
FREE
for Members
Genome Integrity Discussion Group April 2011
Monday, April 4, 2011
The New York Academy of Sciences
The greater New York Metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity meetings are designed to provide a forum for interactions between the many basic science and clinically-oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities will be revealed.
In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.
The Genome Integrity Meetings are organized under the leadership of John Petrini (Memorial Sloan Kettering Cancer Center), and Rodney Rothstein and Lorraine Symington (Columbia University). The April 2011 meeting includes a scientific symposium from 2:00 to 5:15 PM, followed by a networking reception from 5:15 to 6:00 PM.
Networking reception to follow.
Agenda
*Presentation times are subject to change.
2:00 PM | Understanding the Complexity of the Human RECQ Helicases in Genome Maintenance |
2:30 PM | XLF Has Overlapping Functions with ATM and Its Substrates during V(D)J Recombination and DNA Repair |
3:00 PM | The Pif1 Helicase, More Than an Inhibitor of Telomerase, Promotes Genome Stability at G4 Motifs |
3:30 PM | ATM Modulates RAG-mediated Monoallelic Looping of the 3’ End of the Tcra Locus to Control Accessibility and Cleavage |
3:45 PM | Coffee Break |
4:00 PM | Function and Formation of a Nucleosome-depleted Region |
4:15 PM | Genetic Analysis of the DNA Damage Response |
4:45 PM | Aberrant Base Excision Repair and Cancer |
5:15 PM | Networking Reception |
Speakers
Organizers
John Petrini, PhD
Memorial Sloan-Kettering Cancer Center
Rodney Rothstein, PhD
Columbia University Medical Center
Lorraine Symington, PhD
Columbia University Medical Center
Speakers
Yilun Liu, PhD
Yale University
John Petrini, PhD
Memorial Sloan-Kettering Cancer Center
Joann Sweasy, PhD
Yale University
Ginger Zakian, PhD
Princeton University
Shan Zha, MD, PhD
Columbia University Medical Center
Sponsors
For sponsorship opportunities please contact Carmen McCaffery at cmccaffery@nyas.org or 212.298.8642.
Presented by
Academy Friend
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Our Location
The New York Academy of Sciences
7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600
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