Cancer & Signaling Discussion Group
The genetic and epigenetic alterations that evolve during tumorigenesis ultimately conspire to perturb the complex systems of molecular signalling pathways. By understanding how pathways are regulated normally, and how they are dysregulated in cancer, scientists hope to identify molecular targets that will be receptive to therapeutic intervention.
The Cancer & Signaling Discussion Group provides a forum for exploring the molecular networks that play a role in cancer predisposition, initiation, and progression. The group also focuses on the responses of tumors to therapeutic intervention, including through feedback loops, acquired alterations, and interaction with the microenvironment. Meetings of the group focus on specific themes related to signal transduction dysregulation in oncogenesis, and cover basic, translational, clinical, and diagnostic aspects of the field.