Biochemical Pharmacology Discussion Group
The New York Academy of Sciences
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DONATEPosted September 09, 2020
Presented By
Biochemical Pharmacology Discussion Group
The New York Academy of Sciences
The stromal microenvironment plays critical roles in tissue homeostasis, wound healing and the inflammatory response. Comprised of fibroblasts, the extracellular matrix, endothelial cells, pericytes, and adipocytes — many elements of the stroma have recently been implicated as important modulators of the shape and intensity of local immune responses. Thus, greater knowledge of the interactions between immune cells and stromal components is critical to understand their roles in both normal and pathological scenarios.
This eBriefing contains the proceeding of the virtual symposium Immune-Stromal Cell Interactions in Wound Healing, Fibrosis and Cancer, which took place on June 9, 2020. The meeting featured discussion of the common mechanisms of reciprocal regulation between stromal constituents and immune cells that may present exciting new therapeutic targets for a variety of diseases including cancer, fibrosis and chronic inflammatory and autoimmune conditions.