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Annals

Effects of Genome Structure and Sequence on Variation and Evolution

Edited by Edited by Lynn H. Caporale
Effects of Genome Structure and Sequence on Variation and Evolution

Published: September 2012

Volume 1267

A collection of papers detailing the latest insights into genomic variation and evolution.
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The mechanisms that govern the evolution of the genome are not well understood, yet great strides have been made to identify and target areas of inquiry that will help to elucidate the ways in which genetic change is regulated. Emerging from the innovative work of multidisciplinary experts representing the spectrum of DNA research, this volume revolves around the overarching theme of DNA replication and repair fidelity within the framework of evolution. This collection of papers highlights notable topics such as the influence of regional specificity in variation of distinct classes of DNA, the significance of sequence organization and relationships in genomic evolution, novel methods of sequence analysis, and the potential ramifications of these processes in cancer and tumor progression.

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