Posted October 19, 2009
At a May 15, 2006, Science Alliance event, Nobel laureate and immunologist Peter Doherty discussed his career and lessons he learned over the years. Topics included the importance of effective communication and thinking visually, the benefits of collaboration, and the serendipitous nature of scientific discovery. An excerpt from his book, The Beginner's Guide to Winning the Nobel Prize, is also included in this eBriefing.
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Articles by Peter Doherty
Doherty, P. & R. Zinkernagel. 1974. Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature 251 547-548.
Doherty, P. C. & S. J. Turner. 2005. The virus-immunity ecosystem. Arch. Virol. Suppl. 19: 17-32.
Doherty, P. & R. Zinkernagel. 1974. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic chorio-meningitis within a syngeneic or semiallogeneic system. Nature 248: 701-702.
LaGruta, H. L., K. Kedzierska, K. Pang, et al. 2006. A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies. Proc. Natl. Acad. Sci. 103: 994-999. FULL TEXT
Thomas, P. G., S. A. Brown, W. Yue, et al. 2006. An unexpected antibody response to an engineered influenza virus modifies CD8+ T cell responses. Proc. Natl. Acad. Sci. 103: 2764-2769. FULL TEXT
Thomas, P. G., R. Keating, D. J. Hulse-Post, et al. 2006. Cell-mediated protection in influenza infection. Emerg Infect Dis. 12: 48-54.
Peter C. Doherty, PhD
Born in Brisbane, Australia in 1940, Peter Doherty completed bachelor's and master's degrees in veterinary training at the University of Queensland. After receiving his PhD from the University of Edinburgh, he became a postdoctoral fellow at John Curtin School of Medical Research in Canberra. In 1996, Doherty shared the Nobel Prize in Physiology or Medicine with Rolf M. Zinkernagel for discovering how T cells recognize their target antigens in combination with major histocompatibility proteins. Doherty also received the Lasker Prize for Basic Medical Research in 1995. The immunologist divides his time between faculty positions at St. Jude Children's Research Hospital in Memphis, Tennessee, and at the University of Melbourne.