In an effort to support global initiatives to contain the spread of the new coronavirus (COVID-19), the Academy is presenting Spring 2020 events through online platforms and some of our previously scheduled events are being postponed to a later date. Please check our events listing for the latest information and contact our Customer Service team with any additional questions. For Academy programs and resources about COVID-19, click here.

We are experiencing intermittent technical difficulties. At this time, you may not be able to log in, register for an event, or make a donation via the website. We appreciate your patience, and apologize for any inconvenience this may cause.

This site uses cookies.
Learn more.


This website uses cookies. Some of the cookies we use are essential for parts of the website to operate while others offer you a better browsing experience. You give us your permission to use cookies, by continuing to use our website after you have received the cookie notification. To find out more about cookies on this website and how to change your cookie settings, see our Privacy policy and Terms of Use.


Special Issue: Cooley's Anemia

Edited by

Annals of the New York Academy of Sciences editorial staff

Special Issue: Cooley's Anemia

Published: March 2016

Volume 1368

Published since 1824, Annals of the New York Academy of Sciences is the Academy’s premier scientific publication.

Learn More

Thalassemia is one of the most common genetic blood disorders and results from deficient synthesis of one or more of the globin subunits of hemoglobin—the protein molecule in red blood cells that is necessary for oxygen transport in the blood. Patients affected by the most severe form of the disease (thalassemia major or Cooley’s anemia) develop life-threatening anemia within the first 2 years of life and require lifelong blood transfusions for survival, in combination with chelation therapy to prevent or reduce progressive iron overload. To provide a forum for discussion of recent research and clinical advancements in understanding and treating thalassemia, the New York Academy of Sciences and the Cooley’s Anemia Foundation jointly presented the “Tenth Cooley’s Anemia Symposium” on October 18–22, 2015 in Rosemont, Illinois. This Annals issue presents a collection of papers stemming from this symposium. The papers, written by basic scientists, clinical investigators, and clinicians, cover a range of topics, including the biology of globin gene regulation and fetal hemoglobin induction; the evolving areas of stem cell transplant, gene therapy strategies, and gene editing; the biology of iron regulation and possible therapeutic interventions in the hepcidin regulatory system; and clinical issues in thalassemia treatment and imaging.