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Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways

Edited by Edited by Marc Diederich (Fondation "Recherche sur le Cancer et les Maladies du Sang" Laboratoire de Biologie Moléculaire et Cellulaire du Cancer Hôpital Kirchberg, Luxembourg)
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Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways

Published: August 2009

Volume 1171

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Apoptosis is a highly regulated mechanism by which cells undergo cell death in an active way. As one of the most challenging tasks concerning cancer is to induce apoptosis in malignant cells, researchers increasingly focus on natural products to modulate apoptotic signaling pathways. This volume reviews the main effects of natural compounds on the different apoptotic signaling pathways, including the intrinsic and extrinsic apoptosis pathways, the NF-kB-mediated pathway, the PI3K/Akt signaling, and other main pathways.