Therapeutic Oligonucleotides

Edited by Edited by Y.S. Cho-Chung (National Cancer Institute, NIH, Bethesda, Maryland), A. M. Gewirtz (University of Pennsylvania School of Medicine, Philadelphia), and C.A. Stein (Albert Einstein-Montefiore Cancer Center, Bronx, New York)
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Therapeutic Oligonucleotides

Published: December 2003

Volume 1002

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This book is concerned with various aspects of oligonucleotides including triplex DNA, transcription factor decoy, antisense DNA/RNA, ribozymes, PNA, 2',5'-oligoadenylates, RNAi, and CpG immune-stimulating oligomers, diagnostic oligonucleotide chips (DNA chips), and gene therapy vectors. These oligonucleotides can modulate gene-specific expression within cells and can identify genes involved in diseases. Recent developments in oligonucleotide research have demonstrated the potential utility of oligonucleotides as therapeutic agents, particularly in the treatment of cancer, AIDS, and other diseases.