Chemical Biology Discussion Group Year-End Symposium
Wednesday, May 24, 2017
The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York, USA
Chemical biology is a dynamic field that explores chemical approaches to studying and manipulating biological systems. The goal of the Academy's Chemical Biology Discussion Group is to enhance interactions among local-area laboratories working in chemical biology and to feature forefront research in chemical biology to the wider community. The meeting traditionally covers a range of topics in chemical biology, including chemical probe development, organic synthesis, biosynthesis, protein engineering, nanotechnology, and drug discovery. The annual year-end meeting features distinguished keynote speakers Professor Dirk Trauner, NYU and Associate Professor Sean F. Brady, The Rockefeller University. There will also be shorter, cutting-edge talks, and a poster session.
Call for Abstracts
Abstract submissions are invited for a poster session, and five abstracts will be selected for short talk presentations. For complete submission instructions, please send an email to ChemBio2017@nyas.org with the words "Abstract Information" in the subject line. The deadline for abstract submission is March 24, 2017.
|Member (Student / Postdoc / Resident / Fellow)||$0|
|Nonmember (Student / Postdoc / Resident / Fellow)||$30|
* Presentation titles and times are subject to change.
May 24, 2017
Registration and Poster Set-Up
Welcome and Introduction
Oxazolidinone Mediated High Throughput Sequencing of Cyclic Peptides
Discovery and Investigation of Antitrypanosomal Alkaloids for Chagas Disease
Discovery of a Novel Nitric Oxide Responsive Pathway and a Putative Nitric Oxide Sensor (NosP)
Networking Coffee Break
Using the Hydrogen Bond Surrogate Approach to Stabilize Beta-Hairpins
Subtype-Selective Lethal Molecules Disrupt the Regulatory Module That Drives Neuroblastoma
Poster Session and Networking Reception
F1000Research Outstanding Poster Presentation Awards
Controlling Biological Function with Photopharmacology
Dirk Trauner, PhD, New York University
Light can be used to control biological events with unmatched temporal and spatial precision, which explains the current excitement about optogenetics. Over the last decade, our group has developed a chemical variant of optogenetics that relies on synthetic photoswitches (photopharmacology). These can be tethered covalently or bind non-covalently to a wide variety of proteins, including ion channels, GPCRs, enzymes, molecular motors, and components of the cytoskeleton, effectively turning them into photoreceptors. I will discuss the advantages and disadvantages of photopharmacology and its potential in biology and medicine, in particular with respect to restoring vision, controlling beta-cell function and fighting cancer.