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  • Cell & Molecular Biology

  • Events 

    Monday, February 22, 2016 | 9:00 AM - 5:00 PM

    Regenerative Medicine: Transitioning Therapeutics from Cells to the Clinic

    Speakers: John F. DiPersio (Washington University School of Medicine), Jonathan D. Glass (Emory University School of Medicine), Edward O. Lanphier (Sangamo BioSciences, Inc.), Jane S. Lebkowski (Asterias Biotherapeutics), Racheli Ofir (Pluristem LTD), Mahendra Rao (Wake Forest University School of Medicine), Thomas Schulz (ViaCyte, Inc.), John D. Sinden (ReNeuron Limited), Katherine Tsokas (Janssen Research & Development)

    Advances in gene editing have driven an explosion of pre-clinical cell-based therapies. This event addresses the need to rethink clinical, regulatory, & manufacturing approaches to accelerate the transition of drugs through the clinic.

    Monday, February 29, 2016 | 9:00 AM - 5:00 PM

    Emerging Approaches to Cancer Immunotherapy

    Keynote Speakers: Renier Brentjens (Memorial Sloan Kettering Cancer Center), Jedd Wolchok (Memorial Sloan Kettering Cancer Center)
    Speakers: Jane Gross (Emergent Biosolutions, Inc), John Hunter (Compugen Ltd), Jane S. Lebkowski (Asterias Biotherapeutics), Jens-Peter Marschner (Affimed AG), Charles Nicolette (Argos Therapeutics, Inc), Charles L. Sentman (Dartmouth Geisel School of Medicine), David M Spencer (Bellicum Pharmaceuticals), Roland Walter (Fred Hutchinson Cancer Research Center)

    Emerging strategies for Cancer Immunotherapy are changing the face of cancer treatment. This symposium will bring together experts in immunotherapy and immunology to discuss emerging approaches, challenges, and opportunities in this evolving field

    Tuesday, March 15, 2016 | 8:30 AM - 4:30 PM

    Advances in Human Microbiome Science: Gut-Brain Interaction

    Speakers: Premysl Bercik (McMaster University Medical Centre), John F Cryan (University College Cork), Ted Dinan (University College Cork), Emeran Mayer (David Geffen School of Medicine, UCLA), Sarkis Mazmanian (California Institute of Technology), Vassilis Pachnis, MD (The Francis Crick Institute), Robert Yolken (John Hopkins School of Medicine)

    The gut microbiome is emerging as an important regulator of brain development, brain health, and disease. This symposium will highlight recent research innovations and therapeutic applications from the microbiome with a focus on CNS health.

    Tuesday, March 22, 2016 | 12:00 PM - 4:00 PM

    Neuronal Connectivity in Brain Function and Disease: Novel Mechanisms and Therapeutic Targets

    Speakers: Wenbiao Gan (NYU Langone Medical Center), Bruce McEwen (Rockefeller University), Eric Nestler (Icahn School of Medicine at Mount Sinai), Amy Robinson (MIT), Bernardo Sabatini (Harvard Medical School), David Sulzer (Columbia University Medical Center)

    Mapping neuronal circuitry provides important insight into mammalian health and disease. This symposium will discuss emerging tools and novel findings that address this important goal.

    March 30 - April 1, 2016

    Sohn Conference: Pediatric Cancer in a Post-genomic World

    Keynote Speakers: Richard Gilbertson (Cambridge Cancer Center, University of Cambridge), Craig B. Thompson (Memorial Sloan Kettering Cancer Center)
    Speakers: Scott Armstrong (Memorial Sloan Kettering Cancer Center), Eric Bouffet (The Hospital for Sick Children, Toronto), Stefan Burdach (Technical University of Munich, Germany), Michael Dyer (St. Jude Children's Research Hospital, Howard Hughes Medical Institute), Nancy Goodman (Kids V Cancer), Lee J. Helman (National Cancer Institute, National Institutes of Health), Nada Jabado (McGill University), Katherine A. Janeway (Dana-Farber Cancer Center, Harvard Medical School), Michael Jensen (Seattle Children's Hospital), Javed Khan (National Cancer Institute, National Institutes of Health), Andrew Kung (Columbia University Medical Center), A. Thomas Look (Dana-Farber Cancer Center, Harvard University), David C. Lyden (Weill Cornell Medical College), Elizabeth Maher (University of Texas Southwestern Medical Center), David Malkin (The Hospital for Sick Children), John Maris (The Children's Hospital of Philadelphia and the University of Pennsylvania), Yael Mossé (The Children’s Hospital of Philadelphia), Kathy Pritchard-Jones (Great Ormond Street Hospital for Children NHS Foundation Trust and University College London), Charles W.M. Roberts (St. Jude Children's Research Hospital), Michel Sadelain (Memorial Sloan Kettering Cancer Center), Paul M. Sondel (University of Wisconsin School of Medicine and Public Health), Poul H. Sorensen (University of British Columbia), Kimberly Stegmaier (Dana-Farber Cancer Institute), Michael D. Taylor (The Hospital for Sick Children, University of Toronto), Matthew Vander Heiden (The Koch Institute, Massachusetts Institute of Technology), Robert Wechsler-Reya (Sanford Burnham Prebys Institute of Medical Discovery)

    Discover the latest on pediatric cancers from leading experts, including etiological differences between pediatric and adult cancers, epigenetics, mechanisms of metastasis and disease recurrence, risk factors, diagnostics, and novel treatment approaches.

  • Past Events

    Monday, February 1, 2016 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group

    Speakers: Alberto Ciccia (Columbia University Medical Center), Maria Jasin (Memorial Sloan Kettering Cancer Center), Jun Hyun Kim (Memorial Sloan Kettering Cancer Center), Alexandra Pinzaru (NYU School of Medicine), Richard Pomerantz (Temple University), Patrick Sung (Yale University)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, December 8, 2015 | 8:30 AM - 4:45 PM

    GLP-1 Treatment for Diabetes and Beyond

    Speakers: David D'Alessio (Duke University), Richard DiMarchi (Indiana University), Jean-Philippe Fortin (Pfizer Global), Keld Fosgerau (Zealand Pharma A/S), Matthew R. Hayes (Perelman School of Medicine, University of Pennsylvania), George G. Holz (State University of New York), Beat Jucker (GlaxoSmithKline), Dong Seok Kim (National Institute on Aging / Peptron Inc), Lotte Bjerre Knudsen (Novo Nordisk), Patrick M. Sexton (Monash University), Konrad Talbot (Cedars-Sinai Medical Center)

    GLP-1 receptor agonists have improved treatment options in type 2 diabetes, although realizing their promise in other areas remains challenging. This symposium highlights preclinical and clinical breakthroughs and opportunities for drug development.

    Monday, December 7, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group

    Speakers: Jean Gautier (Columbia University Medical Center), Olga A. Guryanova (Weill Cornell Medical College), Jaspreet S. Khurana (Princeton University), Hannah Klein (NYU Langone Medical Center), Neal Lue (Weill-Cornell Medical College), Dirk Remus (Memorial Sloan Kettering Cancer Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Friday, December 4, 2015 | 8:30 AM - 6:00 PM

    Managing Disease-Related Lean Body Mass Loss through Clinical and Nutrition Interventions

    Speakers: Melissa J. Benton (University of Colorado at Colorado Springs), David Evans (The Ohio State University), Gordon Jensen (The Pennsylvania State University), Robert Martindale (Oregon Health & Science University Healthcare), Peter A. McCullough (Dallas Baylor Heart and Vascular Hospital), Gerard Mullin (Johns Hopkins Medicine), Dennis H. Sullivan (University of Arkansas), Paul Wischmeyer (University of Colorado School of Medicine)

    Lean Body Mass Loss Clinical and Nutrition Interventions

  • Publications 

    eBriefing

    Alzheimer's Disease and Tau: Pathogenic Mechanisms and Therapeutic Approaches

    Organizers: Robert Martone (St. Jude Children's Research Hospital) and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing explores tau-related mechanisms of neurodegeneration and emerging therapeutic strategies focused on tau.

    eBriefing

    Phenotypic and Biomarker-based Drug Discovery

    Organizers: Michael Foley (Tri-Institutional Therapeutics Discovery Institute), Ralph Garippa (Memorial Sloan-Kettering Cancer Center), David Mark (F. Hoffmann-La Roche), Lorenz Mayr (Astra Zeneca), John Moffat (Genentech), Marco Prunotto (F. Hoffmann-La Roche), and Sonya Dougal (The New York Academy of Sciences)

    This eBriefing considers the merits of phenotypic drug discovery, which is experiencing a renaissance of interest. The method aims to find therapeutically useful compounds by screening thousands of substances for functional cellular outputs.

    eBriefing

    Advances in Human Microbiome Science: Intestinal Diseases

    Organizers: Mercedes Beyna (Pfizer), John Hambor (Boehringer Ingelheim), Nilufer Seth (Pfizer), Erick Young (Boehringer Ingelheim), and Sonya Dougal (The New York Academy of Sciences)
    Keynote Speaker: Stanislav Dusko Ehrlich (French National Institute for Agricultural Research; King's College London)

    This eBriefing focuses on the causal relationships between gut microbiota and intestinal health and disease.

    Annals

    B-1 Cell Development and Function

    Edited by Thomas L. Rothstein (The Feinstein Institute for Medical Research), Leonore A. Herzenberg (Stanford University School of Medicine), Nichol E. Holodick (The Feinstein Institute for Medical Research), and Eliver Ghosn (Stanford University School of Medicine)

    These papers discuss the physiological role of a unique subpopulation of B lymphocytes called B-1 cells.