Genome Integrity Discussion Group Meeting (1)

Genome Integrity Discussion Group Meeting

Monday, October 6, 2014

The New York Academy of Sciences

Presented By

Presented by the Genome Integrity Discussion Group at the New York Academy of Sciences.

 

The greater New York Metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity meetings are designed to provide a forum for interactions between the many basic science and clinically-oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities will be revealed.

In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.

Genome Integrity Discussion Group meetings are organized under the leadership of Scott Keeney (Memorial Sloan Kettering Cancer Center), Susan Smith (NYU Langone Medical Center) and Lorraine Symington (Columbia University). This meeting will include a scientific symposium from 1:30 to 4:30 PM, followed by a networking reception from 4:30 to 5:30 PM.

Registration Pricing

Member$0
Member (Student / Postdoc / Resident / Fellow)$0
Nonmember$40
Nonmember (Student / Postdoc / Resident / Fellow)$20


The Genome Integrity Discussion Group is proudly supported by

  • Memorial Sloan Kettering Cancer Center
  • NYU Langone Medical Center
  • Rockefeller University


Mission Partner support for the Frontiers of Science program provided by   Pfizer

Agenda

* Presentation titles and times are subject to change.

October 6, 2014

1:30 PM

Welcome and Introductory Remarks

1:40 PM

Organization and Dynamics of the NHEJ Complex in DNA Double-strand Break Repair
Eli Rothenberg, PhD, NYU

2:10 PM

Mammalian Polymerase Theta Promotes Alternative-NHEJ and Suppresses Recombination
Agnel Sfeir, PhD, Skirball Institute of Biomolecular Medicine, New York University School of Medicine

2:40 PM

Short Talk
The Repression of PARP1 Activation at Telomeres
Isabelle Schmutz, PhD, The Rockefeller University

2:55 PM

Networking Coffee Break

3:25 PM

Short Talk
The Synaptonemal Complex – A Checkpoint Signal that Dictates Template Choice for Meiotic Recombination
Viji Subramanian, PhD, New York University

3:40 PM

Conserved RAG2 Phosphorylation Site Controls V(D)J Recombination to Promote Genome Stability
Jane A. Skok, PhD, New York University Langone Medical Center

4:10 PM

Sae2 Promotes DNA Damage Resistance by Removing the Mre11-Xrs2-Rad50 Complex from DNA and Attenuating Rad53 Signaling
Lorraine Symington, PhD, Columbia University Medical Center

4:40 PM

Networking Reception

5:30 PM

Close

Speakers

Organizers

Scott Keeney, PhD

Memorial Sloan-Kettering Cancer Center

Susan Smith, PhD

NYU Langone Medical Center

Lorraine Symington, PhD
Columbia University Medical Center

Speakers

Eli Rothenberg, PhD

New York University School of Medicine

Agnel Sfeir, PhD

Skirball Institute of Biomolecular Medicine, New York University School of Medicine

Isabelle Schmutz, PhD

The Rockefeller University

Viji Subramanian, PhD

New York University

Jane A. Skok, PhD

New York University Langone Medical Center

Lorraine S. Symington, PhD

Columbia University Medical Center

Sponsors

For sponsorship opportunities please contact Perri Wisotsky at pwisotsky@nyas.org or 212.298.8642.

Academy Friend

Abcam

Promotional Partner

Nature

The Genome Integrity Discussion Group is proudly supported by

  • Memorial Sloan Kettering Cancer Center
  • NYU Langone Medical Center
  • Rockefeller University

Travel & Lodging

Our Location

The New York Academy of Sciences

7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600

Directions to the Academy

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