The papers in the 2014 edition of Addiction Reviews cover a range of timely and relevant subjects. For example, Jentsch and colleagues provide perspective on the ways in which impulsivity has been approached in relationship to addictions. Brunzell and colleagues focus on the ways in which homo- and heteromultimeric acetylcholine receptors with differing subunit composition provide selective targets for antismoking therapeutics. In another paper, Clark provides a timely perspective on gambling as an addiction. And Bickel and McClure provide a novel synthesis that springs from their longstanding work in relation to components of more automatic/habitual versus deliberative contributions to addictions and their treatment. Three papers in this volume approach translational issues from distinct and interesting perspectives. For example, Gorelick and colleagues assemble the nascent material on the utility of transcranial magnetic stimulation for addiction, in ways that should help translation of these approaches to more frequent use and/or in specific groups of addicted individuals. Carroll deals directly with important questions related to ways in which apparently efficacious contingency management and cognitive behavioral strategies translate into broader clinical practice with modest frequency. The third translational paper, from Gastfriend, provides a novel pharma perspective on the economics of anti-addiction therapeutics.