
FREE
for Members
Genome Integrity Discussion Group February 2011
Monday, February 7, 2011
The New York Academy of Sciences
The greater New York Metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity meetings are designed to provide a forum for interactions between the many basic science and clinically-oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities will be revealed.
In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.
The Genome Integrity Meetings are organized under the leadership of John Petrini (Memorial Sloan Kettering Cancer Center), and Rodney Rothstein and Lorraine Symington (Columbia University). Meetings include a scientific symposium from 2:00 to 5:30 PM, followed by a networking reception from 5:30 to 6:30 PM.
Organizers
John Petrini, PhD
Memorial Sloan-Kettering Cancer Center
Rodney Rothstein, PhD
Columbia University Medical Center
Lorraine Symington, PhD
Columbia University Medical Center
Speakers
Eric Greene, PhD
Columbia University Medical Center
Prasad Jallepalli, MD, PhD
Memorial Sloan-Kettering Cancer Center
Susan Smith, PhD
New York University
Agata Smogorzewska, MD, PhD
The Rockefeller University
Iestyn Whitehouse, PhD
Memorial Sloan-Kettering Cancer Center
Networking reception to follow.
Agenda
*Presentation times are subject to change.
1:30 PM | Registration |
2:00 PM | HP1 Binding to the Dyskeratosis Congenita Mutation Cluster in TIN2 is Required for Telomere Maintenance |
2:30 PM | Visualizing Protein-DNA Interactions at the Single Molecule Level |
3:00 PM | Chromatin and the Lagging Strand |
3:30 PM | Dissection of Homologous Recombination Outcomes at a Mouse Hotspot Delineates DNA Double-strand Break Repair Pathways |
3:45 PM | Coffee Break |
4:15 PM | Switching Cdk2 On and Off with Small Molecules to Reveal Essential Functions in Human Cell Division |
4:30 PM | New Players in Fanconi Anemia |
5:00 PM | Making and Breaking the "wait anaphase" Signal |
5:30 PM | Networking Reception |
Sponsors
For sponsorship opportunities please contact Cristine Barreto at cbarreto@nyas.org or 212.298.8652.
Presented by
Academy Friend
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Our Location
The New York Academy of Sciences
7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600
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