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  • Cell & Molecular Biology

  • Events 

    Monday, September 15, 2014 | 12:00 PM - 4:00 PM

    Click Chemistry in Biology and Medicine: New Developments and Strategies

    Keynote Speakers: Jim Paulson (The Scripps Research Institute), K. Barry Sharpless (The Scripps Research Institute)
    Speakers: Yimon Aye (Cornell University), David A. Spiegel (Yale University), Peng Wu (Albert Einstein College of Medicine)

    Click chemistry offers a reliable method for discovering chemical connectivity, with great potential in drug discovery and biomedical research. This symposium explores recent developments that offer new technologies for disease diagnosis and therapy.

    Tuesday, September 30, 2014 | 8:30 AM - 5:00 PM

    Elucidating GPCR Functional Selectivity: Novel Opportunities for Drug Development

    Keynote Speaker: Nobel Laureate Robert J. Lefkowitz (Duke University Medical Center)
    Speakers: Bryan Roth (University of North Carolina at Chapel Hill School of Medicine), Terry Kenakin (University of North Carolina at Chapel Hill School of Medicine), Marc G. Caron (Duke University Medical Center), Laura Bohn (The Scripps Research Institute), Michael Ehlers (Pfizer), JoAnn Trejo (University of California-San Diego), Jonathan Violin (Trevena, Inc.)

    Hear academic, industry, basic and translational researchers, including Nobel Laureate Robert Lefkowitz (Duke University Medical Center) and discuss the development of functionally selective GPCR-biased ligands for CV and CNS disease drug discovery.

    Tuesday, October 28, 2014 | 8:30 AM - 5:00 PM

    Pharmacologic Resolution of Inflammation as a Novel Therapeutic Approach

    Speaker: Michael S. Conte (University of California-San Francisco, San Francisco, CA), Milan Fiala (David Geffen School of Medicine at UCLA, Los Angeles, CA), Gabrielle Fredman (Columbia University, New York, NY), Bruce Levy (Harvard University, Brigham and Women's Hospital, Boston, MA), Dipak Panigrahy (Beth Israel Deaconess Medical Center, Boston, MA), Mauro Perretti (William Harvey Research Institute, London, UK), Charles N. Serhan (Harvard University, New York, NY), Patricia J. Sime (University of Rochester School of Medicine, Rochester, NY), Rudy Tanzi (Massachusetts General Hospital, Charlestown, MA)

    Uncontrolled, chronic inflammation plays a key role in the progression of many diseases, and elucidation of biochemical pathways provides novel targets. This symposium reviews discoveries, approaches and opportunities for treatment and prevention.

    Monday, November 3, 2014 | 8:00 AM - 4:30 PM

    Gene Network Changes in Alzheimer's Disease: Potential Points for Therapeutic Intervention

    Speakers: Erik W.G.M. Boddeke (University Medical Center Groningen, The Netherlands), Oleg Butovsky (Brigham and Women's Hospital and Harvard Medical School, Boston, MA), Philip L. De Jager (Harvard University and Brigham and Women's Hospital, Boston, MA), Joseph El Khoury (Massachusetts General Hospital and Harvard Medical School, Boston, MA), Miriam Merad (Icahn School of Medicine at Mt. Sinai, New York, NY), Michael C. Oldham (University of California, San Francisco, San Francisco, CA), Bin Zhang (Icahn School of Medicine at Mt. Sinai, New York, NY)

    Next generation sequencing of Alzheimer’s disease (AD) progression reveals gene networks within microglial pathways. This symposium focuses on microglia biology, molecular signatures specific to microglial phenotypes, and phenotype modulation.

    Tuesday, December 9, 2014 | 8:00 AM - 5:00 PM

    Diabetic Kidney Disease: Drug Discovery and Clinical Development Challenges

    Speakers: Matthew D. Breyer (Eli Lilly, Indianapolis, IN), Frank C. Brosius (University of Michigan Medical School, Ann Arbor, MI), Benjamin D. Humphreys (Harvard Institutes of Medicine, Boston, MA), Matthias Meier (F. Hoffmann-LaRoche Ltd, Basel, Switzerland), Shahnaz Shahinfar (The Children's Hospital of Philadelphia, Philadelphia, PA), Katalin Susztak (University of Pennsylvania, Philadelphia, PA), Aliza Thompson (US Food & Drug Administration, Silver Spring)

    Identifying and prosecuting drug targets is challenging due to a poor understanding of pathogenesis and few biomarkers. This symposium identifies targets for preventive or therapeutic interventions and discusses challenges in clinical development.

  • Past Events

    Thursday, June 26, 2014 | 7:45 AM - 6:00 PM

    Demyelination and Remyelination: From Mechanism to Therapy

    Keynote Speaker: Robin Franklin (Wellcome Trust – MRC Cambridge Stem Cell Institute, University of Cambridge)

    This translational conference will highlight biological and clinical findings in myelin development, new techniques for brain imaging and for screening molecular targets, and novel therapeutics that promote remyelination.

    Monday, June 9, 2014 | 10:00 AM - 3:15 PM

    2014 Ross Prize in Molecular Medicine: Advances in Immunomodulation

    Featured Speakers: John J. O'Shea (National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH), James P. Allison (The University of Texas MD Anderson Cancer Center), Louis M. Staudt (National Cancer Institute, National Institutes of Health), Charles A. Dinarello (University of Colorado at Denver)

    This symposium will honor Dr. John O'Shea, the recipient of the 2014 Ross Prize in Molecular Medicine, in recognition of his discoveries in immunology and cytokine biology.

    Tuesday, June 3, 2014 | 9:30 AM - 2:30 PM

    Chemical Biology Discussion Group Year-End Symposium

    Keynote Speaker: Michael Marletta (The Scripps Research Institute)

    The Chemical Biology Discussion Group brings together chemists and biologists interested in discussing the latest breakthroughs. The year-end meeting features keynote speaker Michael Marletta of the Scripps Research Institute and a poster session.

    Monday, June 2, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Keynote Speaker: Julie Cooper (National Cancer Institute, NIH)
    Speakers: Akiko Inagaki (Petrini Lab, Memorial Sloan-Kettering Cancer Center), Isabel Lam (Keeney Lab, Memorial Sloan-Kettering Cancer Center), Dongxu Lin (King Lab, Yale University), Mahesh Ramamoorthy (Smith Lab, NYU Langone Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

  • Publications 

    eBriefing

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation), Kevin J. Lee (Lawrence Ellison Foundation), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing explores advances in the science of aging and in drug discovery for Alzheimer's and other neurodegenerative diseases.

    Annals

    The Year in Immunology

    Edited by Noel R. Rose (Johns Hopkins University, Baltimore, Maryland)

    This sixth installment of The Year in Immunology series focuses on myeloid cells and inflammation.

    Volume 1319

    eBriefing

    Malaria 2014: Advances in Pathophysiology, Biology, and Drug Development

    Organizers: Johanna P. Daily (Albert Einstein College of Medicine), David A. Fidock (Columbia University Medical Center), and Jennifer Henry (The New York Academy of Sciences)
    Keynote Speakers: Jane M. Carlton (New York University), Rick M. Fairhurst (National Institute of Allergy and Infectious Diseases, NIH), and Terrie E. Taylor (Michigan State University)

    This eBriefing highlights a symposium held on World Malaria Day to examine breakthroughs in pathophysiology, drug development, and pre-erythrocytic and liver-stage biology.

    eBriefing

    Affective Disorders: Qatar Clinical Neuroscience Conference

    Chairs: Matthew E. Fink (Weill Cornell Medical College), Javaid I. Sheikh (Weill Cornell Medical College in Qatar), Melanie Brickman Stynes (The New York Academy of Sciences), and Brooke Grindlinger (The New York Academy of Sciences)

    This eBriefing highlights research on affective disorders, debilitating mood-related psychiatric illnesses such as depression and bipolar disorder that result from an intrinsic or chronic dysfunction of the brain, either within the cells or in their connectivity.

  • Podcasts

    Podcast
    September 10, 2010

    What Makes Us Wise?

    Can we all be wise old owls? Science journalist Stephen Hall and neuroscientist Andre Fenton dissect what we call wisdom, from the neurons in our brain, to the social constructs behind it.

    Download (22 MB, 00:42:32)
    Podcast
    July 30, 2010

    Oxidative Stress

    Foods high in antioxidants are believed to fight oxidative stress. But what is oxidative stress? Two scientists from a recent NYAS conference break it down and discuss whether antioxidants have superpowers.

    Download (12 MB, 00:18:37)
    Podcast
    July 2, 2010

    What's that Smell?

    Biologist Stewart Firestein and world-renowned perfumer Christophe Laudamiel team up to tackle the science of smell.

    Download (32 MB, 00:49:12)
    Podcast
    April 2, 2010

    More than a Yogurt Cup

    Delve into the world of prebiotic and probiotic science. We talk to three people in the field and learn why keeping the good microbes in our bodies happy means a lot for health.

    Download (14 MB, 00:21:21)
  • Webinar Archives

    Webinar Archive
    February 23, 2010

    Metabotropic Glutamate Receptors: Translation from Discovery to Clinical Trials

    Researchers met to discuss advances in basic and translational research on metabotropic glutamate receptors, which are promising targets in drug discovery for CNS diseases and other illnesses.

    Webinar Archive
    October 27, 2009

    Is Alzheimer's Disease Type 3 Diabetes?

    What is the connection between dysregulated neuronal insulin signaling and Alzheimer's disease? In a recent Academy webinar, some researchers argued that the neurodegenerative disease should be considered a type of diabetes.

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.