Genome Integrity Discussion Group Meeting


for Members

Genome Integrity Discussion Group Meeting

Monday, October 3, 2011

The New York Academy of Sciences

Presented By


The greater New York metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity Discussion Group meetings are designed to provide a forum for interactions between the many basic science and clinically oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs but also provide a context in which previously unappreciated complementarities will be revealed.

In that spirit, the talks will cover a broad range of areas, including, but not limited to, the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although the primary focus is on basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.

The Genome Integrity meetings are organized under the leadership of John Petrini (Memorial Sloan-Kettering Cancer Center) and Rodney Rothstein and Lorraine Symington (Columbia University Medical Center).

This meeting includes a scientific symposium from 2:00 to 5:30 PM, followed by a networking reception from 5:30 to 6:30 PM.

Registration Pricing

Student / Postdoc / Fellow Member:$0
Student / Postdoc / Fellow Nonmember:$15


*Presentation times are subject to change.

1:30 PM


2:00 PM

Genetic and Epigenetic Instability in Mammalian Stem Cells
Tim Bestor, PhD, Columbia University

2:30 PM

RNA Polymerse Backtracking in Gene Regulation and Genome Instability
Evgeny Nudler, PhD, New York University

3:00 PM

Regulation of ATM Homolog Tell at DNA Ends
Katsunori Sugimoto, PhD, UMDNJ Newark

3:30 PM

ATM Controls Meiotic Double-Strand Break Formation
Julian Lange, PhD (Keeney Lab, Memorial Sloan-Kettering Cancer Center)

3:45 PM

Coffee Break

4:15 PM

The Outcome of Complete Shelterin Loss
Agnel Sfeir, PhD (de Lange Lab, The Rockefeller University)

4:30 PM

Mechanistic Analysis of the 5’-> 3’ Processing of DNA Double-Strand Breaks for Homology-Dependent Repair
Hong Yan, PhD, Fox Chase Cancer Center

5:00 PM

Sumoylation and Genome Maintenance
Xiaolan Zhao, PhD, Memorial Sloan-Kettering Cancer Center

5:30 PM

Networking Reception



John Petrini, PhD

Memorial Sloan-Kettering Cancer Center

Rodney Rothstein, PhD

Columbia University Medical Center

Lorraine Symington, PhD

Columbia University Medical Center


Tim Bestor, PhD

Columbia University

Julian Lange, PhD

Memorial Sloan-Kettering Cancer Center

Evgeny Nudler, PhD

New York University

Agnel Sfeir, PhD

The Rockefeller University

Katsunori Sugimoto, PhD

UMDNJ Newark

Hong Yan, PhD

Fox Chase Cancer Center

Xiaolan Zhao, PhD

Memorial Sloan-Kettering Cancer Center


Travel & Lodging

Our Location

The New York Academy of Sciences

7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157

Directions to the Academy

Hotels Near 7 World Trade Center

Recommended partner hotel

Club Quarters, World Trade Center
140 Washington Street
New York, NY 10006
Phone: 212.577.1133

The New York Academy of Sciences is a member of the Club Quarters network, which offers significant savings on hotel reservations to member organizations. Located opposite Memorial Plaza on the south side of the World Trade Center, Club Quarters, World Trade Center is just a short walk to the Academy.

Use Club Quarters Reservation Password NYAS to reserve your discounted accommodations online.

Other nearby hotels

Millenium Hilton


Marriott Financial Center


Club Quarters, Wall Street


Eurostars Wall Street Hotel


Gild Hall, Financial District


Wall Street Inn


Ritz-Carlton New York, Battery Park