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E-Briefing Archive

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Overview eBriefings are online multimedia reports documenting select Academy events that took place from 2010-2022. These reports provide an overview of the event, biographies of speakers and panelists, video clips of speaker presentations and other supporting resources.  Past event recaps are now published on the Academy Blog and select events are available on-demand for a […]

Addressing Global Calcium Deficiency

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An estimated 3.5 billion people around the globe are at risk of calcium deficiency due to inadequate dietary intake. While primarily associated with bone health, calcium has also been shown to reduce the risk of preeclampsia and associated complications, which are leading causes of maternal morbidity and mortality. Populations in low- and middle- income countries […]

Multiple Micronutrient Supplements in Pregnancy

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Following the release of the 2016 WHO Guidelines for Antenatal Care, The New York Academy of Sciences assembled a scientific task force comprised of international experts in micronutrient deficiencies, public health, nutrition, pediatrics and health economics to: The findings from the first phase of this initiative show that substantial benefits may be expected, in terms […]

Inside the Quest for a COVID-19 Vaccine

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When SARS-CoV-2—the respiratory virus that causes COVID-19—first emerged, most people did not anticipate that it would result in a global public health disaster. COVID-19 rapidly spread from person to person across all borders, bringing hospitals to the brink of collapse, causing a devastating loss of life, and shutting down global economies.

Neuroplasticity, Neuroregeneration, and Brain Repair

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Many promising strategies for promoting neuroregeneration have emerged in the past few years, but a further research push is needed for these ideas to be translated into therapies for neurodegenerative diseases.

On June 13–14, a symposium presented by Eli Lilly and Company and The New York Academy of Sciences brought together academic and industry researchers working on multiple neurodegenerative diseases as well as clinicians and government stakeholders to discuss cutting edge basic and clinical research on neuroregeneration and neurorestoration. Topics included neuronal plasticity, inflammation, glial cell function, autophagy, and mitochondrial function, as well as analysis of recent drug development failures and how to move forward from them.

Equivalence of Complex Drug Products: Scientific and Regulatory Challenges

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Biotechnology and nanotechnology have given rise to a growing number of innovator-driven complex drug products and their copy versions. Biologics exemplify one category of complex drugs, but there also exist non-biological complex drug products (NBCDs), including many nanomedicines such as iron-carbohydrate complexes, several drug carrying liposomes or emulsions, and glatiramoids. These products are difficult to characterize—often the key features for efficacy and safety are not well understood. These factors pose unique challenges for pharmaceutical companies and regulatory agencies when comparing generic complex drugs to their branded counterparts.

Disease Drivers of Aging: The 2016 Advances in Geroscience Summit

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The processes associated with aging may be risk factors for age-related diseases. Conversely, many age-related chronic diseases accelerate aging. However, because most research is focused on specific diseases, the broad mechanisms of disease as a driver of aging have not been well studied. Understanding how disease drives aging could not only help people live longer but also improve health and quality of life during old age.

Grantsmanship for Postdocs: Navigating the K99/R00 Award

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According to the NIH, less than a quarter of U.S.-trained biomedical PhD graduates obtain tenure or tenure-track academic positions. The number of postdocs in the sciences continues to grow—in the U.S. there were 2.5 times more postdocs in 2012 than in 2000—while the number of tenure and other full-time faculty positions has plateaued.

Not surprisingly, postdocs who have independent funding are more competitive in the academic job market. On November 3, 2015, the Academy’s Science Alliance presented a seminar on grant writing, specifically applied to the NIH K99/R00 career transition award for postdocs. This year’s Grantsmanship for Postdocs event featured a presentation by Jaime S. Rubin from Columbia University and a panel of postdoctoral fellows and junior faculty who have successfully applied for K99/R00 funding. The information Rubin provided on the K99/R00 funding mechanism is one component of the material she discusses in her Columbia University graduate-level course, “Funding and Grantsmanship for Research and Career Development Activities.”

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