Tumor Progression and Therapeutic Resistance

Edited by Edited by Wafik S. El-Deiry (University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania)
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Tumor Progression and Therapeutic Resistance

Published: December 2005

Volume 1059

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A breadth of translational cancer research is addressed in this volume, which includes: the discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays, mechanism determination, target validation, therapeutic window and some progress in clinical trials for more advanced agents and targets.