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Angiogenesis: Breakthroughs in Basic Science and Therapeutic Applications, The 2011 Dr. Paul Janssen Award Symposium
Wednesday, September 14, 2011
In 1989 Napoleone Ferrara, MD, made a breakthrough in the field of angiogenesis, the process of new blood vessel formation that plays a key role in cancer proliferation and a number of other diseases. Ferrara’s discovery of the core angiogenic signaling molecule—vascular endothelial growth factor (VEGF)—opened the door to the development of a new class of therapeutics to combat wet age-related macular degeneration and cancer. In recognition of his achievements, Ferrara will receive the 2011 Dr. Paul Janssen Award for Biomedical Research.
This symposium will honor Ferrara, who will reflect upon the discovery of VEGF and his ongoing research to harness VEGF for the treatment of various diseases with high unmet medical needs. Following Ferrara's award lecture, leading international scientists will speak about what has been learned with respect to the molecular mechanisms and clinical applications of angiogenesis since the original discovery of VEGF, the current challenge of refractoriness to VEGF blockade in advanced cancer, and future directions including therapeutic angiogenesis and the development of biomarkers for personalized anti-angiogenic medicine.
Symposium registration is free. Advance registration is required.
Agenda
* Presentation times are subject to change.
Wednesday, September 14, 2011 | |
| 8:00 AM | Registration and Breakfast |
| 9:00 AM | Welcome and Introductory Remarks Ellis Rubinstein, The New York Academy of Sciences |
| 9:15 AM | 2011 Dr. Paul Janssen Award Announcement Paul Stoffels, MD, Johnson & Johnson Pharmaceutical Research and Development |
| 9:30 AM | 2011 Dr. Paul Janssen Award Presentation |
| Discovery of Anti-Angiogenesis Therapies for Cancer and Ocular Disease Napoleone Ferrara, MD, Genentech, Inc. | |
| 10:15 AM | Ocular Angiogenesis and Therapeutic Approaches to Treating Ocular Neovascular Diseases such as Macular Degeneration Martin Friedlander, MD, PhD, The Scripps Research Institute |
| 10:45 AM | Networking Break |
| 11:30 AM | Current Challenges: Emerging Modes of Resistance to Anti-Angiogenic Therapies Luisa Iruela-Arispe, PhD, UCLA |
| 12:00 PM | Future Directions: Predictive Biomarkers of Response and Resistance to Anti-Angiogenic Therapy Dan G. Duda, PhD, DMD, Massachusetts General Hospital; Harvard Medical School |
| 12:30 PM | Luncheon |
| 2:00 PM | Panel Discussion: Reflections and the Future of Angiogenic Medicine |
| Panelists: Anthony P. Adamis, MD, Genentech, Inc. Dan G. Duda, PhD, DMD, Massachusetts General Hospital; Harvard Medical School Luisa Iruela-Arispe, PhD, UCLA Napoleone Ferrara, MD, Genentech, Inc. Martin Friedlander, MD, PhD, The Scripps Research Institute Moderator: Robert S. Kerbel, PhD, University of Toronto | |
| 3:30 PM | Adjourn |
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This symposium is made possible with support from
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