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eBriefing

Cancer Metabolism and Signaling

Cancer Metabolism and Signaling
Reported by
Pinelopi Kyriazi

Posted August 03, 2018

Presented By

The Cancer Discussion Group

The New York Academy of Sciences

Overview

The study of cancer metabolism is one of the oldest areas of research in cancer biology. Tumors reprogram metabolic and signaling pathways to acquire nutrients, balance oxidative stress and support cell survival. These metabolic changes are considered a hallmark of cancer and they are observed across many types of cancer cells. Recently, metabolites have been shown to play an important role in initiating and advancing tumorigenesis. A better understanding of how malignant cells exploit metabolic pathways to foster their growth, proliferation, and metastasis, can help create new therapeutic strategies. Scientists came together to discuss the intersection between cancer cell metabolism, signaling, and therapeutic interventions on May 24, 2018 at the Cancer Metabolism and Signaling meeting hosted by the Cancer Discussion Group at the New York Academy of Sciences.

Speakers

Lydia Finley, PhD, Memorial Sloan Kettering Cancer Center
Lydia Finley, PhD, Memorial Sloan Kettering Cancer Center
Costas Lyssiotis, PhD, University of Michigan Medical School
Costas Lyssiotis, PhD, University of Michigan Medical School
Heather Christofk, PhD, University of California, Los Angeles
Heather Christofk, PhD, University of California, Los Angeles
Reuben J. Shaw, PhD, The Salk Institute for Biological Studies
Reuben J. Shaw, PhD, The Salk Institute for Biological Studies
Thales Papagiannakopoulos, PhD, New York University School of Medicine
Thales Papagiannakopoulos, PhD, New York University School of Medicine
M. Celeste Simon, PhD, University of Pennsylvania Perelman School of Medicine
M. Celeste Simon, PhD, University of Pennsylvania Perelman School of Medicine
Andrew M. Intlekofer, MD, PhD, Memorial Sloan Kettering Cancer Center
Andrew M. Intlekofer, MD, PhD, Memorial Sloan Kettering Cancer Center
Javier Garcia-Bermudez, PhD, The Rockefeller University
Javier Garcia-Bermudez, PhD, The Rockefeller University
Inna Serganova, PhD, Memorial Sloan Kettering Cancer Center
Inna Serganova, PhD, Memorial Sloan Kettering Cancer Center
Steven Gross, PhD, Weill Cornell Medical Center
Steven Gross, PhD, Weill Cornell Medical Center
Kathryn Wellen, PhD, University of Pennsylvania Perelman School of Medicine
Kathryn Wellen, PhD, University of Pennsylvania Perelman School of Medicine
Sean Morrison, PhD, The University of Texas Southwestern Medical Center
Sean Morrison, PhD, The University of Texas Southwestern Medical Center
Kenneth P. Olive, PhD, Columbia University Irving Medical Center
Kenneth P. Olive, PhD, Columbia University Irving Medical Center
Lewis C. Cantley, PhD, Weill Cornell Medical College
Lewis C. Cantley, PhD, Weill Cornell Medical College
Session 1: Metabolic Drivers of Cancer
Session 2: Data Blitz Presentations
Session 3: Targeting Metabolism in Tumors
Keynote Lecture: PI 3-Kinase and Cancer Metabolism