Genome Integrity Discussion Group Meeting (3)

FREE

for Members

Genome Integrity Discussion Group Meeting

Monday, February 7, 2011

The New York Academy of Sciences

Presented By

 

The greater New York Metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity meetings are designed to provide a forum for interactions between the many basic science and clinically-oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities will be revealed.

In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.

The Genome Integrity Meetings are organized under the leadership of John Petrini (Memorial Sloan Kettering Cancer Center), and Rodney Rothstein and Lorraine Symington (Columbia University). Meetings include a scientific symposium from 2:00 to 5:30 PM, followed by a networking reception from 5:30 to 6:30 PM.

Organizers

John Petrini, PhD

Memorial Sloan-Kettering Cancer Center

Rodney Rothstein, PhD

Columbia University Medical Center

Lorraine Symington, PhD

Columbia University Medical Center

Speakers

Eric Greene, PhD

Columbia University Medical Center

Prasad Jallepalli, MD, PhD

Memorial Sloan-Kettering Cancer Center

Susan Smith, PhD

New York University

Agata Smogorzewska, MD, PhD

The Rockefeller University

Iestyn Whitehouse, PhD

Memorial Sloan-Kettering Cancer Center

Networking reception to follow.

Agenda

*Presentation times are subject to change.


1:30 PM

Registration

2:00 PM

HP1 Binding to the Dyskeratosis Congenita Mutation Cluster in TIN2 is Required for Telomere Maintenance
Susan Smith, PhD, New York University

2:30 PM

Visualizing Protein-DNA Interactions at the Single Molecule Level
Eric Greene, PhD, Columbia University Medical Center

3:00 PM

Chromatin and the Lagging Strand
Iestyn Whitehouse, PhD, Memorial Sloan-Kettering Cancer Center

3:30 PM

Dissection of Homologous Recombination Outcomes at a Mouse Hotspot Delineates DNA Double-strand Break Repair Pathways
Francesca Cole (Jasin lab, Memorial Sloan-Kettering Cancer Center)

3:45 PM

Coffee Break

4:15 PM

Switching Cdk2 On and Off with Small Molecules to Reveal Essential Functions in Human Cell Division
Karl Merrick (Fisher lab, Mount Sinai School of Medicine)

4:30 PM

New Players in Fanconi Anemia
Agata Smogorzewska, MD, PhD, The Rockefeller University

5:00 PM

Making and Breaking the "wait anaphase" Signal
Prasad Jallepalli, MD, PhD, Memorial Sloan-Kettering Cancer Center

5:30 PM

Networking Reception

Sponsors

For sponsorship opportunities please contact Cristine Barreto at cbarreto@nyas.org or 212.298.8652.

Presented by

Academy Friend

Travel & Lodging

Our Location

The New York Academy of Sciences

7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600

Click here for directions.

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