• Computational Biology

  • Events 

    Tuesday, October 27, 2015 | 8:00 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras J. Bauer (Boehringer Ingelheim USA), Michael R. Jackson (Sanford Burnham Prebys Medical Discovery Institute), Jonathan A. Lee (Eli Lilly), Martin Main (AstraZeneca), Friedrich Metzger (F. Hoffmann-La Roche Ltd), Bruce A. Posner (University of Texas, Southwestern Medical Center), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Susanne Swalley (Novartis Institutes for Biomedical Research)

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

    Tuesday, March 22, 2016 | 12:00 PM - 4:00 PM

    Neuronal Connectivity in Brain Function and Disease: Novel Mechanisms and Therapeutic Targets

    Speakers: Wenbiao Gan (NYU Langone Medical Center), Bruce McEwen (Rockefeller University), Eric Nestler (Mount Sinai School of Medicine), Amy Robinson (MIT), Bernardo Sabatini (Harvard Medical School), David Sulzer (Columbia University Medical Center)

    Mapping neuronal circuitry provides important insight into mammalian health and disease. This symposium will discuss emerging tools and novel findings that address this important goal.

  • Past Events

    September 30 - October 1, 2015

    Mobile Health: The Power of Wearables, Sensors, and Apps to Transform Clinical Trials

    Keynote Speaker: Ian Ferguson (ARM), Christian Stammel (Wearable Technologies AG)
    Speakers: Pam Baker (FierceBigData), Stan Berkow (Sense Health), Brian Bot (Sage Bionetworks), Michelle De Mooy (Consumer Privacy Project at Center for Democracy and Technology), Glen de Vries (Medidata), John Hixson (University of California at San Francisco), Julian Jenkins (GlaxoSmithKline), David C. Magnus (Stanford Center for Biomedical Ethics), Linda A. Malek (Moses and Singer, LLP), John Mastrototaro (Medtronic), Veena Misra (The NSF Nanosystems Engineering Research Center (NERC) for Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST) and North Carolina State University), Bernard Munos (FasterCures [a center of the Milken Institute]), Fiorenzo Omenetto (Tufts University), Aydogan Ozcan (UCLA and the Howard Hughes Medical Institute), Tomasz Sablinski (Transparency Life Sciences), Leonard Sacks (U.S. Food and Drug Administration), Pei Wang (Icahn School of Medicine at Mount Sinai)

    Continuous health monitoring using wearable sensors, mobile devices, and apps is becoming a powerful tool for assessing critical physiological parameters. The vast accumulation of real-time biometric data obtained from these technologies may hold invaluable clues for treating some of the most devastating human diseases.

    Friday, June 19, 2015 | 8:00 AM - 5:30 PM

    Microbes in the City:
    Mapping the Urban Genome

    Speakers: Joel Ackelsberg (NYC Department of Health and Mental Hygiene), Eric Alm (Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology), Martin J. Blaser (New York University Langone Medical Center), Ilana Brito (Massachusetts Institute of Technology), Jane Carlton (New York University Center for Genomics and Systems Biology), Rumi Chunara (New York University Polytechnic School of Engineering), Laurie Garrett (Council on Foreign Relations), Jack Gilbert (Argonne National Laboratory), Jo Handelsman (White House Office of Science and Technology Policy), Curtis Huttenhower (Harvard T.H. Chan School of Public Health), W. Ian Lipkin (Center for Infection and Immunity, Columbia University), Juan Maestre (The University of Texas at Austin), Christopher Mason (Institute for Computational Biomedicine, Weill Cornell Medical College), Paula Olsiewski (Alfred P. Sloan Foundation), Rachel Poretsky (University of Illinois at Chicago), Coby Schal (North Carolina State University Department of Entomology)

    Efforts to map all of the genetic information of microbial communities that make up the urban genome—from kiosks and subways, to soil and sewage—seek to improve the health and productivity of the built environments in which we live.

    Thursday, June 18, 2015 | 8:00 AM - 5:30 PM

    Quantitative Biology:
    From Molecules to Man

    Keynote Speaker: Steve Kay (University of Southern California)
    Speakers: Francis J. Doyle III (University of California Santa Barbara), Andrew Ewald, PhD (Johns Hopkins University), Scott E. Fraser (University of Southern California), Peter Kuhn (University of Southern California), Christopher E. Mason (Weill Cornell Medical College), Paul Newton (University of Southern California), Amanda Randles (Harvard University), Chris Sander (Memorial Sloan Kettering Cancer Center)

    Quantitative Biology: From Molecules to Man will bring together professionals in science, medicine, and engineering to articulate a vision for the future of improving patient health outcomes.

    Tuesday, May 26, 2015 | 8:30 AM - 4:30 PM

    Quantitative Systems Pharmacology: Progress Towards Integration into Drug Discovery and Development

    Speakers: Richard Allen (Pfizer, Inc.), John Burke (Applied BioMath), Nitin Mehrotra (US Food and Drug Administration), Sian Ratcliffe (Pfizer Inc), Matthew Rizk (Merck & Co, Inc), Tim Rolph (Pfizer, Inc.), Vikram Sinha (US Food and Drug Administration), Peter Sorger (Harvard Medical School), Paul Watkins (Hamner-UNC Institute for Drug Safety Sciences)

    Quantitative Systems Pharmacology (QSP) has been used successfully in drug discovery and development, yet lacks industry-wide adoption. This symposium highlights past successes and future challenges of using QSP in preclinical and clinical research.

  • Publications 


    Nutrition and Disease Prevention: A Systems Approach to Metabolic Health

    Keynote Speaker: Frank Hu (Harvard T.H. Chan School of Public Health)

    This eBriefing explores research on metabolic health from several disciplines and looks at how different types of data combine to explain physiology and disease.


    Competitive Visual Processing Across Space and Time: Attention, Memory, and Prediction

    Edited by Werner X. Schneider (Bielefeld University), Wolfgang Einhäuser (Bielefeld University and Philipps-University Marburg), and Gernot Horstmann (Bielefeld University)

    This Annals volume explores three memory-related aspects of competitive visual processing: interactions of attention and working memory, attention and long-term memory, and attention and prediction.

    Volume 1339


    Systems Biology Approaches to Secondary Metabolites and Metabonomics

    Organizers: Manuel X. Duval (Boehringer Ingelheim Pharmaceuticals; University of New Haven), Thomas B. Freeman (Boehringer Ingelheim Pharmaceuticals), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Sean F. Brady (The Rockefeller University), Steven Edgar (Massachusetts Institute of Technology), Justin Nodwell (University of Toronto, Canada), and Kang Zhou (Massachusetts Institute of Technology)

    This eBriefing explores a systems biology approach to secondary metabolites and their networks, looking at their biological effects and potential benefits for human health.


    Venomics: Drug Discovery from Nature's Deadliest

    Organizers: Mandë Holford (Hunter College, CUNY; American Museum of Natural History), Steven Gross (Weill Cornell Medical College), and Jennifer Henry (The New York Academy of Sciences)
    Keynote Speaker: Baldomero M. Olivera (University of Utah)

    Venomous animals, including spiders, snakes, scorpions, sea snails, leeches, and others, produce millions of bioactive compounds, offering enormous potential for venom-based drug discovery.

  • Podcasts

    Understanding nutrition's impact on health requires an intricate knowledge of all the different systems within the human body. Learn how a systems approach to nutrition could change the field.

    Download (44 MB, 32:02)

    A recent conference held at the Academy asked a downright outrageous question: Can dementia be prevented by making changes to your diet? In this podcast we look at what the answers might be.

    Download (87 MB, 38:11)

    In the second of a two-part series, experts look at the links between health and nutrition. They examine everything from how nutrition impacts hospital stays, to cancer and aging, to developing food science innovations, and improving diet.

    Download (45 MB, 19:56)