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Special Issue: Countermeasures Against Chemical Threats

Edited by

Jeffrey D. Laskin (Rutgers University)

Special Issue: Countermeasures Against Chemical Threats

Published: November 2020

Volume 1479

Published since 1824, Annals of the New York Academy of Sciences is the Academy’s premier scientific publication.

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Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates

Janice E. Chambers, Edward C. Meek


Diagnostics and treatment of nerve agent poisoning—current status and future developments

Niko Amend, Karin V. Niessen, Thomas Seeger, Timo Wille, Franz Worek, Horst Thiermann


Hyaluronan and halogen‐induced airway hyperresponsiveness and lung injury

Ahmed Lazrak, Weifeng Song, Ting Zhou, Saurabh Aggarwal, Tamas Jilling, Stavros Garantziotis, Sadis Matalon



Sex as a biological variable in the rat model of diisopropylfluorophosphate‐induced long‐term neurotoxicity

Meghan Gage, Madison Golden, Marson Putra, Shaunik Sharma, Thimmasettappa Thippeswamy


Development of mouse models for the study of chloropicrin and hydrogen fluoride ocular injury

Robert D. Causey, Jeffrey A. Koenig, Jeffrey J. Autrey, Kevin J. McGowan, Amber M. Gomez, John G. Lehman, Albert L. Ruff


Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate‐induced long‐term neurotoxicity in the rat model

Marson Putra, Meghan Gage, Shaunik Sharma, Cara Gardner, Grace Gasser, Vellareddy Anantharam, Thimmasettappa Thippeswamy


Delayed midazolam dose effects against soman in male and female plasma carboxylesterase knockout mice

Erica Kundrick, Brenda Marrero‐Rosado, Michael Stone, Caroline Schultz, Katie Walker, Robyn B. Lee‐Stubbs, Marcio de Araujo Furtado, Lucille A. Lumley


Antidotal effects of methylene blue against cyanide neurological toxicity: in vivo and in vitro studies

Philippe Haouzi, Marissa McCann, JuFang Wang, Xue‐Qian Zhang, Jianliang Song, Ilker Sariyer, Diane Langford, Maryline Santerre, Nicole Tubbs, Annick Haouzi‐Judenherc, Joseph Y. Cheung


Electroencephalographic analysis in soman‐exposed 21‐day‐old rats and the effects of midazolam or LY293558 with caramiphen

Marcio De Araujo Furtado, Vassiliki Aroniadou‐Anderjaska, Taiza H. Figueiredo, James P. Apland, Maria F. M. Braga


Alleviation of methyl isocyanate−induced airway obstruction and mortality by tissue plasminogen activator

Heidi J. Nick, Jacqueline S. Rioux, Livia A. Veress, Preston E. Bratcher, Leslie A. Bloomquist, Poojya Anantharam, Claire R. Croutch, Richard S. Tuttle, Eric Peters, William Sosna, Carl W. White


MicroRNA‐mediated inflammation and coagulation effects in rats exposed to an inhaled analog of sulfur mustard

Tapasi Rana, Aamir Ahmad, Iram Zafar, Nithya Mariappan, Darshan Shimoga Chandrashekar, Tariq Hamid, Maroof Husain, Sooryanarayana Varambally, Shama Ahmad, Aftab Ahmad


Intramuscular aminotetrazole cobinamide as a treatment for inhaled hydrogen sulfide poisoning in a large swine model

Tara B. Hendry‐Hofer, Patrick C. Ng, Alison M. McGrath, David Mukai, Matthew Brenner, Sari Mahon, Joseph K. Maddry, Gerry R. Boss, Vikhyat S. Bebarta


A sex‐balanced rodent model for evaluating phosphine inhalation toxicity

Wing Y. Tuet, Michelle C. Racine, Laura Jennings, Samuel A. Pierce, Justin Tressler, Bryan J. McCranor, Benjamin Wong


Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O‐(2‐[18F]fluoroethyl)‐O‐(p‐nitrophenyl)methylphosphonate [18F]‐VXS

Thomas R. Hayes, Joseph E. Blecha, Chih‐Kai Chao, Tony L. Huynh, Henry F. VanBrocklin, Kurt R. Zinn, Palmer W. Taylor, John M. Gerdes, Charles M. Thompson


Methylene blue and monosodium glutamate improve neurologic signs after fluoroacetate poisoning

Vanessa E. DeLey Cox, Matthew A. Hartog, Erin Pueblo, Michelle Racine, Laura Jennings, Justin Tressler, Wing Y. Tuet, Samuel Stone, Samuel A. Pierce, Lily Thompson, Aliyah Dukes, Heidi Hoard‐Fruchey, Benjamin Wong, Bryan J. McCranor


Cutaneous lewisite exposure causes acute lung injury

Shajer Manzoor, Nithya Mariappan, Iram Zafar, Chih‐Chang Wei, Aamir Ahmad, Ranu Surolia, Jeremy B. Foote, Anupam Agarwal, Shama Ahmad, Mohammad Athar, Veena B. Antony, Aftab Ahmad


Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure

Matthew D. McGraw, So‐Young Kim, Carl W. White, Livia A. Veress