• Biochemistry, Biophysics & Structural Biology

  • Events 

    Tuesday, October 27, 2015 | 8:00 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras J. Bauer (Boehringer Ingelheim USA), Michael R. Jackson (Sanford Burnham Prebys Medical Discovery Institute), Jonathan A. Lee (Eli Lilly), Martin Main (AstraZeneca), Friedrich Metzger (F. Hoffmann-La Roche Ltd), Bruce A. Posner (University of Texas, Southwestern Medical Center), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Susanne Swalley (Novartis Institutes for Biomedical Research), Jitao David Zhang (F. Hoffmann-La Roche Ltd.)

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

    Friday, December 4, 2015 | 8:30 AM - 6:00 PM

    Managing Disease-Related Lean Body Mass Loss through Clinical and Nutrition Interventions

    Speakers: Melissa J. Benton (University of Colorado at Colorado Springs), David Evans (The Ohio State University), Gordon Jensen (The Pennsylvania State University), Robert Martindale (Oregon Health & Science University Healthcare), Peter A. McCullough (Dallas Baylor Heart and Vascular Hospital), Gerard Mullin (Johns Hopkins Medicine), Dennis H. Sullivan (University of Arkansas), Paul Wischmeyer (University of Colorado School of Medicine)

    Lean Body Mass Loss Clinical and Nutrition Interventions

    Tuesday, December 8, 2015 | 8:30 AM - 5:00 PM

    GLP-1 Treatment for Metabolic Disease and Beyond

    Speakers: David D'Alessio (Duke University), Richard DiMarchi (Indiana University), Keld Fosgerau (Zealand Pharma), Matthew Hayes (Perelman School of Medicine, University of Pennsylvania), George Holz (State University of New York), Lotte Knudsen (Novo Nordisk), Patrick Sexton (Monash University), Konrad Talbot (Cedars-Sinai Medical Center), Beat Jucker (GlaxoSmithKline)

    GLP-1 receptor agonists have improved treatment options in type 2 diabetes, although realizing their promise in other areas remains challenging. This symposium highlights preclinical and clinical breakthroughs and opportunities for drug development.

  • Past Events

    Monday, October 5, 2015 | 1:30 PM - 5:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Roger Greenberg (University of Pennsylvania), Andreas Hochwagen (New York University), Megan King (Yale University), Rodney Rothstein (Columbia University), Eleni Mimitou (Memorial Sloan Kettering Cancer Center), Pedro Rocha (NYU Langone Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, September 29, 2015 | 12:00 PM - 5:00 PM

    Visualizing Cellular Messengers

    Speakers: Samie R. Jaffrey (Weill Cornell Medical College), Amy E. Palmer (University of Colorado)

    This symposium features state of the art chemical tools and imaging strategies for metal ions, redox signaling species, and metabolites in the cell, cellular delivery and targeting approaches, and their application to studying life processes.

    Friday, September 18, 2015 | 8:30 AM - 5:00 PM

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Speakers: George S. Bloom (University of Virginia), Peter Davies (Feinstein Institute for Medical Research), Marc I. Diamond (University of Texas Southwestern Medical Center), Michael Hutton (Eli Lilly and Company), Khalid Iqbal (New York State Institute for Basic Research in Developmental Disabilities), Magdalena J. Kiprowska (Hunter College and Graduate Center, CUNY), Hartmuth C. Kolb (Johnson & Johnson, Janssen R&D), Nicole Leclerc (Université de Montréal), Kun Ping Lu (Harvard Medical School), Natura Myeku (Taub Institute for Alzheimer's Disease Research, Columbia University), Richard M. Ransohoff (Biogen)

    Speakers at this symposium will address novel tau-centered mechanisms of neurodegeneration and new therapeutic approaches for many devastating neurological disorders.

    Wednesday, September 16, 2015 | 8:00 AM - 2:15 PM

    From Tumor Suppressors to Oncogenic Dynamics: The 2015 Dr. Paul Janssen Award Symposium

    Award Winner Bert Vogelstein (Johns Hopkins School of Medicine; Howard Hughes Medical Institute)

    This symposium will honor Dr. Bert Vogelstein, the recipient of the 2015 Dr. Paul Janssen Award for Biomedical Research, in recognition of his role in characterizing the underlying mechanisms of cancer. Symposium registration is free. Advance registration is required.

  • Publications 


    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents discussions ofnutrition and the science of disease prevention; designing optogenetically controlled RNA for regulating biological systems; and how ion channels sense mechanical force

    Volume 1352


    Click Chemistry in Biology and Medicine

    Organizers: Peng Wu (Albert Einstein College of Medicine) and Jennifer Henry (formerly at The New York Academy of Sciences)
    Keynote Speakers: Jim Paulson (Scripps Research Institute) and K. Barry Sharpless (Scripps Research Institute)

    This eBriefing explores recent developments in the search for click reactions with applications in disease diagnosis and therapy.


    Elucidating GPCR Functional Selectivity for Drug Development

    Organizers: John A. Allen (Pfizer), Mercedes Beyna (Pfizer), Bryan L. Roth (University of North Carolina School of Medicine), and Jennifer Henry (formerly at The New York Academy of Sciences)

    This eBriefing looks at how to exploit biased ligand signaling at GPCRs to improve therapeutics for cardiovascular and CNS disorders.


    From Bacterial Immunity to Genome Editing: The 2014 Dr. Paul Janssen Award Symposium

    Featured Speakers: Emmanuelle Charpentier (Helmholtz Centre for Infection Research, Hannover Medical School, Germany; Umeå University, Sweden) and Jennifer Doudna (University of California, Berkeley; Howard Hughes Medical Institute)

    This eBriefing features Emmanuelle Charpentier and Jennifer Doudna, recipients of the 2014 Dr. Paul Janssen Award for Biomedical Research for their role in understanding and adapting the CRISPR/Cas system for genome editing.

  • Podcasts

    Understanding nutrition's impact on health requires an intricate knowledge of all the different systems within the human body. Learn how a systems approach to nutrition could change the field.

    Download (44 MB, 32:02)

    A recent conference held at the Academy asked a downright outrageous question: Can dementia be prevented by making changes to your diet? In this podcast we look at what the answers might be.

    Download (87 MB, 38:11)

    In the second of a two-part series, experts look at the links between health and nutrition. They examine everything from how nutrition impacts hospital stays, to cancer and aging, to developing food science innovations, and improving diet.

    Download (45 MB, 19:56)
  • Webinar Archives

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.