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Chemical Biology Discussion Group Year-End Symposium


for Members

Chemical Biology Discussion Group Year-End Symposium

Wednesday, May 24, 2017

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York, USA

Chemical biology is a dynamic field that explores chemical approaches to studying and manipulating biological systems. The goal of the Academy's Chemical Biology Discussion Group is to enhance interactions among local-area laboratories working in chemical biology and to feature forefront research in chemical biology to the wider community. The meeting traditionally covers a range of topics in chemical biology, including chemical probe development, organic synthesis, biosynthesis, protein engineering, nanotechnology, and drug discovery. The annual year-end meeting features distinguished keynote speakers Professor Dirk Trauner, NYU and Associate Professor Sean F. Brady, The Rockefeller University. There will also be shorter, cutting-edge talks, and a poster session.

Call for Abstracts

Abstract submissions are invited for a poster session, and five abstracts will be selected for short talk presentations. For complete submission instructions, please send an email to with the words "Abstract Information" in the subject line. The deadline for abstract submission is March 24, 2017.

Registration Pricing

Member (Student / Postdoc / Resident / Fellow)$0
Nonmember (Academia)$65
Nonmember (Corporate)$75
Nonmember (Non-profit)$65
Nonmember (Student / Postdoc / Resident / Fellow)$30


Nonmember Academia, Faculty, etc.
Nonmember Corporate, Other
Nonmember Not for Profit
Nonmember Student, Undergrad, Grad, Fellow
Member Student, Post-Doc, Fellow


The Chemical Biology Discussion is proudly supported by

ACS New York Section

The Rockefeller University

Premiere Supporter

Academy Friends

Thermo Fisher Scientific

Tri-Institutional Therapeutics Discovery Institute


* Presentation titles and times are subject to change.

May 24, 2017

11:30 AM

Registration and Poster Set-Up

12:00 PM

Welcome and Introduction
Caitlin McOmish PhD, The New York Academy of Sciences
Howard Hang, PhD, The Rockefeller University

12:15 PM

Keynote Presentation
Culture Independent Discovery of Bioactive Bacterial Small Molecules
Sean Brady, PhD, The Rockefeller University

1:00 PM

Oxazolidinone Mediated High Throughput Sequencing of Cyclic Peptides
Hader E. Elashal, MsC, Seton Hall University

1:15 PM

Discovery and Investigation of Antitrypanosomal Alkaloids for Chagas Disease
Corinne N. Foley, PhD, Memorial Sloan Kettering Cancer Center

1:30 PM

Discovery of a Novel Nitric Oxide Responsive Pathway and a Putative Nitric Oxide Sensor (NosP)
Sajjad Hossain, PhD, Stony Brook University

1:45 PM

Networking Coffee Break

2:15 PM

Using the Hydrogen Bond Surrogate Approach to Stabilize Beta-Hairpins
Nicholas Sawyer, PhD, New York University

2:30 PM

Subtype-Selective Lethal Molecules Disrupt the Regulatory Module That Drives Neuroblastoma
Michael Stokes, PhD, Columbia University

2:45 PM

Keynote Presentation
Controlling Biological Function with Photopharmacology
Dirk Trauner, PhD, New York University

3:30 PM

Poster Session and Networking Reception

4:50 PM

F1000Research Outstanding Poster Presentation Awards
Howard Hang, PhD, The Rockefeller University

5:00 PM



Controlling Biological Function with Photopharmacology
Dirk Trauner, PhD, New York University

Light can be used to control biological events with unmatched temporal and spatial precision, which explains the current excitement about optogenetics. Over the last decade, our group has developed a chemical variant of optogenetics that relies on synthetic photoswitches (photopharmacology). These can be tethered covalently or bind non-covalently to a wide variety of proteins, including ion channels, GPCRs, enzymes, molecular motors, and components of the cytoskeleton, effectively turning them into photoreceptors. I will discuss the advantages and disadvantages of photopharmacology and its potential in biology and medicine, in particular with respect to restoring vision, controlling beta-cell function and fighting cancer.