Cognitive Dysfunction in Multiple Sclerosis
Tuesday, June 21, 2011
In less than two decades remarkable advances have been made in the therapeutics of MS, particularly in the development of disease-modifying treatments for relapsing forms of the disease. From no treatment available prior to 1993, the therapeutic armamentarium has expanded to include 8 FDA-approved agents currently marketed in the US. Many other drugs and biologicals are in advanced stages of clinical development, with several having reported successful results in Phase III trials. These have novel mechanisms of action and more desirable routes or frequency of administration than the injectable drugs that have been the mainstay of MS therapy in the 1990s and the first decade of the 21st century. These advances will make the treatment of MS more effective, but also more challenging and complex as MS specialists seek to optimize treatment on an individual basis. While therapeutic activity for relapsing MS has perhaps exceeded that in all of neurology during the past two decades, nonetheless the lack of effective therapy for progressive forms of MS remains a major disappointment. This talk will highlight the currently marketed drugs, describe the new therapeutic agents nearing possible FDA approval, and review the issues that continue to confront investigators in the field.
Reception to follow.
Aaron E. Miller, MD
Mount Sinai School of Medicine
Jeffery N. Gingold
MS Patient Advocate
Nicholas G. LaRocca, PhD
National Multiple Sclerosis Society
MS Patient Advocate
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*Presentation times are subject to change.
American Neurological Association
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