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  • Biochemistry, Biophysics & Structural Biology

  • Events 

    Thursday, September 11, 2014 | 8:00 AM - 2:00 PM

    From Bacterial Immunity to Genome Editing: The 2014 Dr. Paul Janssen Award Symposium

    Featuring Award Winners: Emmanuelle Charpentier (Helmholtz Centre for Infection Research) and Jennifer Doudna (Howard Hughes Medical Institute/University of California, Berkeley)

    Honor Drs. Emmanuelle Charpentier and Jennifer Doudna, recipients of the 2014 Dr. Paul Janssen Award for Biomedical Research.

    Monday, September 15, 2014 | 12:00 PM - 4:00 PM

    Click Chemistry in Biology and Medicine: New Developments and Strategies

    Keynote Speakers: Jim Paulson (The Scripps Research Institute), K. Barry Sharpless (The Scripps Research Institute)
    Speakers: Yimon Aye (Cornell University), David A. Spiegel (Yale University), Mingxuan Wu (Princeton University), Peng Wu (Albert Einstein College of Medicine)

    Click chemistry offers a reliable method for discovering chemical connectivity, with great potential in drug discovery and biomedical research. This symposium explores recent developments that offer new technologies for disease diagnosis and therapy.

    Tuesday, October 28, 2014 | 8:30 AM - 5:00 PM

    Pharmacologic Resolution of Inflammation as a Novel Therapeutic Approach

    Speaker: Michael S. Conte (University of California-San Francisco, San Francisco, CA), Milan Fiala (David Geffen School of Medicine at UCLA, Los Angeles, CA), Gabrielle Fredman (Columbia University, New York, NY), Bruce Levy (Harvard University, Brigham and Women's Hospital, Boston, MA), Dipak Panigrahy (Beth Israel Deaconess Medical Center, Boston, MA), Mauro Perretti (William Harvey Research Institute, London, UK), Charles N. Serhan (Harvard University, New York, NY), Patricia J. Sime (University of Rochester School of Medicine, Rochester, NY), Rudy Tanzi (Massachusetts General Hospital, Charlestown, MA)

    Uncontrolled, chronic inflammation plays a key role in the progression of many diseases, and elucidation of biochemical pathways provides novel targets. This symposium reviews discoveries, approaches and opportunities for treatment and prevention.

    Monday, November 3, 2014 | 8:00 AM - 4:30 PM

    Gene Network Changes in Alzheimer's Disease: Potential Points for Therapeutic Intervention

    Speakers: Erik W.G.M. Boddeke (University Medical Center Groningen, The Netherlands), Oleg Butovsky (Brigham and Women's Hospital and Harvard Medical School, Boston, MA), Philip L. De Jager (Harvard University and Brigham and Women's Hospital, Boston, MA), Joseph El Khoury (Massachusetts General Hospital and Harvard Medical School, Boston, MA), Miriam Merad (Icahn School of Medicine at Mt. Sinai, New York, NY), Michael C. Oldham (University of California, San Francisco, San Francisco, CA), Bin Zhang (Icahn School of Medicine at Mt. Sinai, New York, NY)

    Next generation sequencing of Alzheimer’s disease (AD) progression reveals gene networks within microglial pathways. This symposium focuses on microglia biology, molecular signatures specific to microglial phenotypes, and phenotype modulation.

  • Past Events

    Tuesday, June 3, 2014 | 9:30 AM - 2:30 PM

    Chemical Biology Discussion Group Year-End Symposium

    Keynote Speaker: Michael Marletta (The Scripps Research Institute)

    The Chemical Biology Discussion Group brings together chemists and biologists interested in discussing the latest breakthroughs. The year-end meeting features keynote speaker Michael Marletta of the Scripps Research Institute and a poster session.

    Monday, June 2, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Keynote Speaker: Julie Cooper (National Cancer Institute, NIH)
    Speakers: Akiko Inagaki (Petrini Lab, Memorial Sloan-Kettering Cancer Center), Isabel Lam (Keeney Lab, Memorial Sloan-Kettering Cancer Center), Dongxu Lin (King Lab, Yale University), Mahesh Ramamoorthy (Smith Lab, NYU Langone Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Friday, May 9, 2014 | 8:00 AM - 4:00 PM

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Speakers: Carmela R. Abraham (Boston University School of Medicine), Eric H. Baehrecke (University of Massachusetts Medical School), Nir Barzilai (Albert Einstein College of Medicine), Jerry R. Colca (Metabolic Solutions Development Company), Brendan D. Manning (Harvard School of Public Health), Beth Stevens (Harvard Medical School), D. Martin Watterson (Northwestern University Feinberg School of Medicine), Haung Yu (Columbia University), Jeffrey W. Kelly (The Scripps Research Institute), Richard I. Morimoto (Northwestern University)

    Age is the major risk factor for Alzheimer's disease, and key pathways in aging biology offer targets for novel drugs. Explore recent advances in the science of aging and innovative drug discovery for Alzheimer's and other neurodegenerative diseases.

    Thursday, April 10, 2014 | 8:30 AM - 4:30 PM

    Mitochondria, Metabolism and Disease

    Speakers: Robert Balaban (National Heart, Lung, and Blood Institute, NIH), Robert Bao (Massachusetts General Hospital), Salvatore DiMauro (Columbia University Medical Center), Steven Gross (Weill Cornell Medical College), Costas A. Lyssiotis (Weill Cornell Medical College), Jared Rutter (University of Utah School of Medicine), Hazel H. Szeto (Weill Cornell Medical College), Benjamin P. Tu (UT Southwestern Medical Center)

    Damage to mitochondria, which are critical in metabolism, underlies a wide range of human diseases, making them an important therapeutic target. Researchers aim to characterize and cure diseases arising from aberrant mitochondrial metabolism.

  • Publications 

    eBriefing

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation), Kevin J. Lee (Lawrence Ellison Foundation), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing explores advances in the science of aging and in drug discovery for Alzheimer's and other neurodegenerative diseases.

    eBriefing

    Nanomedicines: Addressing the Scientific and Regulatory Gap

    Organizers: Raj Bawa (Bawa Biotech LLC; Rensselaer Polytechnic Institute), Scott E. McNeil (Nanotechnology Characterization Laboratory – Frederick National Laboratory for Cancer Research), Stefan Mühlebach (Vifor Pharma Ltd.; University of Basel, Switzerland), Melanie Brickman Stynes (The New York Academy of Sciences), and Melinda Miller (The New York Academy of Sciences)
    Keynote Speaker: Sally Tinkle (Science and Technology Policy Institute, IDA)

    This eBriefing explores regulatory challenges in the nascent field of nanomedicines.

    eBriefing

    The Microbiome in Health, Disease, and Therapeutics: Bugs, Guts, and Drugs

    Organizers: Mercedes Beyna (Pfizer), Robert Martone (Covance Biomarker Center of Excellence), Nilufer Seth (Pfizer), Richard Snyder (Covance Biomarker Center of Excellence), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing looks at how symbioses between humans and the gut microbiome impact drug metabolism, development, and a variety of disease states.

    eBriefing

    Understanding Somatosensation and Pain: The 2013 Dr. Paul Janssen Award Symposium

    Featured Speaker: David Julius (University of California, San Francisco)

    This eBriefing features David Julius, the recipient of the 2013 Dr. Paul Janssen Award for Biomedical Research for his role in discovering a mechanism for nociception and thermosensation. Recent research on pain is also described.

  • Podcasts

    Podcast
    January 1, 2010

    The Science of Sushi

    Danish biophysicist Ole Mouritsen also happens to be an expert on, and lover of sushi. This week, we talk to him about his new book, Sushi: Food for the Eye, the Body, and the Soul.

    Download (9 MB, 00:14:52)
    Podcast
    December 18, 2009

    No Small Matter

    We sit down with science photographer Felice Frankel and nanotechnology pioneer and Harvard chemist George Whitesides to hear about their new book on nanoscience, No Small Matter.

    Download (11 MB, 00:18:04)
  • Webinar Archives

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.