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Addiction Reviews 2008

Edited by Edited by George R. Uhl (National Institutes of Health Intramural Research Program, National Institute on Drug Abuse)
Addiction Reviews 2008

Published: October 2008

Volume 1141

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This is the inaugural volume for an annual review serving all aspects of addiction research and treatment. Each year in-depth scholarly reviews of the most timely and important topics in this field will be discussed.


  • N. Volkow, Introduction

Mechanisms of Addiction

  • Trevor Robbins, K. D. Ersche, and B. J. Everitt, Learning, Memory and the Development and Persistence of Addictions
  • Anna M. Lee and Robert O. Messing, Protein Kinases and Addiction
  • Melinda E. Lull, Willard M. Freeman, Kent E. Vrana, and Deborah C. Mash, Correlating Human and Animal Studies of Cocaine Abuse and Gene Expression
  • Minae Niwaa, Yijin Yanb, and Toshitaka Nabeshima, Genes and Molecules That Can Potentiate or Attenuate Models of Psychostimulant Dependence: Relevance of Data from Animal Models to Human Addiction
  • Minoru Narita, Masami Suzuki, Naoko Kuzumaki, Mayumi Miyatake, and Tsutomu Suzuki, Implication of Activated Astrocytes in the Development of Drug Dependence: Differences between Methamphetamine and Morphine

Related Conditions

  • Raita Sinha, Chronic Stress, Drug Use, and Vulnerability to Addiction
  • Francis Joseph McClernon and Scott Haden Kollins, ADHD and Smoking: From Genes to Brain to Behavior
  • David Graham and Aaron L. Cardon, An Update on Substance Abuse and Treatment Following Traumatic Brain Injury
  • Dany Gaillard, Patricia Pasilly-DeGrace, and Philippe Besnard, Molecular Mechanisms of Fat Preference and Overeating


  • Leonard L. Howell and Kevin S. Murnane, Nonhuman Primate Neuroimaging and the Neurobiology of Psychostimulant Addiction
  • Steven Berman, Joseph O’Neill, Scott Fear, George Bartzokis, and Edythe D. London, Abuse of Amphetamines and Structural Abnormalities in Brain


  • F. Ivy Carroll, Antagonists at Metabotropic Glutamate Receptor Subtype 5: Structure Activity Relationships and Therapeutic Potential for Addiction
  • Jed E. Rose, Disrupting Nicotine Reinforcement: From Cigarette to Brain
  • Frank M. Orson, Berma M. Kinsey, Rana A. K. Singh, Yan Wu, Tracie Gardner, and Thomas R. Kosten, Substance Abuse Vaccines
  • Martina Reske and Martin P. Paulus, Predicting Treatment Outcome in Stimulant Dependence
  • Curtis Wright IV, Sidney Schnoll, and David Bernstein, Risk Evaluation and Mitigation Strategies (REMS) for Drugs with Abuse Liability: Public Interest, Special Interest, Conflicts of Interest


  • Lin Lu and Xi Wang, Drug Addiction in China


  • George R. Uhl, Tomas Drgon, Catherine Johnson, C. Y. Li, Carlo Contoreggi, Judith Hess, Daniel Naiman, and Qing-Rong Liu, Molecular Genetics of Addiction and Related Heritable Phenotypes: Genome-Wide Association Approaches Identify “Connectivity Constellation” and Drug Target Genes with Pleiotropic Effects