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  • Biochemistry, Biophysics & Structural Biology

  • Events 

    Friday, May 24, 2013 | 8:30 AM - 4:30 PM

    Targeting Epigenetic Regulators for Cancer Therapy

    Speakers: Scott A. Armstrong (Memorial Sloan-Kettering Cancer Center), Stephen Baylin (The Johns Hopkins University School of Medicine), Robert A. Copeland (Epizyme, Inc.), Vicki L. Goodman (GlaxoSmithKline), Haitao Li (Tsinghua University, China), X. Shirley Liu (Dana-Farber Cancer Institute), Robert Sims (Constellation Pharmaceuticals, Inc.), Alexander Tarakhovsky (The Rockefeller University)

    Epigenetic research has shown that heritable changes in cancer cell transformation occur beyond the primary DNA sequence. This symposium reviews epigenetic regulators in cancer development and progress in designing therapies targeting the epigenome.

    Monday, June 3, 2013 | 1:00 PM - 4:00 PM

    Genome Integrity Discussion Group Meeting

    Organizers: John Petrini (Memorial Sloan-Kettering Cancer Center), Rodney Rothstein (Columbia University Medical Center), Lorraine Symington (Columbia University Medical Center)
    Keynote Speaker: Stephen West (London Research Institute, Cancer Research UK)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Wednesday, June 5, 2013 | 12:00 PM - 4:00 PM

    Chemical Biology Discussion Group Year-End Symposium

    Keynote Speaker: Alanna Schepartz (Yale University)
    Speakers: Han Guo (Luo lab, Memorial Sloan–Kettering Cancer Center), Rudy Jacquet (Montclare lab, NYU-Poly), Neel Shah (Muir lab, Princeton University), Monika Raj (Arora lab, NYU), Wenjiao Song (Jaffrey lab, Weill Medical College, Cornell University), and Carola Wilczek (Shechter lab, Albert Einstein College of Medicine)

    The Chemical Biology Discussion Group brings together chemists and biologists interested in discussing the latest breakthroughs. The year-end meeting features keynote speaker Alana Schepartz of Yale University and a poster session.

    Friday, October 4, 2013 | 8:30 AM - 4:30 PM

    The Microbiome in Health, Disease, and Therapeutics: Bugs, Guts and Drugs

    Speakers: David Artis (University of Pennsylvania), Stephen M. Collins (McMaster University), Michael A. Fischbach (University of California, San Francisco), Dirk Gevers (The Broad Institute of MIT and Harvard), Jeremy K. Nicholson (Imperial College London), Lita M. Proctor (National Human Genome Research Institute, NIH)

    Symbioses between humans and our gut microbiome influence human biology including nutrition, immune function, and brain development. We review how symbiotic relationships impact drug metabolism and development, and a variety of disease states. This symposium features a poster session.

  • Past Events

    Monday, May 6, 2013 | 8:15 AM - 4:00 PM

    Translating Natural Products into Drugs for Alzheimer's and Neurodegenerative Disease

    Speakers: Kurt R. Brunden (University of Pennsylvania), Grant J. Carr (AMRI), Gabriela Chiosis (Memorial Sloan-Kettering Cancer Center), Jerold Chun (The Scripps Research Institute), Bonnie M. Davis (Synaptec), Chad Dickey (University of South Florida), Frank E. Koehn (Pfizer Global R&D), David J. Newman (National Cancer Institute, NIH), Salvatore Oddo (University of Texas Health Science Center, San Antonio), Giulio Maria Pasinetti (Mount Sinai School of Medicine)

    Alzheimer's disease may benefit from the novel chemistries found in natural products. This conference explores drug discovery from natural products, including novel approaches and technologies, and promising Alzheimer's drug discovery programs.

    Monday, April 1, 2013 | 1:00 PM - 4:00 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Craig Bassing (University of Pennsylvania), Dirk Remus (Memorial Sloan-Kettering Cancer Center), Yossi Shiloh (Tel Aviv University), Mikel Zaratiegui (Rutgers, the State University of New Jersey)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Wednesday, March 20, 2013 | 12:00 PM - 4:00 PM

    Autism Spectrum Disorder: From Genes to Circuits to Behavior

    Speakers: Ben Philpot (University of North Carolina, Chapel Hill), Tim Roberts (The Children's Hospital of Philadelphia), Stephan Sanders (Yale University School of Medicine), Laurence Tecott (University of California, San Francisco), Paul Wang (Seaside Therapeutics)

    Explore recent breakthroughs in early detection of autism and promising therapeutic interventions. This symposium features presents updates on the genetic landscape, the use of mouse models to explore behavior and potential therapeutic biomarkers.

    Tuesday, March 12, 2013 | 8:30 AM - 4:30 PM

    The Good Fat: Understanding Adipogenesis and Function of Brown Fat

    Speakers: Sheng Bi (Johns Hopkins University School of Medicine), Sheila Collins (Sanford-Burnham Medical Research Institute, Diabetes and Obesity Research Center), Abdul G. Dulloo (University of Fribourg), Vicente Gilsanz (Children's Hospital Los Angeles), Andrew C. Larner (Virginia Commonwealth University), David A. Price, Pfizer, Inc, Devanjan Sikder (Sanford-Burnham Medical Research Institute, Diabetes and Obesity Research Center), J. Enrique Silva (Tufts University School of Medicine), Bruce M Spiegelman (Dana-Farber Cancer Institute, Harvard Medical School), Anne-Ulrike Trendelenburg (Novartis Institutes for BioMedical Research, Yu-Hua Tseng (Joslin Diabetes Center, Harvard Medical School), Richard L. Veech (National Institute on Alcohol Abuse and Alcoholism/NIH)

    This conference will present recent research exploring adipogenesis focusing on brown adipose tissue, and will explore its implications in diet-induced obesity.

  • Publications 

    eBriefing

    Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments

    Organizer: Steven Gross (Weill Cornell Medical College)
    Keynote Speaker: Lewis C. Cantley (Weill Cornell Medical College)
    Speakers: Shuibing Chen (Weill Cornell Medical College), Ubaldo Martinez-Outschoorn (Thomas Jefferson University), and Andre Terzic (Center for Regenerative Medicine, Mayo Clinic)

    Does stem cell fate dictate metabolic activity or do metabolic switches trigger a commitment to cell fate? This eBriefing presents the latest research on stem cell metabolism, lineage commitment, and future therapies.

    Annals

    Annals Meeting Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents the following three meeting reports (1) Biomarkers in nutrition: new frontiers in research and application; (2) The new revolution in toxicology: The good, the bad, and the ugly; and (3) Neuroprotection after cerebral ischemia.

    Volume 1278

    Free online access provide by the Sackler Institute for Nutrition Science

    eBriefing

    The 8th Gotham-Metro Condensed Matter Meeting: Tapping NYC's Science and Engineering Talent

    Keynote Speakers: KC Huang (Stanford University) and Amir Yacoby (Harvard University)
    Panel Moderator: Seth Pinsky (NYC Economic Development Corporation)

    This eBriefing documents the 8th condensed matter physics conference featuring keynote talks in hard matter and soft matter as well as a special panel discussion, "Generation Tech: Tapping NYC's Science & Engineering Talent," featuring representatives of the new engineering and applied science institutions that are being created in the city.

    eBriefing

    The Paradox of Overnutrition in Aging and Cognition

    Organizers: Deborah R. Gustafson (SUNY Downstate Medical Center; University of Gothenburg, Sweden), John G. Kral (SUNY Downstate Medical Center), and Mandana Arabi (The Sackler Institute for Nutrition Science)

    Alzheimer's disease is expected to triple in the U.S. by 2050 and obesity is already epidemic. This eBriefing presents research on the link between overnutrition and cognition which suggests that obesity may play a role in and age-related diseases.

  • Podcasts

    Podcast
    January 1, 2010

    The Science of Sushi

    Danish biophysicist Ole Mouritsen also happens to be an expert on, and lover of sushi. This week, we talk to him about his new book, Sushi: Food for the Eye, the Body, and the Soul.

    Download (9 MB, 00:14:52)
    Podcast
    December 18, 2009

    No Small Matter

    We sit down with science photographer Felice Frankel and nanotechnology pioneer and Harvard chemist George Whitesides to hear about their new book on nanoscience, No Small Matter.

    Download (11 MB, 00:18:04)
  • Webinar Archives

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.