Tsuneya Ikezu (Boston University School of Medicine), David Issadore (University of Pennsylvania), Xandra Breakefield (Massachusetts General Hospital), Efrat Levy (NYU School of Medicine), and Andrew West (The University of Alabama at Birmingham)

    In this symposium we will explore the contribution of extracellular vesicles to pathological processes underling neurodegenerative disorders, and the appeal of exosomes as biomarkers and targets for the development of novel therapeutics.

  • Past Events

    Tuesday, November 15, 2016 | 9:00 AM - 4:30 PM

    Mucosal Healing of the Intestinal Epithelial Barrier

    Speakers: Thaddeus Stappenbeck (Washington University School of Medicine), Declan F. McCole (University of California Riverside), Jerrold R. Turner (Brigham and Women's Hospital), Linda G. Griffith (MIT), Tim Denning (Georgia State University), and Alan Hanash (Memorial Sloan Kettering Cancer Center)

    This symposium will evaluate emerging research investigating the benefits of achieving mucosal healing in the treatment of intestinal disorders.

    Thursday, November 10, 2016 | 8:00 AM - 6:00 PM

    Epigenetics in Cancer: Translational Medicine Approaches

    Keynote Speaker: Christopher E. Mason (Weill Cornell Medical College)

    This conference will explore novel target and validation strategies, translational approaches to assess predictive and response biomarkers, resistance mechanisms, and combination strategies for targeting epigenetic susceptibilities in cancer.

    Wednesday, November 9, 2016 | 8:30 AM - 5:15 PM

    Equivalence of Complex Drug Products: Scientific and Regulatory Challenges

    Keynote Speaker: Lawrence D. Mayer (Jazz Pharmaceuticals)

    Explore approaches for complex drug development and regulation, outstanding challenges in the assessment of complex drug equivalence, consequences for product interchangeability, and compare biological and non-biological complex drug families.

    Thursday, November 3, 2016 | 9:00 AM - 5:00 PM

    Microbial Influences in Cardio–Metabolic Diseases

    Speakers: Henrik Bjørn Nielsen (Clinical-Microbiomics A/S), Martin J. Blaser (New York University Langone Medical Center), Patrice D. Cani (Universite Catholique de Louvain, LDRI), Rachel Carmody (Harvard University), Stanley L. Hazen (Cleveland Clinic), Gerald I. Shulman (Yale University School of Medicine), Marion Soto (Joslin Diabetes Center, Harvard Medical School), and Dan Winer (University of Toronto)

    The microbiome is emerging as an important regulator of health, and disease well beyond the digestive tract. This symposium will highlight recent research innovations and therapeutic applications from the microbiome with a focus on metabolic disease.

  • Publications 

    eBriefing

    Surgery and Cognition: Delirium, Cognitive Decline, and Opportunities to Protect the Brain

    Featuring: Sharon Inouye, MD, MPH (Harvard Medical School)

    Surgery helps millions of Americans overcome illness to live longer, healthier lives. Yet surgery can lead to delirium, cognitive decline, and perhaps even a higher long-term risk of dementia for many patients, a risk that is poorly understood and often under-recognized in the clinic. With numerous factors—including age—contributing to each patient's level of risk, what are the challenges and opportunities to create biomarkers and therapeutics for those who are most vulnerable?

    Annals

    Special Issue: Musculoskeletal Repair and Regeneration

    Edited by Hui B. Sun (Albert Einstein College of Medicine)

    The papers in this Annals issue explore novel musculoskeletal repair and regeneration strategies that could be translated to clinical treatment of rotator cuff injuries, osteoarthritis, and other bone and cartilage diseases.

    Volume 1383

    Annals

    Special Issue: Countermeasures Against Chemical Threats II

    Edited by Jeffrey D. Laskin (Rutgers University School of Public Health)

    Discussions of various countermeasures to chemical threats.

    eBriefing

    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Centre, University of Cambridge, UK) and Craig B. Thompson (Memorial Sloan Kettering Cancer Center)

    This eBriefing covers the latest research on pediatric cancers.