Although Alzheimer's disease was formally described as a distinct clinical-neuropathological entity at the turn of the century, the intense research effort on this disorder was not mobilized until the 1970s. In the last 20 years, a rich array of new ideas on diagnosis, treatment, risk factors, and possible cause(s) have emerged. The wealth of new information has led to the formulation of many current theories. However, little attempt has been made to integrate the different ideas or to establish a coherent link among the distinct theories, which at times appear to be odds with one another and/or with the available data. This unique volume was designed to provide a comprehensive and critical evaluation of all major theoretical perspectives on Alzheimer's disease. Contributors were selected for their thoughtful and broad viewpoints on Alzheimer's disease; each was invited to prepare a short comprehensive paper on the major assumptions and predictions of their hypothesis, which should be incorporated into a \"new unifying theory\" of the disease.
This volume is out of print.