Anatomy of a Tremor: On the Molecular Basis of Parkinson's Disease
Posted May 19, 2006
Perhaps a million people in the United States endure Parkinson's disease, which becomes increasingly common with age. Among neurodegenerative diseases, only Alzheimer's disease is more prevalent. The symptoms of Parkinson's disease, which include resting tremor, rigidity, slowed movement, and postural instability, can be controlled with drugs, but this approach becomes ineffective over time. Improved treatment of Parkinson's disease will likely require deeper understanding of the molecular events involved. Three leading researchers discussed this approach at a December 8, 2005, symposium of the New York Academy of Sciences' Neurodegenerative Diseases Discussion Group.
General Information and Research
An informational site on Parkinson's disease for patients, primary care physicians, and specialists.
Offers an extensive set of articles offering news and basic information about Parkinson's disease.
National Institute of Neurological Disorders and Stroke
The National Institutes of Health page dedicated to Parkinson's disease offers numerous information sheets and news on developing research and conferences. More information for researchers is available at the Parkinson's Disease Research Web.
American Parkinson Disease Association
This organization offers information for patients and physicians, and funds grants for promising research to find a cure for Parkinson's disease.
The Michael J. Fox Foundation for Parkinson's Research
The largest nonprofit funder of Parkinson's research.
The National Parkinson Foundation (NPF)
Supports Parkinson-related research, patient care, education, training, and outreach.
Parkinson's Disease Foundation
A national non-profit organization devoted to funding research, providing education, and advocating for Parkinson's disease. Information about different types of grants and fellowships for research is also available online.
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Amazon | Barnes & Noble
This popular account describes the discovery of Parkinson's symptoms in users of synthetic heroin contaminated with MPTP.
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A gripping account of the promise and eventual disappointment of L-dopa treatment of victims of post-encephalitic Parkinson's disease.
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Structural Properties and Interactions of the Parkinson's and Alzheimer's Proteins Synuclein and Tau
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Serge Przedborski, MD, PhD
email | web site | publications
Serge Przedborski is the William Black Professor of Neurology and a professor of pathology at Columbia University's College of Physicians and Surgeons in New York. He received his MD degree from the Université Libre de Bruxelles (ULB), Belgium. He did his internship and residency in neurology and psychiatry at the ULB-Erasme Medical Center, Belgium. He received his PhD degree in neurological sciences from ULB School of Medicine, Belgium. His postdoctoral research was done at Columbia University, where he became assistant professor of neurology in 1991.
David Eliezer, PhD
Weill Medical College of Cornell University
email | web site | publications
David Eliezer is associate professor of biochemistry and of the program in structural biology at the Weill Medical College of Cornell University. He received a PhD in physics from Stanford University in 1994, where he studied protein folding kinetics. Before moving to Cornell, he was a postdoctoral fellow at the Scripps Research Institute, where he used high resolution NMR spectroscopy to probe structure in highly and partially unfolded states of proteins.
Benoit Giasson, PhD
University of Pennsylvania
email | web site | publications
Benoit Giasson is an assistant professor of pharmacology at the University of Pennsylvania. He received a PhD in 1997 from McGill University, Montreal, Canada.
Don Monroe is a science writer based in Murray Hill, New Jersey. After getting a PhD in physics from MIT, he spent more than fifteen years doing research in physics and electronics technology at Bell Labs. He writes on biology, physics, and technology.