The New York Academy of Sciences
Resolving Inflammation in Cardiovascular Disease
Posted June 18, 2020
Every year in the United States, more than 1.5 million people will suffer from either a heart attack or a stroke. This eBriefing explores the links between chronic inflammation and these conditions and discusses how strategies to resolve inflammation could lead to new therapies.
In This eBriefing, You'll Learn
- Recent clinical data linking chronic inflammation to cardiovascular disease, the leading cause of heart attack and stroke
- How failure to resolve chronic inflammation promotes the development of atherosclerotic cardiovascular disease
- New approaches that modulate the resolution of inflammation and have the potential to provide improved treatments for this widespread condition
Paul Ridker, MD, MPH
Harvard Medical School
Dr. Paul M. Ridker is director of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital (BWH) and the Eugene Braunwald Professor of Medicine at Harvard School of Medicine (HMS). He received his medical degree from HMS and then completed an internal medicine residency and a cardiology fellowship at BWH. Dr. Ridker’s primary research focus has involved inflammatory mediators of heart disease and the molecular and genetic epidemiology of hemostasis and thrombosis, with particular interests in biomarkers for coronary disease, “predictive” medicine, and the underlying causes and prevention of atherosclerotic disease.
Gabrielle Fredman, PhD
Albany Medical College
Gabrielle Fredman received a PhD from Boston University in 2009. She pursued post-doctoral fellowships at Harvard Medical School and Columbia University studying the chemical biology of lipid mediators in the resolution of inflammation with a focus on their actions in atherosclerosis. Dr. Fredman was a recipient of the Young Investigator Award from the Eicosanoid Research Foundation and a finalist for the Irvine Page Award in 2016. She is now an Associate Professor at Albany Medical College. Her research interests include uncovering mechanisms associated with defective resolution of inflammation in atherosclerosis and aging.