Glutamate and Disorders of Cognition and Motivation

Edited by Edited by Bita Moghaddam (Yale University School of Medicine, New Haven, CT) and Marina E. Wolf (Chicago Medical School, North Chicago, IL)
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Glutamate and Disorders of Cognition and Motivation

Published: November 2003

Volume 1003

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Although glutamate-mediated neurotransmission has long been implicated in neurodegenerative disorders, the major focus of research on cognitive, affective, and addictive disorders has been on monoamine (dopamine, serotonin, norephinephrine) systems in the brain. About 10–15 years ago, a few scientists began studying the possible role of glutamate in these disorders, led by awareness of glutamate's importance in cortical function and of the role of glutamatergic projections in governing the activity of monoaminergic neurons. Recent years have witnessed tremendous advances in our understanding of glutamatergic involvement in schizophrenia and drug abuse. This volume presents the latest research in both basic and clinical fields and will facilitate interactions among diverse disciplines and between basic and clinical scientists.