Genome Integrity Discussion Group February 2014
Monday, February 3, 2014
The New York Academy of Sciences
Presented by the Genome Integrity Discussion Group
The greater New York Metropolitan area has become a leading center for research on chromosome biology and function, as well as for research at the interface between chromosome integrity and onset and progression of malignancy. The connection between cancer and genome integrity is widely appreciated, and the concentration of excellence in this field is unparalleled anywhere in the world. The Genome Integrity meetings are designed to provide a forum for interactions between the many basic science and clinically-oriented research groups working on these issues. We feel that these interactions will not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities will be revealed.
In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions.
Genome Integrity Discussion Group meetings are organized under the leadership of John Petrini (Memorial Sloan Kettering Cancer Center), Susan Smith (NYU Langone Medical Center) and Lorraine Symington (Columbia University). This meeting will include a scientific symposium from 1:30 to 4:30 PM, followed by a networking reception from 4:30 to 5:30 PM.
*Reception to follow.
|Nonmember (Student / Postdoc / Resident / Fellow)||$20|
The Genome Integrity Discussion Group is proudly supported by
Mission Partner support for the Frontiers of Science program provided by
* Presentation titles and times are subject to change.
February 3, 2014
Non-coding RNA Processing-Mediated Regulation of Somatic Mutations in the B Cell Genome
Causes of Replication Fork Collapse Following ATR-CHK1 Inhibition
Nuclear Pores Protect Genome Integrity by Assembling a Premitotic and MAD1-Dependent Anaphase
Chromosome Segregation Requires Kinetochore and Central Spindle Components in Drosophila Oocytes
Friends and Foes of53BP1 In Mammalian Double-Strand Break Resection
How CDKs Uphold Transcriptome Integrity: Insights from Chemical Genetics
John Petrini, PhD
Memorial Sloan-Kettering Cancer Center
Susan Smith, PhD
NYU Langone Medical Center
Lorraine Symington, PhD
Columbia University Medical Center
Uttiya Basu, PhD
Eric J. Brown, PhD
University of Pennsylvania
Samuel F. Bunting, PhD
Robert P. Fisher, MD, PhD
Icahn School of Medicine at Mount Sinai
Sarah J. Radford, PhD
McKim Lab, Waksman Institute, Rutgers University
Veronica Rodriguez-Bravo, PhD
Jallepalli Lab, Memorial Sloan-Kettering Cancer Center
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