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  • Biochemistry, Biophysics & Structural Biology

  • Events 

    Tuesday, April 26, 2016 | 9:00 AM - 5:00 PM

    Solute Carrier Proteins: Unlocking the Gene-Family for Effective Therapies

    Speakers: Dax Fu (John Hopkins School of Medicine), Kathleen M. Giacomini (University of California San Francisco), Matthias A. Hediger (University of Bern), Avner Schlessinger (Icahn School of Medicine at Mount Sinai), Giulio Superti-Furga (Austrian Academy of Sciences), Ming Zhou (Baylor College of Medicine)

    Solute Carrier Proteins are an untapped resource for drug discovery. This event will discuss breakthroughs in structural biology, cell engineering and metabolomics that hold the promise of "unlocking" this gene family.

  • Past Events

    Thursday, January 21, 2016 | 8:30 AM - 5:30 PM

    The New York Structural Biology Discussion Group 11th Winter Meeting

    Speakers: David Eliezer (Weill Cornell Medical College), Andras Fiser (Albert Einstein College of Medicine), Ruben Gonzalez (Columbia University), Balasubramanian Harish (Princeton University), Ron Koder (City College of New York), Filippo Mancia (Columbia University), Smita Patel (Rutgers University), Stefano Piana-Agostinetti (D.E. Shaw Research), Betsy Speltz (Yale University), Corey Wilson (Yale University)

    The New York Area Structural Biology Discussion Group convenes twice annually and presents talks and poster sessions from graduate students, postdocs, and laboratory heads.

    Tuesday, December 8, 2015 | 8:30 AM - 4:45 PM

    GLP-1 Treatment for Diabetes and Beyond

    Speakers: David D'Alessio (Duke University), Richard DiMarchi (Indiana University), Jean-Philippe Fortin (Pfizer Global), Keld Fosgerau (Zealand Pharma A/S), Matthew R. Hayes (Perelman School of Medicine, University of Pennsylvania), George G. Holz (State University of New York), Beat Jucker (GlaxoSmithKline), Dong Seok Kim (National Institute on Aging / Peptron Inc), Lotte Bjerre Knudsen (Novo Nordisk), Patrick M. Sexton (Monash University), Konrad Talbot (Cedars-Sinai Medical Center)

    GLP-1 receptor agonists have improved treatment options in type 2 diabetes, although realizing their promise in other areas remains challenging. This symposium highlights preclinical and clinical breakthroughs and opportunities for drug development.

    Friday, December 4, 2015 | 8:30 AM - 6:00 PM

    Managing Disease-Related Lean Body Mass Loss through Clinical and Nutrition Interventions

    Speakers: Melissa J. Benton (University of Colorado at Colorado Springs), David Evans (The Ohio State University), Gordon Jensen (The Pennsylvania State University), Robert Martindale (Oregon Health & Science University Healthcare), Peter A. McCullough (Dallas Baylor Heart and Vascular Hospital), Gerard Mullin (Johns Hopkins Medicine), Dennis H. Sullivan (University of Arkansas), Paul Wischmeyer (University of Colorado School of Medicine)

    Lean Body Mass Loss Clinical and Nutrition Interventions

    Tuesday, October 27, 2015 | 8:00 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras J. Bauer (Boehringer Ingelheim USA), Myles Fennell (Memorial Sloan-Kettering Cancer Center), Michael R. Jackson (Sanford Burnham Prebys Medical Discovery Institute), Jonathan A. Lee (Eli Lilly), Martin Main (AstraZeneca), Friedrich Metzger (F. Hoffmann-La Roche Ltd), Bruce A. Posner (University of Texas, Southwestern Medical Center), Yao Shen (Columbia University), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Susanne Swalley (Novartis Institutes for Biomedical Research), Jitao David Zhang (F. Hoffmann-La Roche Ltd.)

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

  • Publications 

    eBriefing

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Organizers: Robert Martone (St. Jude Children's Research Hospital) and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing explores tau-related mechanisms of neurodegeneration and emerging therapeutic strategies focused on tau.

    eBriefing

    Phenotypic and Biomarker-based Drug Discovery

    Organizers: Michael Foley (Tri-Institutional Therapeutics Discovery Institute), Ralph Garippa (Memorial Sloan-Kettering Cancer Center), David Mark (F. Hoffmann-La Roche), Lorenz Mayr (Astra Zeneca), John Moffat (Genentech), Marco Prunotto (F. Hoffmann-La Roche), and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing considers the merits of phenotypic drug discovery, which is experiencing a renaissance of interest. The method aims to find therapeutically useful compounds by screening thousands of substances for functional cellular outputs.

    eBriefing

    From Tumor Suppressors to Oncogenic Dynamics: The 2015 Dr. Paul Janssen Award Symposium

    Featured Speaker: Bert Vogelstein (Johns Hopkins School of Medicine; Howard Hughes Medical Institute)

    This eBriefing features the work of Bert Vogelstein, recipient of the 2015 Dr. Paul Janssen Award for Biomedical Research, and covers topics at the forefront of precision medicine.

    Annals

    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents discussions ofnutrition and the science of disease prevention; designing optogenetically controlled RNA for regulating biological systems; and how ion channels sense mechanical force

    Volume 1352