Annals

Thymosins in Health and Disease

Edited by Edited by Allan L. Goldstein (The George Washington University Medical Center, Washington, DC) and Enrico Garaci (University of Rome “Tor Vergata”, Rome)
Explore the Table of Contents
Thymosins in Health and Disease

Published: September 2007

Volume 1112

Learn More

The thymosins are a family of biologically active peptides with hormone-like properties that were first isolated in 1966. Since that time, significant progress has been made in our understanding of the role of these molecules in immunity and the nature of the physiological processes they regulate. The physiological processes that these peptides affect include stimulation or suppression of immune responses, regulation of actin dynamics and cell motility, neuroplasticity, repair and remodeling of vessels of the heart and other injured tissues, angiogenesis, and stem cell differentiation. Several of these molecules have also been shown to be useful as molecular markers and as potential diagnostics in areas ranging from cancer and infectious diseases to autoimmune diseases and aging.