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Edited by Edited by Willem Nieuwenhuizen (Gaubius Laboratory, TNO-PG, Leiden, The Netherlands), Michael W. Mosesson (The Blood Research Institute, Milwaukee, WI), and Moniek P.M. de Maat (Gaubius Laboratory, TNO Prevention and Health)
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Published: June 2001

Volume 936

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Fibrinogen is a circulating multifunctional blood protein of hepatic origin which, upon proteolytic conversion to fibrin by thrombin, polymerizes to form a fibrin clot, which comprises the main structural element of the intravascular thrombus. Specific study areas of fibrinogen include hemostasis and thrombosis, fibrinolysis, wound healing, angiogenesis, inflammation, cell migration, tumor growth and metastatic implantation.

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