The amygdala is a brain area that has recently become one of the hottest topics in neuroscience. The papers in this volume provide information on the basic characteristics of amygdala function including neuroanatomical, electrophysiological, behavioral, and imaging studies in animals and humans. Papers also examine whether the amygdala is an integrator or repositor of memories; the role of the amygdala in withdrawal from drugs of abuse; and the amygdala's role in cardiovascular control, stress, and pain. This information is integrated with recent findings in clinical human diseases (Alzheimer's, epilepsy, anxiety, depression, schizophrenia, and panic disorder) in which the function of the amygdala is compromised. Pharmacological information is presented to provide a foundation for designing drugs for treatment of pathologic disorders of the amygdala.