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Mitochondria and Oxidative Stress in Neurodegenerative Disorders

Edited by Edited by Gary E. Gibson and Rajiv R. Ratan (Weill Medical College of Cornell University, Burke Medical Research Institute, White Plains, New York) and M. Flint Beal (Weill Medical College of Cornell University, New York, New York)
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Mitochondria and Oxidative Stress in Neurodegenerative Disorders

Published: December 2008

Volume 1147

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Our understanding of the interaction of mitochondria with other cellular organelles, with transcription, and in the ability to detect oxidative modification of macromolecules has improved significantly in the past decade. Moreover, the roles of mitochondria and oxidative stress are better defined in the pathophysiology of neurodegenerative disorders. This volume provides the most current information in basic, clinical, and translational research on aspects of mitochondrial function and their relationship to age-related neurodegenerative diseases and their treatment.