• Computational Biology

  • Events 

    Tuesday, October 27, 2015 | 8:30 AM - 5:00 PM

    Phenotypic and Biomarker-Based Drug Discovery

    Speakers: Andras Bauer (Boehringer Ingelheim), Alex Huang (Genentech), Bryan Laffitte (Genomics Institute of the Novartis Research Foundation), Jonathan Lee (Eli Lilly ), Lorenz Mayr (AstraZeneca), Aravind Subramanian (Broad Institute), Giulio Superti-Furga (Austrian Academy of Sciences), Robert Temple (US Food and Drug Administration )

    This symposium aims to deepen our understanding of phenotypic drug discovery and to foster the exchange of ideas between industry-based and academic research scientists.

  • Past Events

    Friday, June 19, 2015 | 8:00 AM - 5:30 PM

    Microbes in the City:
    Mapping the Urban Genome

    Speakers: Joel Ackelsberg (NYC Department of Health and Mental Hygiene), Eric Alm (Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology), Martin J. Blaser (New York University Langone Medical Center), Ilana Brito (Massachusetts Institute of Technology), Jane Carlton (New York University Center for Genomics and Systems Biology), Rumi Chunara (New York University Polytechnic School of Engineering), Laurie Garrett (Council on Foreign Relations), Jack Gilbert (Argonne National Laboratory), Jo Handelsman (White House Office of Science and Technology Policy), Curtis Huttenhower (Harvard T.H. Chan School of Public Health), W. Ian Lipkin (Center for Infection and Immunity, Columbia University), Juan Maestre (The University of Texas at Austin), Christopher Mason (Institute for Computational Biomedicine, Weill Cornell Medical College), Paula Olsiewski (Alfred P. Sloan Foundation), Rachel Poretsky (University of Illinois at Chicago), Coby Schal (North Carolina State University Department of Entomology)

    Efforts to map all of the genetic information of microbial communities that make up the urban genome—from kiosks and subways, to soil and sewage—seek to improve the health and productivity of the built environments in which we live.

    Thursday, June 18, 2015 | 8:00 AM - 5:30 PM

    Quantitative Biology:
    From Molecules to Man

    Keynote Speaker: Steve Kay (University of Southern California)
    Speakers: Francis J. Doyle III (University of California Santa Barbara), Andrew Ewald, PhD (Johns Hopkins University), Scott E. Fraser (University of Southern California), Peter Kuhn (University of Southern California), Christopher E. Mason (Weill Cornell Medical College), Paul Newton (University of Southern California), Amanda Randles (Harvard University), Chris Sander (Memorial Sloan Kettering Cancer Center)

    Quantitative Biology: From Molecules to Man will bring together professionals in science, medicine, and engineering to articulate a vision for the future of improving patient health outcomes.

    Tuesday, May 26, 2015 | 8:30 AM - 4:30 PM

    Quantitative Systems Pharmacology: Progress Towards Integration into Drug Discovery and Development

    Speakers: Richard Allen (Pfizer, Inc.), John Burke (Applied BioMath), Nitin Mehrotra (US Food and Drug Administration), Sian Ratcliffe (Pfizer Inc), Matthew Rizk (Merck & Co, Inc), Tim Rolph (Pfizer, Inc.), Vikram Sinha (US Food and Drug Administration), Peter Sorger (Harvard Medical School), Paul Watkins (Hamner-UNC Institute for Drug Safety Sciences)

    Quantitative Systems Pharmacology (QSP) has been used successfully in drug discovery and development, yet lacks industry-wide adoption. This symposium highlights past successes and future challenges of using QSP in preclinical and clinical research.

    Thursday, April 16, 2015 | 8:00 AM - 5:00 PM

    Nutrition and the Science of Disease Prevention: A Systems Approach to Support Metabolic Health

    Keynote Speaker: Frank Hu (Harvard School of Public Health)
    Speakers: Brian Bennett (University of North Carolina), Kevin Hall (National Institutes of Health), Rudolph Leibel (Columbia University), Patricia Mabry (National Institutes of Health), Anne McCartney (University of Reading), Christina A. Roberto (Harvard T.H. Chan School of Public Health)

    This one-day conference will highlight the connection between nutrition and the complex science of preventing disease. Speakers will focus on promotion of optimal metabolic health, building on input from several complementary disciplines.

  • Publications 


    Competitive Visual Processing Across Space and Time: Attention, Memory, and Prediction

    Edited by Werner X. Schneider (Bielefeld University), Wolfgang Einhäuser (Bielefeld University and Philipps-University Marburg), and Gernot Horstmann (Bielefeld University)

    This Annals volume explores three memory-related aspects of competitive visual processing: interactions of attention and working memory, attention and long-term memory, and attention and prediction.

    Volume 1339


    Systems Biology Approaches to Secondary Metabolites and Metabonomics

    Organizers: Manuel X. Duval (Boehringer Ingelheim Pharmaceuticals; University of New Haven), Thomas B. Freeman (Boehringer Ingelheim Pharmaceuticals), and Jennifer Henry (The New York Academy of Sciences)
    Speakers: Sean F. Brady (The Rockefeller University), Steven Edgar (Massachusetts Institute of Technology), Justin Nodwell (University of Toronto, Canada), and Kang Zhou (Massachusetts Institute of Technology)

    This eBriefing explores a systems biology approach to secondary metabolites and their networks, looking at their biological effects and potential benefits for human health.


    Venomics: Drug Discovery from Nature's Deadliest

    Organizers: Mandë Holford (Hunter College, CUNY; American Museum of Natural History), Steven Gross (Weill Cornell Medical College), and Jennifer Henry (The New York Academy of Sciences)
    Keynote Speaker: Baldomero M. Olivera (University of Utah)

    Venomous animals, including spiders, snakes, scorpions, sea snails, leeches, and others, produce millions of bioactive compounds, offering enormous potential for venom-based drug discovery.


    Preclinical Drug–Drug Interaction: Risk Assessment and Toxicity

    Organizers: Myrtle Davis (National Cancer Institute, NIH), Raymond A. Kemper (Merck), Marla Weetall (PTC Therapeutics), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing explores approaches to predict potential drug–drug interactions before clinical trials in humans.

  • Podcasts

    A recent conference held at the Academy asked a downright outrageous question: Can dementia be prevented by making changes to your diet? In this podcast we look at what the answers might be.

    Download (87 MB, 38:11)

    In the second of a two-part series, experts look at the links between health and nutrition. They examine everything from how nutrition impacts hospital stays, to cancer and aging, to developing food science innovations, and improving diet.

    Download (45 MB, 19:56)

    In this first of a two-part series, experts from various sectors explore the available options to reduce "hidden hunger"—micronutrient deficiencies in a population.

    Download (71 MB, 31:13)