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COLUMNS Field Notes • The Wild, Wild Pest A gang of crude yet deadly viruses, on the run from domestic animals, is slaughtering wild species worldwide CYNTHIA MILLS
ESSAYS & COMMENT Just Cause As the human genome is decoded, artists are seizing the stuff of the genetic revolution and grappling with its dilemmas EMILY LABER
FEATURES Antarctic Dreams Deep in the South Polar ice, a new neutrino telescope at last has seen first light. Its targets are the most violent events in the universe FRANCIS HALZEN
Twilight on Bald Mountain Time is running out for a rare habitat in southern Appalachia. Would saving it be an unnatural act? TRAVIS W. KNOWLES
On Common Ground • Layering Does the "naked truth" always lie at the bottom? PHOTOGRAPH BY ROSAMOND PURCELL
TEXT BY STEPHEN JAY GOULD
MIRACLES OF RARE DEVICE New tools, not new ideas, will usher in tomorrow's scientific marvels PHOTOGRAPH BY ROSAMOND PURCELL FREEMAN J. DYSON
REVIEWS Cover Story • The Odd Couple From geek chic to information appliances to empathic machines: the struggle for people-friendly computers continues MARGARET WERTHEIM
Books in Brief • The Vision Thing PLUS: A history of twentieth-century physics LAURENCE A. MARSCHALL
DEPARTMENTS Initial Conditions • Editor's Notebook God, Technology And Postmodernism PETER G. BROWN
Peer Review Letters from Readers
Working Hypotheses • Ethics Smuggle Them In? RODNEY W. NICHOLS
Quanta Metamorphoses, Burning Issue, One Hand is Better than Two, Q-bits
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