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  • Cell & Molecular Biology

  • Events 

    Tuesday, September 30, 2014 | 8:30 AM - 5:00 PM

    Elucidating GPCR Functional Selectivity: Novel Opportunities for Drug Development

    Keynote Speaker: Nobel Laureate Robert J. Lefkowitz (Duke University Medical Center)
    Speakers: John A. Allen (Pfizer), Laura Bohn (The Scripps Research Institute - Florida), Marc G. Caron (Duke University Medical Center), Jonathan A. Javitch (Columbia University and New York State Psychiatric Institute), Terry Kenakin (University of North Carolina School of Medicine), Bryan L. Roth (University of North Carolina School of Medicine), JoAnn Trejo (University of California, San Diego), Jonathan D. Violin (Trevena Inc.)

    Hear academic, industry, basic and translational researchers, including Nobel Laureate Robert Lefkowitz (Duke University Medical Center) and discuss the development of functionally selective GPCR-biased ligands for CV and CNS disease drug discovery.

    Monday, October 6, 2014 | 1:30 PM - 4:30 PM

    Genome Integrity Discussion Group Meeting

    Speakers: Jane Skok (NYU), Agnel Sfeir (NYU), Eli Rothenberg (NYU), Lorraine Symington (Columbia University Medical Center)

    The Genome Integrity Discussion Group provides a forum for interactions between basic and clinical research groups working on chromosome biology and function, and at the interface between chromosome integrity and onset and progression of malignancy.

    Thursday, October 9, 2014 | 8:00 AM - 4:00 PM

    Targeting Key Vulnerabilities in Pancreatic Cancer

    Keynote Speakers: Neesha Dhani (Princess Margaret Hospital, Toronto), Steven D. Leach (Memorial Sloan Kettering Cancer Center)
    Speakers: Gregory Beatty (University of Pennsylvania Perelman School of Medicine), Mikala Egeblad (Cold Spring Harbor Laboratory), Douglas T. Fearon (Weill Cornell Medical College and Cold Spring Harbor Laboratory), Costas A. Lyssiotis (Weill Cornell Medical College ), George Miller (NYU Langone Medical Center), Michael Ports (Gilead Sciences)

    Pancreatic cancer patients currently have limited therapeutic options. This symposium explores breakthroughs in the pathogenesis and progression of pancreatic cancer, and efforts to exploit key vulnerabilities for novel therapeutic interventions.

    Tuesday, October 28, 2014 | 8:30 AM - 5:00 PM

    Pharmacologic Resolution of Inflammation as a Novel Therapeutic Approach

    Speaker: Michael S. Conte (University of California-San Francisco), Milan Fiala (David Geffen School of Medicine at UCLA), Gabrielle Fredman (Columbia University), Bruce Levy (Harvard University, Brigham and Women's Hospital), Dipak Panigrahy (Beth Israel Deaconess Medical Center, Harvard Medical School), Mauro Perretti (Queen Mary University of London), Charles N. Serhan (Brigham & Women's Hospital, Harvard Medical School), Patricia J. Sime (University of Rochester School of Medicine), Rudolph E. Tanzi (Massachusetts General Hospital)

    Uncontrolled, chronic inflammation plays a key role in the progression of many diseases, and elucidation of biochemical pathways provides novel targets. This symposium reviews discoveries, approaches and opportunities for treatment and prevention.

    Monday, November 3, 2014 | 8:00 AM - 4:30 PM

    Gene Network Changes in Alzheimer's Disease: Potential Points for Therapeutic Intervention

    Speakers: Erik W.G.M. Boddeke (University Medical Center Groningen, The Netherlands), Oleg Butovsky (Brigham and Women's Hospital and Harvard Medical School, Boston, MA), Philip L. De Jager (Harvard University and Brigham and Women's Hospital, Boston, MA), Joseph El Khoury (Massachusetts General Hospital and Harvard Medical School, Boston, MA), Miriam Merad (Icahn School of Medicine at Mt. Sinai, New York, NY), Michael C. Oldham (University of California, San Francisco, San Francisco, CA), Bin Zhang (Icahn School of Medicine at Mt. Sinai, New York, NY)

    Next generation sequencing of Alzheimer’s disease (AD) progression reveals gene networks within microglial pathways. This symposium focuses on microglia biology, molecular signatures specific to microglial phenotypes, and phenotype modulation.

  • Past Events

    Monday, September 15, 2014 | 12:00 PM - 4:00 PM

    Click Chemistry in Biology and Medicine: New Developments and Strategies

    Keynote Speakers: Jim Paulson (The Scripps Research Institute), K. Barry Sharpless (The Scripps Research Institute)
    Speakers: Yimon Aye (Cornell University), David A. Spiegel (Yale University), Mingxuan Wu (Princeton University), Peng Wu (Albert Einstein College of Medicine)

    Click chemistry offers a reliable method for discovering chemical connectivity, with great potential in drug discovery and biomedical research. This symposium explores recent developments that offer new technologies for disease diagnosis and therapy.

    Thursday, September 11, 2014 | 8:00 AM - 2:00 PM

    From Bacterial Immunity to Genome Editing: The 2014 Dr. Paul Janssen Award Symposium

    Featuring Award Winners: Emmanuelle Charpentier (Helmholtz Centre for Infection Research) and Jennifer Doudna (Howard Hughes Medical Institute/University of California, Berkeley)

    Honor Drs. Emmanuelle Charpentier and Jennifer Doudna, recipients of the 2014 Dr. Paul Janssen Award for Biomedical Research.

    Thursday, June 26, 2014 | 7:45 AM - 6:00 PM

    Demyelination and Remyelination: From Mechanism to Therapy

    Keynote Speaker: Robin Franklin (Wellcome Trust – MRC Cambridge Stem Cell Institute, University of Cambridge)

    This translational conference will highlight biological and clinical findings in myelin development, new techniques for brain imaging and for screening molecular targets, and novel therapeutics that promote remyelination.

    Monday, June 9, 2014 | 10:00 AM - 3:15 PM

    2014 Ross Prize in Molecular Medicine: Advances in Immunomodulation

    Featured Speakers: John J. O'Shea (National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH), James P. Allison (The University of Texas MD Anderson Cancer Center), Louis M. Staudt (National Cancer Institute, National Institutes of Health), Charles A. Dinarello (University of Colorado at Denver)

    This symposium will honor Dr. John O'Shea, the recipient of the 2014 Ross Prize in Molecular Medicine, in recognition of his discoveries in immunology and cytokine biology.

  • Publications 

    eBriefing

    Demyelination and Remyelination: From Mechanism to Therapy

    Keynote Speaker: Robin Franklin (Wellcome Trust – MRC Cambridge Stem Cell Institute, University of Cambridge)

    This eBriefing highlights biological and clinical findings in remyelination. It also features new techniques for imaging myelin and screening molecular targets, as well as therapeutics that promote remyelination.

    Annals

    Antimicrobial Therapeutics Reviews: Infectious Diseases of Current and Emerging Concern

    Edited by Karen Bush (Indiana University)

    The forth installment of this annual reviews series discusses the impact of infectious diseases (including carbapenem-resistant Enterobacteriaceae, tuberculosis, typhoid, influenza, and dengue) on the health of populations worldwide.

    Volume 1323

    eBriefing

    Advances in Immunomodulation: The 2014 Ross Prize in Molecular Medicine

    Speakers: James P. Allison (University of Texas MD Anderson Cancer Center), Charles A. Dinarello (University of Colorado–Denver), and John J. O'Shea (National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH)

    This eBriefing features John J. O'Shea, recipient of the 2014 Ross Prize in Molecular Medicine for his discoveries in immunology and cytokine biology.

    eBriefing

    The Biology of Aging: Novel Drug Targets for Neurodegenerative Disease

    Organizers: Howard Fillit (Alzheimer's Drug Discovery Foundation), Kevin J. Lee (Lawrence Ellison Foundation), and Jennifer Henry (The New York Academy of Sciences)

    This eBriefing explores advances in the science of aging and in drug discovery for Alzheimer's and other neurodegenerative diseases.

  • Podcasts

    Podcast
    September 10, 2010

    What Makes Us Wise?

    Can we all be wise old owls? Science journalist Stephen Hall and neuroscientist Andre Fenton dissect what we call wisdom, from the neurons in our brain, to the social constructs behind it.

    Download (22 MB, 00:42:32)
    Podcast
    July 30, 2010

    Oxidative Stress

    Foods high in antioxidants are believed to fight oxidative stress. But what is oxidative stress? Two scientists from a recent NYAS conference break it down and discuss whether antioxidants have superpowers.

    Download (12 MB, 00:18:37)
    Podcast
    July 2, 2010

    What's that Smell?

    Biologist Stewart Firestein and world-renowned perfumer Christophe Laudamiel team up to tackle the science of smell.

    Download (32 MB, 00:49:12)
    Podcast
    April 2, 2010

    More than a Yogurt Cup

    Delve into the world of prebiotic and probiotic science. We talk to three people in the field and learn why keeping the good microbes in our bodies happy means a lot for health.

    Download (14 MB, 00:21:21)
  • Webinar Archives

    Webinar Archive
    February 23, 2010

    Metabotropic Glutamate Receptors: Translation from Discovery to Clinical Trials

    Researchers met to discuss advances in basic and translational research on metabotropic glutamate receptors, which are promising targets in drug discovery for CNS diseases and other illnesses.

    Webinar Archive
    October 27, 2009

    Is Alzheimer's Disease Type 3 Diabetes?

    What is the connection between dysregulated neuronal insulin signaling and Alzheimer's disease? In a recent Academy webinar, some researchers argued that the neurodegenerative disease should be considered a type of diabetes.

    Webinar Archive
    April 28, 2009

    Protein Kinases: Structure-Guided Drug Discovery

    Protein kinases play a key role in almost every major pathway in eukaryotic cells. Structural approaches, including a new method called fragment-based drug design, are identifying potential targets against diseases including cancer.

  • Translational Medicine Initiative

    Macy FoundationThe Translational Medicine Initiative represents a three-year partnership between the New York Academy of Sciences and the Josiah Macy, Jr. Foundation to support the translation of basic science research into clinical applications.

    Learn more at www.nyas.org/TransMed.