Biochemical Pharmacology Discussion Group
The New York Academy of Sciences
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DONATEPosted February 10, 2020
In the last two decades, remarkable advances in 3D culture technology have made organoids possible. Using embryonic or adult mammalian stem cells, researchers worked to achieve tissue-like mimetics that assemble into a relevant tissue-specific structure, taking on the functional properties of organs. Through careful study of the desired functions of a target organ and the implementation of its microstructure, researchers have created organoids that can serve as platforms for high-throughput, multi-scaled drug screening. Organs-on-chips have also been used to model human organ disease and study organ development. Patient-derived organoids hold promise for personalized medicine because they have the potential to indicate individualized predictions of drug response.
Learn more about recent progress in 3D culture technology, the development of organoid protocols and models, and their application in this summary of our November 12, 2019 symposium.