Organizers: Mark Bowlby and John Dunlop, Wyeth Research
Speakers: John Dunlop, Wyeth Research; Terry Snutch, University of British Columbia, Vancouver; Alan Wickenden, J&J PR&D; Mark Bowlby, Wyeth Research; John Wemmie, University of Iowa
Ion channels remain a relatively underexploited target class in terms of drug discovery yet significant advances have been made in understanding the basic biology of many therapeutically relevant channels. This symposium will discuss the latest developments in ion channel drug discovery.
1:00 – 1:10 John Dunlop, Wyeth Research, Princeton, NJ, Introduction: "New Developments in Ion Channel Biology and Drug Discovery."
1:10 – 2:00 Terry Snutch, University of British Columbia, Vancouver, Canada, "Targeting N-type and T-type Calcium Channels for the Treatment of Pain."
2:00 – 2:50 Alan Wickenden, J&J PR&D, San Diego, CA, "TRPV1 and Pain."
2:50 – 3:20 Coffee Break
3:20 – 4:10 Mark Bowlby, Wyeth Research, Princeton, NJ, "Nav Channels as Targets for Chronic Pain."
4:10 – 5:00 John Wemmie, University of Iowa, Iowa City, IA, "Inhibiting ASIC1a Reduces Anxiety-related Behavior."