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  • Genetics & Genomics

  • Events 

    Tuesday, March 15, 2016 | 8:30 AM - 4:30 PM

    Advances in Human Microbiome Science: Gut-Brain Interaction

    Speakers: Premysl Bercik (McMaster University Medical Centre), John F Cryan (University College Cork), Ted Dinan (University College Cork), Emeran Mayer (David Geffen School of Medicine, UCLA), Sarkis Mazmanian (California Institute of Technology), Vassilis Pachnis, MD (The Francis Crick Institute), Robert Yolken (John Hopkins School of Medicine)

    The gut microbiome is emerging as an important regulator of brain development, brain health, and disease. This symposium will highlight recent research innovations and therapeutic applications from the microbiome with a focus on CNS health.

    March 30 - April 1, 2016

    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Center, University of Cambridge), Craig B. Thompson (Memorial Sloan Kettering Cancer Center)
    Speakers: Scott Armstrong (Memorial Sloan Kettering Cancer Center), Eric Bouffet (The Hospital for Sick Children, Toronto), Stefan Burdach (Technical University of Munich, Germany), Michael Dyer (St. Jude Children's Research Hospital, Howard Hughes Medical Institute), Nancy Goodman (Kids V Cancer), Lee J. Helman (National Cancer Institute, National Institutes of Health), Nada Jabado (McGill University), Katherine A. Janeway (Dana-Farber Cancer Center, Harvard Medical School), Michael Jensen (Seattle Children's Hospital), Javed Khan (National Cancer Institute, National Institutes of Health), Andrew Kung (Columbia University Medical Center), A. Thomas Look (Dana-Farber Cancer Center, Harvard University), David C. Lyden (Weill Cornell Medical College), Elizabeth Maher (University of Texas Southwestern Medical Center), David Malkin (The Hospital for Sick Children), John Maris (The Children's Hospital of Philadelphia and the University of Pennsylvania), Yael Mossé (The Children’s Hospital of Philadelphia), Kathy Pritchard-Jones (Great Ormond Street Hospital for Children NHS Foundation Trust and University College London), Charles W.M. Roberts (St. Jude Children's Research Hospital), Michel Sadelain (Memorial Sloan Kettering Cancer Center), Paul M. Sondel (University of Wisconsin School of Medicine and Public Health), Poul H. Sorensen (University of British Columbia), Kimberly Stegmaier (Dana-Farber Cancer Institute), Michael D. Taylor (The Hospital for Sick Children, University of Toronto), Matthew Vander Heiden (The Koch Institute, Massachusetts Institute of Technology), Robert Wechsler-Reya (Sanford Burnham Prebys Institute of Medical Discovery)

    Discover the latest on pediatric cancers from leading experts, including etiological differences between pediatric and adult cancers, epigenetics, mechanisms of metastasis and disease recurrence, risk factors, diagnostics, and novel treatment approaches.

    Monday, April 4, 2016 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group

    Speakers: Titia deLange (The Rockefeller University), David Jeruzalmi (The City College of New York - CUNY), Ken Marians (Memorial Sloan Kettering Cancer Center), Duncan Smith (New York University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    April 13 - 14, 2016

    Disease Drivers of Aging: 2016 Advances in Geroscience Summit

    Speakers: Domenico Accili (Columbia University), Timothy Ahles (Memorial Sloan Kettering Cancer Center), Kathryn Anastos (Albert Einstein College of Medicine), Nir Barzilai (Albert Einstein College of Medicine), James Becker (University of Pittsburgh), Caroline Blaum (New York University), Judith Campisi (Buck Institute for Research on Aging), Harvey J. Cohen (Duke University), Steven Deeks (AIDS Research Institute; University of California, San Francisco), Wendy Demark-Wahnefried (University of Alabama at Birmingham), Elissa Epel (University of California, San Francisco), Kristine Erlandson (University of Colorado), Claudia Gravekamp (Albert Einstein College of Medicine), Jeffrey Halter (University of Michigan), Kevin High (Wake Forest University), Peter Hunt (University of California, San Francisco), Arti Hurria (City of Hope National Medical Center), Beth Jamieson (University of California, Los Angeles), C. Ronald Kahn (Joslin Diabetes Center), Balakuntalam Kasinath (Barshop Institute for Longevity and Aging Studies; University of Texas Health Science Center), Gretchen Neigh (Emory University), Rosario Scalia (Temple University), Jan van Deursen (Mayo Clinic)

    Explore how chronic diseases — specifically HIV/AIDS, diabetes, and cancer — can affect the seven mechanistic pillars of aging.

    Tuesday, April 26, 2016 | 9:00 AM - 5:00 PM

    Solute Carrier Proteins: Unlocking the Gene-Family for Effective Therapies

    Speakers: Dax Fu (John Hopkins School of Medicine), Kathleen M. Giacomini (University of California, San Francisco), Matthias A. Hediger (University of Bern), Avner Schlessinger (Icahn School of Medicine at Mount Sinai), Giulio Superti-Furga (Austrian Academy of Sciences), Ming Zhou (Baylor College of Medicine)

    Solute Carrier Proteins are an untapped resource for drug discovery. This event will discuss breakthroughs in structural biology, cell engineering and metabolomics that hold the promise of "unlocking" this gene family.

  • Past Events

    Monday, February 1, 2016 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group

    Speakers: Alberto Ciccia (Columbia University Medical Center), Maria Jasin (Memorial Sloan Kettering Cancer Center), Jun Hyun Kim (Memorial Sloan Kettering Cancer Center), Alexandra Pinzaru (NYU School of Medicine), Richard Pomerantz (Temple University), Patrick Sung (Yale University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Monday, December 7, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group

    Speakers: Jean Gautier (Columbia University Medical Center), Olga A. Guryanova (Weill Cornell Medical College), Jaspreet S. Khurana (Princeton University), Hannah Klein (NYU Langone Medical Center), Neal Lue (Weill-Cornell Medical College), Dirk Remus (Memorial Sloan Kettering Cancer Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, October 27, 2015 | 8:00 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras J. Bauer (Boehringer Ingelheim USA), Myles Fennell (Memorial Sloan-Kettering Cancer Center), Michael R. Jackson (Sanford Burnham Prebys Medical Discovery Institute), Jonathan A. Lee (Eli Lilly), Martin Main (AstraZeneca), Friedrich Metzger (F. Hoffmann-La Roche Ltd), Bruce A. Posner (University of Texas, Southwestern Medical Center), Yao Shen (Columbia University), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Susanne Swalley (Novartis Institutes for Biomedical Research), Jitao David Zhang (F. Hoffmann-La Roche Ltd.)

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

    October 18 - 22, 2015

    Tenth Cooley's Anemia Symposium

    Keynote Speakers: Maria Domenica Cappellini (University of Milan) and Stuart H. Orkin (Boston Children's Hospital and Dana-Farber Cancer Institute)
    Speakers: Emanuele Angelucci (Cancer Hospital "Armando Businco," Cagliari), Jodie L. Babitt (Massachusetts General Hospital), Jonathan M. Barasch (Columbia University), Daniel E. Bauer (Boston Children's Hospital; Dana-Farber Cancer Institute; Harvard Medical School), Sunil Bhandari (Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School), Caterina Borgna-Pignatti (University of Ferrara), Farid Boulad (Memorial Sloan-Kettering Cancer Center), Marina Cavazzana-Calvo (Hospital Necker, University Paris Descartes), David H.K. Chui (Boston University School of Medicine), Thomas D. Coates (Childrens Hospital Los Angeles, University of Southern California Keck School of Medicine), Ann Dean (National Institutes of Health), David Dinan (Nemours Children’s Hospital), Alexander (Hal) Drakesmith (Radcliffe Department of Medicine, University of Oxford), Kathleen Durst (Cooley's Anemia Foundation), Giuliana Ferrari (San Raffaele-Telethon Institute for Gene Therapy), Steven Flamm (Northwestern Medical Center), Mark D. Fleming (Boston Children's Hospital), Ellen B. Fung (UCSF Benioff Children's Hospital Oakland), Andrea Giusti (Galliera Hospital), Olivier Hermine (Hospital Necker, University Paris Descartes), Doug Higgs (University of Oxford), Eldad Arie Hod (Columbia University), Janet L. Kwiatkowski (The Children's Hospital of Philadelphia; Perelman School of Medicine, University of Pennsylvania), Ashutosh (Ash) Lal (University of California San Francisco Benioff Children’s Hospital Oakland), Roberto Machado (University of Illinois College of Medicine), Takahiro Maeda (Brigham and Women's Hospital), Punam Malik (Cincinnati Children’s Hospital), Jeffery L. Miller (National Institute of Diabetes and Digestive and Kidney Diseases), David G. Nathan (Dana-Farber Cancer Institute), Elizabeth (Ella) Nemeth (University of California, Los Angeles), Ellis Neufeld (Boston Children's Hospital), Arthur Nienhuis (St. Jude Children's Research Hospital), Dudley Pennell (Imperial College London), Antonio Piga (Torino University), John Porter (University College London Hospitals), Scott Reeder (University of Wisconsin School of Medicine and Public Health), Stefano Rivella (Children's Hospital of Philadelphia), Thomas M. Ryan (The University of Alabama at Birmingham), Vijay Sankaran (Boston Children's Hospital and Dana-Farber Cancer Institute), Shalini Shenoy (St. Louis Children's Hospital), Ali Taher (American University of Beirut Medical Center), Swee Lay Thein, John F. Tisdale (National Heart, Lung, and Blood Institute), Suzy V. Torti (University of Connecticut Health Center), Tim M. Townes (The University of Alabama at Birmingham), Marsha J. Treadwell (Children's Hospital Oakland), Vip Viprakasit (Siriraj Hospital, Mahidol University), John C. Wood (Children's Hospital Los Angeles)

    Global experts explore the biology of globin gene regulation and fetal hemoglobin induction; stem cell transplant, gene therapy strategies, and gene editing; and clinical issues in thalassemia treatment and imaging.

  • Publications 

    eBriefing

    Phenotypic and Biomarker-based Drug Discovery

    Organizers: Michael Foley (Tri-Institutional Therapeutics Discovery Institute), Ralph Garippa (Memorial Sloan-Kettering Cancer Center), David Mark (F. Hoffmann-La Roche), Lorenz Mayr (Astra Zeneca), John Moffat (Genentech), Marco Prunotto (F. Hoffmann-La Roche), and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing considers the merits of phenotypic drug discovery, which is experiencing a renaissance of interest. The method aims to find therapeutically useful compounds by screening thousands of substances for functional cellular outputs.

    eBriefing

    Advances in Human Microbiome Science: Intestinal Diseases

    Organizers: Mercedes Beyna (Pfizer), John Hambor (Boehringer Ingelheim), Nilufer Seth (Pfizer), Erick Young (Boehringer Ingelheim), and Sonya Dougal (The New York Academy of Sciences)
    Keynote Speaker: Stanislav Dusko Ehrlich (French National Institute for Agricultural Research; King's College London)

    This eBriefing focuses on the causal relationships between gut microbiota and intestinal health and disease.

    Annals

    B-1 Cell Development and Function

    Edited by Thomas L. Rothstein (The Feinstein Institute for Medical Research), Leonore A. Herzenberg (Stanford University School of Medicine), Nichol E. Holodick (The Feinstein Institute for Medical Research), and Eliver Ghosn (Stanford University School of Medicine)

    These papers discuss the physiological role of a unique subpopulation of B lymphocytes called B-1 cells.

    Annals

    The Year in Evolutionary Biology

    Edited by Timothy A. Mousseau (University of South Carolina) and Charles W. Fox (University of Kentucky)

    The seventh installment of this Annals series presents scholarly reviews on current topics in evolutionary biology.

    Volume 1360