In an effort to support global initiatives to contain the spread of the new coronavirus (COVID-19), the Academy is moving to an online platform or postponing all meetings and events intended to be held in person through April 30, 2020. Please check here for more information, including Academy programs on COVID-19, and links to the latest advisories from public health officials.

We are experiencing intermittent technical difficulties. At this time, you may not be able to log in, register for an event, or make a donation via the website. We appreciate your patience, and apologize for any inconvenience this may cause.

This site uses cookies.
Learn more.

×

This website uses cookies. Some of the cookies we use are essential for parts of the website to operate while others offer you a better browsing experience. You give us your permission to use cookies, by continuing to use our website after you have received the cookie notification. To find out more about cookies on this website and how to change your cookie settings, see our Privacy policy and Terms of Use.

eBriefing

Insights into the Resolution of Inflammation

Insights into the Resolution of Inflammation
Reported by
Sara Donnelly

Posted February 25, 2020

Presented By

The New York Academy of Sciences

Overview

Inflammation is a common feature of many widely occurring human diseases. In recent years, our understanding of the molecular mechanisms regulating inflammation has improved dramatically, most notably with the identification of active processes that control the resolution of the inflammatory response. Now, this rapidly evolving field of research – Resolution Pharmacology — promises novel approaches for the treatment of myriad inflammatory diseases. In this webinar, the first in a four-part series, leaders in the field explore recent research on the molecular mechanisms driving the resolution of inflammation and approaches to therapeutically target these pathways in chronic inflammatory and autoimmune diseases.

In This Webinar, You’ll Learn

  • The key steps required for the successful resolution of inflammation.
  • How pro-resolving mediators, including lipoxins, resolvins, maresins, and protectins are biosynthesized and how they regulate resolution.
  • How defects in resolution pathways contribute to chronic autoimmune and inflammatory conditions.
  • Emerging strategies to therapeutically target the resolution of inflammation in diabetes and its associated complications including atherosclerosis, kidney disease, and fibrosis.

Speakers

Charles Serhan, PhD, DSc
Charles Serhan, PhD, DSc

Harvard Medical School

Catherine Godson, PhD, MRIA
Catherine Godson, PhD, MRIA

University College Dublin

Event Sponsors

Insights into Inflammation Resolution

Speakers

Charles Serhan, PhD, DSc

Harvard Medical School

Charles N. Serhan is a leading authority in inflammatory resolution and was first to identify the role of pro-resolving cellular mediators such as resolvins and lipoxins. He is the Simon Gelman Professor of Anesthesia at Harvard Medical School and Professor of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine. He directs the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women’s Hospital. Charles received his BS from Stony Brook University and his doctorate from NYU School of Medicine. He was a post-doctoral fellow at the Karolinska Institutet, Stockholm and joined the faculty at Harvard Medical School in 1987.

Catherine Godson, PhD, MRIA

University College Dublin

Catherine Godson studies the innate immune system and chronic complications of diabetes. Her research on inflammatory processes underlying diabetic complications has led to the identification of several novel therapeutic targets, susceptibility genes and potential modulators of disease. She is Full Professor of Molecular Medicine at University College Dublin (UCD), Director of the UCD Diabetes Complications Research Centre, and visiting Professor at Monash University, Melbourne. She was elected a member of the Royal Irish Academy in 2011 and received the Woman in Science Award of The International Congress of Inflammation, Sydney in 2019, in recognition of "outstanding research and leadership contributions."

Insights into Inflammation Resolution


Charles Serhan (Harvard Medical School) Catherine Godson (University College Dublin)

Further Readings

Serhan

Serhan CN, Levy BD

J Clin Invest. 2018;128(7):2657–2669.

Norris PC, Libreros S, Serhan CN

Sci Adv. 2019 Oct23;5(10):eaax4895

Norris PC, Skulas-Ray AC, Riley I, et al.

Sci Rep. 2018 Dec 21;8(1):18050

Godson

Brennan EP, Cacace A, Godson C

Mol Aspects Med. 2017;58:102–113

Brennan EP, Mohan M, McClelland A, et al.

J Am Soc Nephrol. 2018;29(5):1437–1448