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Genome Integrity Discussion Group October 2008

Genome Integrity Discussion Group October 2008

Monday, October 20, 2008

The New York Academy of Sciences

Presented By

 

 

Organizers: Titia de Lange, The Rockefeller University; John Petrini, Memorial Sloan-Kettering Cancer Center; Rodney Rothstein, Columbia University Medical Center

The greater New York metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and cell cycle regulation. The Genome Integrity Discussion Group meets four to five times each year and provides an opportunity for researchers active in this area to exchange ideas and form research collaborations.

 

Program

2:00-2:10
Welcome
John Petrini, Memorial Sloan-Kettering Cancer Center

2:10-2:40
Mechanism of Homologous Recombination from the Structure of the RecA-DNA Filament
Nikola Pavletich, Memorial Sloan-Kettering Cancer Center

2:40-3:10
The DNA Replication Fork Under Stress: Does Phosphorylated RPA Deliver the Relief?
James Borowiec, New York University

3:10-3:40
DNA Damage Signaling and DNA Repair
Junjie Chen, Yale University

3:40-4:00
Mouse Spo11β Supports Meiotic Double-Strand Break Formation but not Efficient Chromosome Synapsis
Liisa Kauppi, Memorial Sloan-Kettering Cancer Center (PI: Scottt Keeney)

4:00-4:30
Break

4:30-5:00
Novel Role for a Homeodomain Tumor Suppressor Protein in DNA Repair
Edward Gelmann, Columbia University

5:00-5:30
Antibody Genes and Cancer
Michel Nussenzweig, The Rockefeller University

5:30-5:50
Checkpoint Signaling From a Single DNA Interstrand Crosslink
Lily C. Wang, Columbia University (PI: Jean Gautier)