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  • Biochemistry, Biophysics & Structural Biology

  • Events 

    Friday, May 9, 2014 | 8:00 AM - 4:00 PM

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Speakers: Carmela R. Abraham (Boston University School of Medicine), Eric H. Baehrecke (University of Massachusetts Medical School), Nir Barzilai (Albert Einstein College of Medicine), Jerry R. Colca (Metabolic Solutions Development Company), Brendan D. Manning (Harvard School of Public Health), Beth Stevens (Harvard Medical School), D. Martin Watterson (Northwestern University Feinberg School of Medicine), Haung Yu (Columbia University), Jeffrey W. Kelly (The Scripps Research Institute), Richard I. Morimoto (Northwestern University)

    Age is the major risk factor for Alzheimer's disease, and key pathways in aging biology offer targets for novel drugs. Explore recent advances in the science of aging and innovative drug discovery for Alzheimer's and other neurodegenerative diseases.

    Monday, June 2, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Keynote Speaker: Julie Cooper (National Cancer Institute, NIH)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, June 3, 2014 | 9:30 AM - 2:30 PM

    Chemical Biology Discussion Group Year-End Symposium

    Keynote Speaker: Michael Marletta (The Scripps Research Institute)

    The Chemical Biology Discussion Group brings together chemists and biologists interested in discussing the latest breakthroughs. The year-end meeting features keynote speaker Michael Marletta of the Scripps Research Institute and a poster session.

    Thursday, July 31, 2014 | 8:00 AM - 5:00 PM

    Fifty Years of the Genetic Code:
    A Symposium to Honor the Legacy of Marshall Nirenberg

    Speakers: C. Thomas Caskey (Baylor College of Medicine, Houston, TX, USA), Jason Chin (University of Cambridge, UK), Gregory A. Petsko (Weill Cornell Medical College, New York, NY, USA), Frank Portugal (The Catholic University of America, Washington, DC, USA), Venki Ramakrishnan (MRC Laboratory of Molecular Biology, Cambridge, UK), Jonathan Weissman (University of California - San Francisco, California, CA, USA), Lei Wang (The Salk Institute for Biological Studies, La Jolla, California, USA), Huanming Yang (BGI, Shenzhen, China)

    The identification of the genetic code has offered many opportunities in scientific, medical and biological discovery. This symposium honors Nobel Laureate Marshall Nirenberg and showcases research in a range of therapeutic areas.

    Tuesday, September 30, 2014 | 8:00 AM - 5:00 PM

    Elucidating GPCR Functional Selectivity: Novel Opportunities for Drug Development

    Keynote Speaker: Nobel Laureate Robert J. Lefkowitz (Duke University Medical Center)
    Speakers: Bryan Roth (University of North Carolina at Chapel Hill School of Medicine), Terry Kenakin (University of North Carolina at Chapel Hill School of Medicine), Marc G. Caron (Duke University Medical Center), Laura Bohn (The Scripps Research Institute), Michael Ehlers (Pfizer), JoAnn Trejo (University of California-San Diego), Jonathan Violin (Trevena, Inc.)

    Hear academic, industry, basic and translational researchers, including Nobel Laureate Robert Lefkowitz (Duke University Medical Center) and discuss the development of functionally selective GPCR-biased ligands for CV and CNS disease drug discovery.

  • Past Events

    Thursday, April 10, 2014 | 8:30 AM - 4:30 PM

    Mitochondria, Metabolism and Disease

    Speakers: Robert Balaban (National Heart, Lung, and Blood Institute, NIH), Robert Bao (Massachusetts General Hospital), Salvatore DiMauro (Columbia University Medical Center), Steven Gross (Weill Cornell Medical College), Costas A. Lyssiotis (Weill Cornell Medical College), Jared Rutter (University of Utah School of Medicine), Hazel H. Szeto (Weill Cornell Medical College), Benjamin P. Tu (UT Southwestern Medical Center)

    Damage to mitochondria, which are critical in metabolism, underlies a wide range of human diseases, making them an important therapeutic target. Researchers aim to characterize and cure diseases arising from aberrant mitochondrial metabolism.

    Monday, April 7, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Leemor Joshua-Tor (Cold Spring Harbor Laboratory), John Pascal (Thomas Jefferson University), Orlando Scharer (Stony Brook University), Shan Zha (Columbia University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Monday, February 3, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Uttiya Basu (Columbia University), Eric J. Brown (University of Pennsylvania), Samuel F. Bunting (Rutgers University), Robert P. Fisher (Icahn School of Medicine at Mount Sinai), Sarah J. Radford (McKim Lab, Waksman Institute, Rutgers University), Veronica Rodriguez-Bravo (Jallepalli Lab, Memorial Sloan-Kettering Cancer Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Thursday, January 23, 2014 | 9:00 AM - 5:30 PM

    New York Structural Biology Discussion Group 9th Winter Meeting

    Speakers: Jean Baum (Rutgers University), Stephen K. Burley (Center for Integrative Proteomics Research Rutgers, The State University of New Jersey), Jiamu Du (Memorial Sloan-Kettering Cancer Center [Patel Lab]), Marta Filizola (Icahn School of Medicine at Mount Sinai), Stevan Hubbard (NYU), Reza Khayat (City College of New York), Sebastian Klinge (The Rockefeller University), Alexei Korennykh (Princeton University ), John P. Moore (Weill Medical College of Cornell University), Frances-Camille Padlan (Albert Einstein College of Medicine), Arthur G. Palmer III (Columbia University ), Dirk Remus (Memorial Sloan Kettering Cancer Center)

    The New York Area Structural Biology Discussion Group convenes twice annually and presents talks and poster sessions from graduate students, postdocs, and laboratory heads.

  • Publications 

    eBriefing

    Nanomedicines: Addressing the Scientific and Regulatory Gap

    Organizers: Raj Bawa (Bawa Biotech LLC; Rensselaer Polytechnic Institute), Scott E. McNeil (Nanotechnology Characterization Laboratory – Frederick National Laboratory for Cancer Research), Stefan Mühlebach (Vifor Pharma Ltd.; University of Basel, Switzerland), Melanie Brickman Stynes (The New York Academy of Sciences), and Melinda Miller (The New York Academy of Sciences)
    Keynote Speaker: Sally Tinkle (Science and Technology Policy Institute, IDA)

    This eBriefing explores regulatory challenges in the nascent field of nanomedicines.

    eBriefing

    The Microbiome in Health, Disease, and Therapeutics: Bugs, Guts, and Drugs

    Organizers: Mercedes Beyna (Pfizer), Robert Martone (Covance Biomarker Center of Excellence), Nilufer Seth (Pfizer), Richard Snyder (Covance Biomarker Center of Excellence), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing looks at how symbioses between humans and the gut microbiome impact drug metabolism, development, and a variety of disease states.

    eBriefing

    Understanding Somatosensation and Pain: The 2013 Dr. Paul Janssen Award Symposium

    Featured Speaker: David Julius (University of California, San Francisco)

    This eBriefing features David Julius, the recipient of the 2013 Dr. Paul Janssen Award for Biomedical Research for his role in discovering a mechanism for nociception and thermosensation. Recent research on pain is also described.

    eBriefing

    Translating Natural Products into Drugs for Alzheimer's and Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation) and Jennifer Henry (The New York Academy of Sciences)

    Alzheimer's disease may benefit from the novel chemistries found in natural products. The eBriefing explores drug discovery from natural products for Alzheimer's and other neurodegenerative diseases.

  • Podcasts

    Podcast
    January 1, 2010

    The Science of Sushi

    Danish biophysicist Ole Mouritsen also happens to be an expert on, and lover of sushi. This week, we talk to him about his new book, Sushi: Food for the Eye, the Body, and the Soul.

    Download (9 MB, 00:14:52)
    Podcast
    December 18, 2009

    No Small Matter

    We sit down with science photographer Felice Frankel and nanotechnology pioneer and Harvard chemist George Whitesides to hear about their new book on nanoscience, No Small Matter.

    Download (11 MB, 00:18:04)
  • Webinar Archives

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.