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  • Cell & Molecular Biology

  • Events 

    Monday, April 6, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Jef Boeke (NYU Langone Medical Center), Mike Glickman (Memorial Sloan-Kettering Cancer Center), Eric Greene (Columbia University Medical Center), Evgeny Nudler (NYU Langone Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Tuesday, April 7, 2015 | 8:30 AM - 5:00 PM

    Cytokine-Based Immunotherapies

    Keynote Speaker: James W. Mier (Beth Israel Deaconess Medical Center/ Harvard Medical School, Boston, MA)
    Speakers: Renier J. Brentjens (Memorial Sloan Kettering Cancer Center), Stephen D. Gillies (Provenance Biopharmaceuticals, Carlisle, MA), Jerome Ritz (Harvard Medical School), Gilles Uzé (Université Montpellier II, Montpellier, France), K. Dane Wittrup (Massachusetts Institute of Technology, Cambridge, MA)

    Systemic toxicity currently prevents exploiting the potential of many cytokines to treat cancer, viral infections, inflammatory and autoimmune conditions. Targeted delivery of immune-stimulatory or immune-regulatory cytokines offers much promise.

    Thursday, May 21, 2015 | 9:00 AM - 5:00 PM

    Emerging Approaches to Cancer Immunotherapy

    Speakers: Rolf Brekken (University of Texas, Southwestern), Stephen J. Forman (City of Hope), Thomas F. Gajewski (The University of Chicago Medicine), Carl June (University of Pennsylvania), David Kaufman (Merck Research Laboratories), Mark R. Litzow (Mayo Clinic), Andy Minn (University of Pennsylvania), Elaine Pinheiro (Merck Research Laboratories), Robert Vonderheide (University of Pennsylvania)

    This symposium will bring together leading experts in immunotherapy and immunology to discuss these emerging approaches, along with the challenges and opportunities faced in this evolving field.

    Tuesday, May 26, 2015 | 8:30 AM - 4:30 PM

    Quantitative Systems Pharmacology: Progress Towards Integration into Drug Discovery and Development

    Speakers: Richard Allen (Pfizer), John Burke (Applied BioMath), Nitin Mehrotra (US Food and Drug Administration), Tim Rolph (Pfizer), Vikram Sinha (US Food and Drug Administration), Peter Sorger (Harvard Medical School), Paul Watkins (Hamner-UNC Institute for Drug Safety Sciences)

    Quantitative Systems Pharmacology (QSP) has been used successfully in drug discovery and development, yet lacks industry-wide adoption. This symposium highlights past successes and future challenges of using QSP in preclinical and clinical research.

    Thursday, May 28, 2015 | 8:00 AM - 3:00 PM

    Cancer Cell Metabolism: Unique Features Inform New Therapeutic Opportunities

    Keynote Speaker: Craig Thompson (Memorial Sloan-Kettering Cancer Center)
    Speakers: John Blenis (Weill Cornell Medical College ), Lydia Finley (Memorial Sloan-Kettering Cancer Center), Alec Kimmelman (Harvard Medical School), Christian M. Metallo (University of California, San Diego ), Elena Piskounova (University of Texas, Southwestern ), Sohail Tavazoie (The Rockefeller University )

    This symposium will highlight insights into tumor metabolism from leaders in the field and explore how this information is being used to design safe and effective, metabolism-targeted therapies.

  • Past Events

    Tuesday, March 24, 2015 | 11:45 AM - 4:00 PM

    Positive Allosteric Modulators for Challenging GPCRs: Identification and Optimization

    Speakers: P. Jeffrey Conn (Vanderbilt University), Ron Dror (Stanford University), Christopher Fotsch (Amgen), Corey Hopkins (Vanderbilt University), Whitney Nolte (Pfizer)

    In this symposium, academic and industry scientists will describe the identification, characterization, and development of PAMs for challenging GPCRs.

    Tuesday, February 24, 2015 | 8:30 AM - 4:30 PM

    Harnessing the Potential of Genome Editing for Drug Discovery: Translational Frontiers of in vitro and in vivo Applications

    Speakers: Chad Cowan (Harvard University), James Inglese (National Center for Advancing Translational Sciences, NIH), J. Keith Joung (Massachusetts General Hospital), Randall Platt (Massachusetts Institute of Technology), Yi Yang (Novartis Institutes for Biomedical Research), Lei (Stanley) Qi (University of California San Francisco)

    The emergence of genome editing technologies such as TALEN and CRISPR/Cas9 are revolutionizing our ability to rapidly engineer mammalian systems. This symposium explores the frontiers of genome editing and potential to aid therapeutic development.

    Monday, February 2, 2015 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Prasad Jallepalli (Memorial Sloan-Kettering Cancer Center), Shelley Berger (University of Pennsylvania), Iestyn Whitehouse (Memorial Sloan-Kettering Cancer Center), John Petrini (Memorial Sloan-Kettering Cancer Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Wednesday, January 21, 2015 | 8:30 AM - 4:00 PM

    The New York Structural Biology Discussion Group 10th Winter Meeting

    Speakers: Jasna Brujic (New York University), Bridget Carragher, John Chodera, Oliver Clarke, Erik Debler, Nancy Greenbaum, David Hall, Barry Honig, Jinrang Kim (Columbia University), Nina Liu (Albert Einstein College of Medicine), Patrick Loria (Yale University), Sean McSweeney (Brookhaven National Lab), Clint Potter

    The New York Area Structural Biology Discussion Group convenes twice annually and presents talks and poster sessions from graduate students, postdocs, and laboratory heads.

  • Publications 

    Annals

    The Year in Neurology and Psychiatry

    Edited by Daniel H. Geschwind (University of California, Los Angeles)

    Scholarly reviews of topics in neurology and psychiatry--a new Annals series.

    eBriefing

    Diabetic Kidney Disease: Drug Discovery and Clinical Development Challenges

    Organizers: Magdalena Alonso-Galicia (MAG Pharma Consulting LLC), Ken Jones (Allergan), Scott MacDonnell (Boehringer Ingelheim Pharmaceuticals), and Jennifer Henry (formerly at The New York Academy of Sciences)

    This eBriefing reviews targets for preventive or therapeutic interventions in diabetic kidney disease and discusses clinical development.

    Annals

    MARROW

    Edited by Mone Zaidi (Mount Sinai School of Medicine, New York, New York)

    A new series in Annals, MARROW presents cutting-edge manuscripts on basic, translational, and clinical bone and bone marrow biology and medicine.

    Annals

    Annals Reports

    Edited by Annals of the New York Academy of Sciences editorial staff

    This Annals volume presents two meeting reports: (1) Influencing circadian and sleep–wake regulation for prevention and intervention in mood and anxiety disorders: what makes a good homeostat?; and (2) One Medicine One Science: a framework for exploring challenges at the intersection of animals, humans, and the environment.

    Volume 1334

  • Podcasts

    Podcast
    September 10, 2010

    What Makes Us Wise?

    Can we all be wise old owls? Science journalist Stephen Hall and neuroscientist Andre Fenton dissect what we call wisdom, from the neurons in our brain, to the social constructs behind it.

    Download (22 MB, 00:42:32)
    Podcast
    July 30, 2010

    Oxidative Stress

    Foods high in antioxidants are believed to fight oxidative stress. But what is oxidative stress? Two scientists from a recent NYAS conference break it down and discuss whether antioxidants have superpowers.

    Download (12 MB, 00:18:37)
    Podcast
    July 2, 2010

    What's that Smell?

    Biologist Stewart Firestein and world-renowned perfumer Christophe Laudamiel team up to tackle the science of smell.

    Download (32 MB, 00:49:12)
    Podcast
    April 2, 2010

    More than a Yogurt Cup

    Delve into the world of prebiotic and probiotic science. We talk to three people in the field and learn why keeping the good microbes in our bodies happy means a lot for health.

    Download (14 MB, 00:21:21)
  • Webinar Archives

    Webinar Archive
    February 23, 2010

    Metabotropic Glutamate Receptors: Translation from Discovery to Clinical Trials

    Researchers met to discuss advances in basic and translational research on metabotropic glutamate receptors, which are promising targets in drug discovery for CNS diseases and other illnesses.

    Webinar Archive
    October 27, 2009

    Is Alzheimer's Disease Type 3 Diabetes?

    What is the connection between dysregulated neuronal insulin signaling and Alzheimer's disease? In a recent Academy webinar, some researchers argued that the neurodegenerative disease should be considered a type of diabetes.

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.