Disease Drivers of Aging: 2016 Advances in Geroscience Summit
Wednesday, April 13, 2016 - Thursday, April 14, 2016
The New York Academy of Sciences
Presented By
The Gerontological Society of America
American Federation for Aging Research
The Trans-NIH GeroScience Interest Group
The New York Academy of Sciences
Cellular and organismal decline with aging has been shown to promote chronic disease pathology, however insufficient research has focused on the inverse relationship, i.e., how chronic diseases and associated therapies can accelerate the onset of age-related changes. In October 2013, the National Institutes of Health hosted the groundbreaking event, Advances in Geroscience: Impact on Healthspan and Chronic Disease, a highly successful convening developed by the Trans-NIH GeroScience Interest Group (GSIG). This event was designed to explore how aging contributes to chronic disease pathology and progression, but it also highlighted the pressing need for further research on the impact of chronic diseases on the molecular pillars of aging.
To address this unmet need and to gather the community for a follow-up meeting, the New York Academy of Sciences, together with the NIH Geroscience Interest Group, the Gerontological Society of America and the American Federation for Aging Research will present the 1.5-day Disease Drivers of Aging: 2016 Advances in Geroscience Summit on April 13–14, 2016, in New York City. This landmark event will convene basic, translational, and clinical researchers from academic institutions, pharmaceutical companies, government agencies, and non-profit organizations, who work in the disparate fields of HIV/AIDS, oncology, diabetes, and aging research in an effort to better understand the complex relationship between chronic diseases and age-associated decline. Conference Sessions will combine basic, translational, and clinical researchers and will feature a unique format of short, focused talks centered on critical open research questions, along with interactive panel discussions. Speakers will explore the impact of chronic diseases (e.g., HIV/AIDS, diabetes, and cancer) and their associated therapies on rates of cellular and organismal aging in an attempt to elucidate the molecular mechanisms by which chronic diseases and treatments can accelerate age-related health decline. Participants will identify knowledge gaps and future directions of research required for a more complete understanding of the relationship between chronic diseases and aging.
Registration Pricing
| By 03/01/2016 | After 03/01/2016 | Onsite | |
| Member | $100 | $150 | $200 |
| Member (Student / Postdoc / Resident / Fellow) | $75 | $100 | $150 |
| Nonmember (Academia) | $175 | $225 | $300 |
| Nonmember (Corporate) | $225 | $275 | $350 |
| Nonmember (Non-profit) | $175 | $225 | $300 |
| Nonmember (Student / Postdoc / Fellow) | $100 | $125 | $175 |
Agenda
* Presentation titles and times are subject to change.
Day 1: Wednesday, April 13, 2016 | |||||||
8:00 AM | Breakfast, Registration, and Poster Set-Up | ||||||
8:30 AM | Opening Remarks | ||||||
Session I. Keynote PresentationsChairperson: Ronald Kohanski, PhD, National Institutes on Aging (NIA) and Geroscience Interest Group; National Institutes of Health (NIH) | |||||||
8:50 AM | Geroscience as a Multidisciplinary Approach to Understanding Aging | ||||||
9:20 AM | Disease Drivers of Aging as a Topic of Geroscience | ||||||
9:35 AM | The Geroscience Hypothesis: What Do We Know? | ||||||
10:05 AM | Physiological Stress, Chronic Diseases, and Telomere Length | ||||||
10:35 AM | Coffee Break | ||||||
Session II. Aging with HIV: Responding to an Emerging Challenge | |||||||
11:05 AM | Introduction | ||||||
11:15 AM | Acceleration of Immune Senescence by a Chronic Viral Infection (HIV and CMV) | ||||||
11:25 AM | How is Cognitive Function Affected by Chronic HIV Infection? | ||||||
11:35 AM | The Bidirectional Relationship between Stress and HIV | ||||||
11:45 AM | How are Women’s Health Issues and/or Hormonal Influences Affected by HIV? | ||||||
11:55 AM | Gut Barrier, Microbiome, and Health in HIV and Aging | ||||||
12:05 PM | From Wasting to Obesity: HIV and its Therapy in Aging | ||||||
12:15 PM | Moderated Panel Discussion | ||||||
12:50 PM | Networking Lunch Early Career Investigator and Underrepresented Minority Mentoring Lunch | ||||||
Session III. Emerging Science: Hot Topic TalksChairperson: Ronald Kohanski, PhD, National Institutes on Aging (NIA) and Geroscience Interest Group; National Institutes of Health (NIH) | |||||||
1:45 PM | Comorbidity Trajectories among Cancer Survivors: A Potential Example of Premature Aging | ||||||
2:05 PM | GDF11 is a Biomarker of Frailty, Comorbidity, and Adverse Surgical Health Outcomes in Older Adults with Cardiovascular Disease | ||||||
2:25 PM | Mitochondrial Dysfunction-associated Senescence as a Promoter of Lipoatrophy in Response to Antiretroviral Therapy | ||||||
2:45 PM | DNA Methylation Age Is Accelerated Prior to AIDS-NHL Diagnosis | ||||||
3:05 PM | Coffee Break | ||||||
Session IV. Examining the Impacts of Diabetes on Aging | |||||||
3:45 PM | Introduction | ||||||
3:55 PM | How Does Diabetes and Aberrant Insulin Signaling Accelerate the Effects of Aging in the Brain and Neurovascular System? | ||||||
4:05 PM | The Calpain System in Aging | ||||||
4:15 PM | How Does Diabetes Affect the Seven Pillars of Aging in the Kidneys? | ||||||
4:25 PM | How Does Diabetes Affect Functional Mobility? | ||||||
4:35 PM | Does Diabetes Accelerate Aging of Beta Cells through Hyperglycemia (Glucose Toxicity) and Also Insulin Resistance? | ||||||
4:45 PM | Moderated Panel Discussion | ||||||
5:30 PM | Poster Session and Networking Reception | ||||||
6:45 PM | Conclusion of Day 1 | ||||||
Day 2: Thursday, April 14, 2016 | |||||||
8:00 AM | Breakfast | ||||||
8:15 AM | Early Career Investigator Mentoring Workshop (concurrent) Editor's Guide to Writing and Publishing Your Paper | ||||||
Session V. Understanding and Mitigating Premature Aging Due To Cancer and Chemotherapy | |||||||
9:00 AM | Introduction | ||||||
9:10 AM | How Senescent Cells Contribute to Aging and Disease | ||||||
9:20 AM | How Does Activation of Inflammatory and Coagulation Pathways in Cancer Patients Affect Survivorship and Functional Status? | ||||||
9:30 AM | Which Animal and/or Cellular Models are Best for Studying the Effects of Cancer and Cancer Therapy on the Aging Process? | ||||||
9:40 AM | Functional Decline In the Older Cancer Patient...Can Lifestyle Interventions Turn Back the Hands of Time? | ||||||
9:50 AM | How Does Cancer and/or Cancer Treatment Impact Cognitive Aging? | ||||||
10:00 PM | Moderated Panel Discussion | ||||||
10:45 AM | Coffee Break | ||||||
Session VI. Identifying Common Themes and Open Research Questions to Advance Therapies for Chronic Diseases and Aging
| |||||||
11:15 AM | What are the Common Themes/Threads That Have Emerged in the Areas of HIV/AIDS, Diabetes, and Cancer as They Pertain to the Biology of Aging? | ||||||
11:45 AM | What Are the Open Research Questions That Need to Be Addressed to Advance Our Understanding of How HIV/AIDS, Diabetes, and Cancer Impact the Aging Process? | ||||||
12:15 PM | If Chronic Diseases Are Accelerating Aging, How Will That Impact Disease Follow-Up and/or Aging Treatments? | ||||||
12:45 PM | Networking Lunch | ||||||
1:45 PM | Conference Concludes | ||||||
Organizers
Siobhan Addie, PhD
The New York Academy of Sciences
James Appleby, RPh, MPH
The Gerontological Society of America
website
Steven Austad, PhD
University of Alabama at Birmingham
Rita Effros, PhD
University of California, Los Angeles
website
Rebecca Fuldner, PhD
National Institute on Aging; National Institutes of Health
Paige Green, PhD, MPH
National Cancer Institute; National Institutes of Health
website
Brooke Grindlinger, PhD
The New York Academy of Sciences
Robin Huebner, PhD, MPH
National Institute of Allergy and Infectious Diseases; National Institutes of Health
Ronald Kohanski, PhD
National Institute on Aging; National Institutes of Health
Stephanie Lederman, EdM
American Federation for Aging Research
website
Kevin J. Lee, PhD
The Lawrence Ellison Foundation; American Federation for Aging Research
Judie Lieu
The Gerontological Society of America
Francesca Macchiarini, PhD
National Institute of Allergy and Infectious Diseases; National Institutes of Health
Susan McCarthy, PhD
National Cancer Institute; National Institutes of Health
website
Aaron Pawlyk, PhD
National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health
website
Felipe Sierra, PhD
National Institute on Aging; National Institutes of Health
website
Luke Stoeckel, PhD
National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health
website
Odette van der Willik
American Federation for Aging Research
website
Speakers
Timothy Ahles, MD
Memorial Sloan Kettering Cancer Center
Kathryn Anastos, MD
Albert Einstein College of Medicine
website
Nir Barzilai, MD
Albert Einstein College of Medicine
James Becker, PhD
University of Pittsburgh
Caroline Blaum, MD
New York University
website
Judith Campisi, PhD
Buck Institute for Research on Aging
website
Harvey J. Cohen, MD
Duke University
website
Steven Deeks, MD
AIDS Research Institute; University of California, San Francisco
Wendy Demark-Wahnefried, MD
University of Alabama at Birmingham
website
Elissa Epel, MD
University of California, San Francisco
website
Kristine Erlandson, MD
University of Colorado
Claudia Gravekamp, PhD
Albert Einstein College of Medicine
Jeffrey Halter, MD
University of Michigan
Kevin High, MD
Wake Forest University
website
Richard Hodes, MD
National Institute on Aging (NIA); National Institutes of Health (NIH)
Peter Hunt, MD
University of California, San Francisco
website
Arti Hurria, MD
City of Hope National Medical Center
website
Beth Jamieson, PhD
University of California, Los Angeles
C. Ronald Kahn, PhD
Joslin Diabetes Center
Balakuntalam Kasinath, MD
Barshop Institute for Longevity and Aging Studies; University of Texas Health Science Center
Gretchen Neigh, PhD
Virginia Commonwealth University
Rosario Scalia, MD, PhD
Temple University
website
Jan van Deursen, PhD
Mayo Clinic
website
Sponsors
For sponsorship opportunities please contact Melanie Brickman Stynes, PhD, at mbrickman@nyas.org or 212.298.8655.
Silver Sponsor
Academy Friends
American Federation for Aging Research
The Gerontological Society of America
Grant Support
Funding for this conference was made possible, in part, by 1 R13 AG 053043-01 from the National Institute on Aging. Co-funding has been provided by the National Institute of Diabetes and Digestive and Kidney Diseases, and the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
This activity is supported by an educational grant from Lilly. For further information concerning Lilly grant funding visit www.lillygrantoffice.com
Regeneron Pharmaceuticals, Inc.
Promotional Partners
Buck Institute for Research on Aging
Cancer and Aging Research Group
Columbia Diabetes Research Center
Mechanisms of Ageing and Development
NPJ Aging and Mechanisms of Disease
Presented by
Travel & Lodging
Special Needs and Additional Information
For any additional information and for special needs, including child/family care resources available to conference attendees, please e-mail jcurtin@nyas.org or call 212.298.8694.
Our Location
The New York Academy of Sciences
7 World Trade Center
250 Greenwich Street, 40th floor
New York, NY 10007-2157
212.298.8600
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