Comments*

 
  • Biochemistry, Biophysics & Structural Biology

  • Events 

    Friday, September 18, 2015 | 8:30 AM - 4:30 PM

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Speakers: George S. Bloom (University of Virginia), Peter Davies (The Feinstein Institute for Medical Research), Marc I. Diamond (University of Texas, Southwestern Medical Center), Michael Hutton (Eli Lilly and Company), Khalid Iqbal (New York State Institute for Basic Research in Developmental Disabilities), Hartmuth C. Kolb (Johnson & Johnson, Janssen R&D), Nicole Leclerc (Université de Montréal), Richard Ransohoff (Biogen)

    Speakers at this symposium will address novel tau-centered mechanisms of neurodegeneration and new therapeutic approaches for many devastating neurological disorders.

    Tuesday, September 29, 2015 | 12:00 PM - 5:00 PM

    Visualizing Cellular Messengers

    Speakers: Samie R. Jaffrey (Weill Cornell Medical College), Amy E. Palmer (University of Colorado)

    This symposium features state of the art chemical tools and imaging strategies for metal ions, redox signaling species, and metabolites in the cell, cellular delivery and targeting approaches, and their application to studying life processes.

    Tuesday, October 27, 2015 | 8:30 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras Bauer (Boehringer Ingelheim), Alex Huang (Genentech), Bryan Laffitte (Genomics Institute of the Novartis Research Foundation), Jonathan Lee (Eli Lilly ), Lorenz Mayr (AstraZeneca), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Robert Temple (US Food and Drug Administration )

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

  • Past Events

    Monday, June 1, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Keynote Speaker: Anne Villeneuve (Stanford University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Monday, May 18, 2015 | 11:30 AM - 5:00 PM

    Chemical Biology Discussion Group Year-End Symposium

    Keynote Speaker: Scott J. Miller (Yale University)

    The Chemical Biology Discussion Group brings together chemists and biologists interested in discussing the latest breakthroughs. The year-end meeting features keynote speaker Scott J. Miller of Yale University and a poster session.

    Monday, April 6, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Jef Boeke (NYU Langone Medical Center), Mike Glickman (Memorial Sloan-Kettering Cancer Center), Eric Greene (Columbia University Medical Center), Evgeny Nudler (NYU Langone Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, March 24, 2015 | 11:45 AM - 4:00 PM

    Positive Allosteric Modulators for Challenging GPCRs: Identification and Optimization

    Speakers: P. Jeffrey Conn (Vanderbilt University), Ron Dror (Stanford University), Christopher Fotsch (Amgen), Corey Hopkins (Vanderbilt University), Whitney Nolte (Pfizer)

    In this symposium, academic and industry scientists will describe the identification, characterization, and development of PAMs for challenging GPCRs.

  • Publications 

    eBriefing

    Click Chemistry in Biology and Medicine

    Organizers: Peng Wu (Albert Einstein College of Medicine) and Jennifer Henry (formerly at The New York Academy of Sciences)
    Keynote Speakers: Jim Paulson (Scripps Research Institute) and K. Barry Sharpless (Scripps Research Institute)

    This eBriefing explores recent developments in the search for click reactions with applications in disease diagnosis and therapy.

    eBriefing

    Elucidating GPCR Functional Selectivity for Drug Development

    Organizers: John A. Allen (Pfizer), Mercedes Beyna (Pfizer), Bryan L. Roth (University of North Carolina School of Medicine), and Jennifer Henry (formerly at The New York Academy of Sciences)

    This eBriefing looks at how to exploit biased ligand signaling at GPCRs to improve therapeutics for cardiovascular and CNS disorders.

    eBriefing

    From Bacterial Immunity to Genome Editing: The 2014 Dr. Paul Janssen Award Symposium

    Featured Speakers: Emmanuelle Charpentier (Helmholtz Centre for Infection Research, Hannover Medical School, Germany; Umeå University, Sweden) and Jennifer Doudna (University of California, Berkeley; Howard Hughes Medical Institute)

    This eBriefing features Emmanuelle Charpentier and Jennifer Doudna, recipients of the 2014 Dr. Paul Janssen Award for Biomedical Research for their role in understanding and adapting the CRISPR/Cas system for genome editing.

    eBriefing

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation), Kevin J. Lee (Lawrence Ellison Foundation), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing explores advances in the science of aging and in drug discovery for Alzheimer's and other neurodegenerative diseases.

  • Podcasts

    A recent conference held at the Academy asked a downright outrageous question: Can dementia be prevented by making changes to your diet? In this podcast we look at what the answers might be.

    Download (87 MB, 38:11)

    In the second of a two-part series, experts look at the links between health and nutrition. They examine everything from how nutrition impacts hospital stays, to cancer and aging, to developing food science innovations, and improving diet.

    Download (45 MB, 19:56)

    In this first of a two-part series, experts from various sectors explore the available options to reduce "hidden hunger"—micronutrient deficiencies in a population.

    Download (71 MB, 31:13)
  • Webinar Archives

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.